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(newest | oldest) View (newer 50 | older 50) (20 | 50 | 100 | 250 | 500)- 15:51, 14 November 2022 Aidan talk contribs created page Good syndrome (Created page with "* Adult-onset combined B- and T-cell primary immunodeficiency * Associated with thymoma * Associated with a spectrum of autoimmune diseases * Very rare, with less than 200 reported cases == Further Reading == * Good Syndrome: An Adult-Onset Immunodeficiency Remarkable for Its High Incidence of Invasive Infections and Autoimmune Complications. ''Clin Infect Dis''. 2015;61(2):e13-e19. doi: [https://doi.org/10.1093/cid/civ269 10.1093/cid/civ269]") Tag: Visual edit
- 00:05, 14 November 2022 Aidan talk contribs created page Hansen disease (Redirected page to Mycobacterium leprae) Tags: New redirect Visual edit
- 13:32, 13 November 2022 Aidan talk contribs created page PEN-FAST (Created page with "== Background == * Clinical decision rule to help with delabelling penicillin allergy * Used to predict the results of penicillin allergy testing (skin prick testing, intradermal testing, patch testing, or oral challenge) == Criteria == {| class="wikitable" !Criterion !Details !Points |- |'''F'''ive or fewer years ago | |2 |- |'''A'''naphylaxis or angioedema, or '''S'''evere adverse cutaneous reaction (SCAR) |includes AGEP, DRESS, SJS, and TEN |2 |-...") Tag: Visual edit
- 11:42, 11 November 2022 Aidan talk contribs moved page Kaposi sarcoma–associated herpesvirus to Kaposi sarcoma-associated herpesvirus without leaving a redirect
- 11:42, 11 November 2022 Aidan talk contribs created page KSHV (Redirected page to Kaposi sarcoma–associated herpesvirus) Tags: New redirect Visual edit
- 14:30, 10 November 2022 Aidan talk contribs created page CDI (Redirected page to Clostridioides difficile) Tags: New redirect Visual edit
- 12:01, 9 November 2022 Aidan talk contribs created page Cefipime (Created page with "== Background == * Cephalosporin antibiotic == Safety == === Adverse Drug Effects === * Neurotoxicity, which can include altered mental status, myoclonus, and non-convulsive status epilepticus<ref>Gozun Maan, Koichi Keitoku, Nobuhiko Kimura, Haruki Sawada, Andrew Pham, Jihun Yeo, Hideharu Hagiya, Yoshito Nishimura, Cefepime-induced neurotoxicity: systematic review, ''Journal of Antimicrobial Chemotherapy'', Volume 77, Issue 11, November 2022, Pages 2908–2921, http...") Tag: Visual edit
- 22:50, 6 November 2022 Aidan talk contribs created page Transient ischemic attack and minor stroke (Created page with "== Clinical Manifestations == * Presentations are myriad * Most classic is sudden loss of motor function and impaired speech * Not typically progressive, repetitive, or stereotyped * Symptoms are negative (loss of function) rather than positive == Investigations == === Canadian TIA Score === * Canadian Transient Ischemic Attack Score (see [https://www.mdcalc.com/calc/10421/canadian-transient-ischemic-attack-tia-score MDCalc]) * Categorizes them into low (<1%), me...") Tag: Visual edit
- 22:43, 6 November 2022 Aidan talk contribs created page Canadian Transient Ischemic Attack Score (Created page with "== Criteria == {| class="wikitable" !Item !Score |- ! colspan="2" |Clinical |- |First TIA in lifetime | +2 |- |Symptoms lasting 10 minutes or longer | +2 |- |History of carotid artery stenosis | +2 |- |Already on antiplatelet therapy | +3 |- |History of gait disturbance | +1 |- |History of unilateral weakness | +1 |- |History of vertigo | -3 |- |Initial triage DBP ≥110 mmHg | +3 |- |Dysarthria or aphasia on history of examination | +1 |- ! colspan="2" |ED Investiga...") Tag: Visual edit
- 22:31, 6 November 2022 Aidan talk contribs created page TIA (Redirected page to Transient ischemic attack and minor stroke) Tags: New redirect Visual edit
- 22:31, 6 November 2022 Aidan talk contribs created page TIMS (Redirected page to Transient ischemic attack and minor stroke) Tags: New redirect Visual edit
- 22:24, 6 November 2022 Aidan talk contribs created page Roux-en-Y gastric bypass (Created page with "* May decrease absorption of β-lactam and macrolide antibiotics, but fluoroquinolones and linezolid are likely able to be used as normal<ref>Anvari S, Lee Y, Lam M, Doumouras AG, Hong D. The Effect of Bariatric Surgery on Oral Antibiotic Absorption: a Systematic Review. ''Obes Surg''. 2020 Aug;30(8):2883-2892. doi: [https://doi.org/10.1007/s11695-020-04623-z 10.1007/s11695-020-04623-z]. PMID: [https://pubmed.ncbi.nlm.nih.gov/32314257/ 32314257].</ref> Category:Genera...") Tag: Visual edit
- 13:56, 6 November 2022 Aidan talk contribs created page Exercise-induced vasculitis (Created page with "* Small-vessel vasculitis * More common in women over 50 years * Primarily affects the lower legs, with petechial or urticarial rash, either itchy or painful ** Spares the foot and ankle compressed by socks * Triggered by strenuous exercise such as running or prolonged hiking, especially in the heat * Self-limited, resolving after a few days * Should rule out other vasculitides, autoimmune disorders, and coagulopathies * Can be treated with NSAIDs, topical steroids,...") Tag: Visual edit
- 13:32, 6 November 2022 Aidan talk contribs created page Harlequin syndrome (Created page with "== Background == * Rare dysautonomic syndrome * Caused by unilateral injury of sympathetic nerves * Often idiopathic, but may be caused by cervical or upper thoracic diseases === Etiologies === * Primary/idiopathic (Harlequin syndrome) * Secondary (Harlequin sign) ** Structural lesions: pancoast tumour, cervical sympathitic tumour, cervical carotid artery dissection, birth injury, thoracic syrinx, medullary infarction, thalamic hemorrhage ** Post-anaesthesia:...") Tag: Visual edit
- 12:57, 6 November 2022 Aidan talk contribs created page Frey syndrome (Created page with "== Background == * Caused by damage to the facial nerve most commonly from parotid gland surgery * Also called auriculotemporal syndrome == Clinical Manifestations == * Recurrent episodes of gustatory sweating in the distribution of the auriculotemporal nerve * May have associated flushing or erythema Category:Otolaryngology Category:Neurology") Tag: Visual edit
- 17:08, 2 November 2022 Aidan talk contribs created page Felty syndrome (Created page with "== Background == * Extraarticular manifestation of seropositive rheumatoid arthritis == Clinical Manifestations == * Triad of splenomegaly, neutropenia, and arthritis * Also anemia and thrombocytopenia Category:Rheumatology") Tag: Visual edit
- 17:02, 2 November 2022 Aidan talk contribs created page Erythema multiforme (Created page with "== Background == * Now considered a separate entity from Stevens-Johnson syndrome * More common in young adults, but can develop at any age * Classified as either: ** Minor: localized eruption with mild or no mucosal involvement ** Major: skin and mucosal erosions of raised atypical target lesions === Etiologies === * Drugs ** Antimicrobials *** Penicillins *** Tetracyclines *** Sulfonamides *** Azithromycin *** Antiretrovirals, particularly ...") Tag: Visual edit
- 16:55, 2 November 2022 Aidan talk contribs created page Mycobacterium haemophilum (Created page with "== Background == * One of the non-tuberculous mycobacteria * Grows at 30 ºC with iron in culture * Its environmental reservoir is water == Clinical Manifestations == * Tender erythematous skin nodules and ulcers * Tenosynovitis * Osteomyelitis == Management == * Treated with azithromycin and ciprofloxacin and rifampin, with or without amikacin") Tag: Visual edit
- 16:39, 2 November 2022 Aidan talk contribs created page Basidiobolus ranarum (Created page with "== Background == * Fungus within the order Order::Entomophthorales; previously classified as a member of the Zygomycetes * Mostly acquired in the USA (40% of cases, 90% of which are from Arizona) and Saudi Arabia (25%) * More common in men than women * Risk factors include diabetes mellitus and immunocompromise == Clinical Manifestations == === Cutaneous Disease === * A single enlarging, painless and firm swelling in soft tissues on extremities * May deve...") Tag: Visual edit
- 16:33, 2 November 2022 Aidan talk contribs created page Heinz body (Created page with "* RBC inclusion made of unstable hemoglobin molecules which suggests G6PD deficiency Category:Hematology") Tag: Visual edit
- 16:31, 2 November 2022 Aidan talk contribs created page Cabot ring (Created page with "* RBC inclusion body made up of the mitotic spindle that suggests myelodysplastic syndrome") Tag: Visual edit
- 16:31, 2 November 2022 Aidan talk contribs created page Pappenheimer body (Created page with "* RBC inclusion body made of iron that suggests sideroblastic anemia Category:Hematology") Tag: Visual edit
- 16:30, 2 November 2022 Aidan talk contribs created page Basophilic stippling (Created page with "* RBC inclusion body made of RNA that suggests lead toxicity Category:Hematology") Tag: Visual edit
- 16:30, 2 November 2022 Aidan talk contribs created page Howell-Jolly body (Created page with "* RBC inclusion body made of DNA that suggests asplenia Category:Hematology") Tag: Visual edit
- 16:29, 2 November 2022 Aidan talk contribs created page Duffy-null associated neutrophil count (Created page with "== Background == * Previously known as benign ethnic neutropenia * Polymorphisms in ACKR1 gene, which encodes Duffy antigen receptor for chemokines (DARC) * The mutations lead to neutrophils leaving circulation for tissue, resulting in lower peripheral blood neutrophil counts * The gene mutation is present in about 60 to 70% of people with African ancestry, and may have evolved to impair entry of Plasmodium vivax into RBCs * About 10% of people with DANC will have a...") Tag: Visual edit
- 16:24, 2 November 2022 Aidan talk contribs created page Benign ethnic neutropenia (Redirected page to Duffy-null associated neutrophil count) Tags: New redirect Visual edit
- 16:24, 2 November 2022 Aidan talk contribs created page Cronkhite-Canada syndrome (Created page with "== Clinical Manifestations == * Diarrhea, alopecia, gastrointestinal hamartomatous plypopsis, onychodystrophy, hyperpigmentation == Investigations == * Often have positive ANA and elevated IgG4 levels == Differential Diagnosis == * Juvenile polyposis * Cowden disease * Bannayan-Riley-Ruvalcaba syndrome * Peutz-Jeghers syndrome") Tag: Visual edit
- 16:17, 2 November 2022 Aidan talk contribs created page Osler-Weber-Rendu disease (Redirected page to Hereditary hemorrhagic telangiectasia) Tags: New redirect Visual edit
- 17:34, 1 November 2022 Aidan talk contribs created page Granulomatous disease (Created page with "== Background == * Granulomatous inflammation is chronic inflammation that involves macrophages and T lymphocytes to wall off an infectious organism * T cells are activated and in turn activate macrophages, which undergo morphological changes to become more epithelioid * Creates two main types of granulomas: foreign body granulomas, and immune ganulomas ** In immune granulomas, macrophages active T cells to produce IL-2 == Differential Diagnosis == * Tuberculosis...") Tag: Visual edit
- 14:26, 27 October 2022 Aidan talk contribs created page Gut microbiota (Created page with "==Background== * The gastrointestinal tract is normally colonized with a number of microbes * Comprised of an estimated 35,000 bacterial species * Bacteria are generally either in the phyla Bacteroidetes or Firmicutes * The gut flora are impacted by: ** Mode of delivery at birth (Cesarean section versus vaginal delivery) ** Diet during infancy (breast milk versus formula) ** Diet during adulthood (plant-based or meat-based) ** Use of antimicrobials * May play a r...")
- 14:17, 27 October 2022 Aidan talk contribs created page Lacticaseibacillus paracasei (Created page with "* Stain::Gram-positive Shape::bacillus * Member of gut microflora {{DISPLAYTITLE:''Lacticaseibacillus paracasei}} Category:Gram-positive bacilli Category:Gut microbiota")
- 14:15, 27 October 2022 Aidan talk contribs created page Remdesivir (Created page with "==Background== * Direct antiviral * Indicated for SARS-CoV-2 and possibly Ebolavirus infections ==Dosing== ===COVID-19=== * Early treatment of mild disease patients at high risk of progression (within 7 days of onset): 200 mg IV on day 1 followed by 100 mg IV daily for 2 days * Treatment of moderate disease newly on low-flow oxygen: 200 mg IV on day 1 followed by 100 mg IV daily for 4 days Category:Antivirals")
- 02:09, 23 October 2022 Aidan talk contribs created page Antiviral spectrum of activity (Created page with "{| class="wikitable" !Medications !CMV !EBV !HHV-6 !HHV-8 !HSV !VZV !BKV !Adeno |- |acyclovir/valacyclovir/famciclovir |± | | | | + | + | | |- |ganciclovir/valganciclovir | + | | + |± | + | + | | |- |foscarnet | + | | + |± | + | + | | |- |cidofovir | + | | + |± | + | + |– |± |- |letermov...") Tag: Visual edit
- 14:09, 19 October 2022 Aidan talk contribs created page Ceftin (Redirected page to Cefuroxime) Tags: New redirect Visual edit
- 16:42, 18 October 2022 Aidan talk contribs created page Antimicrobials in breastfeeding (Created page with "== Antibiotics == * Safest antibiotics in breastfeeding are penicillins, cephalosporins, and carbapenems, as well as macrolides * Metronidazole is debatable, but generally considered safe * Fluoroquinolones are expressed in high enough levels in the breast milk, but risks may outweigh benefits in some situations * Tetracyclines are excreted in low amounts in breast milk, but are usually avoided due to concerns about effects on bone growth or...") Tag: Visual edit
- 02:04, 18 October 2022 Aidan talk contribs created page Septic pelvic thrombophlebitis (Created page with "== Background == * Septic thrombophlebitis of the pelvic veins * Typically occurs a few days to a week after delivery * Rarely occurs in non-pregnant people, associated with pelvic infections (such as pelvic inflammatory disease), surgery (such as hysterectomy), uterine fibroids, hormonal stimulation with gonadotropins, or malignancy == Clinical Manifestations == * Postpartum or postoperative fever lasting more than 3-4 days despite appropriate antibiotics...") Tag: Visual edit
- 01:44, 18 October 2022 Aidan talk contribs created page ASA Physical Status Classification System (Created page with "{| class="wikitable" !ASA PS Classification !Definition !Adult Examples !Pediatric Examples !Obstetric Examples |- !ASA I |A normal healthy patient |Healthy, non-smoking, no or minimal alcohol use |Healthy (no acute or chronic disease), normal BMI percentile for age | |- !ASA II |A patient with mild systemic disease |Mild diseases only without substantive functional limitations. Current smoker, social alcohol drinker, pregnancy, obesity (30<BMI<40), well-controlled DM/HT...") Tag: Visual edit: Switched
- 17:37, 11 October 2022 Aidan talk contribs moved page Candidal endocarditis to Fungal endocarditis
- 14:28, 11 October 2022 Aidan talk contribs created page Cosentyx (Redirected page to Secukinumab) Tags: New redirect Visual edit
- 02:27, 10 October 2022 Aidan talk contribs created page Angioimmunoblastic T-cell lymphoma (Created page with "== Background == * Subtype of mature peripheral T-cell lymphoma * Previously also known as angioimmunoblastic lymphadenopathy with dysproteinemia, immunoblastic lymphadenopathy, and lymphogranulomatosis X * Accounts for 1 to 2% of non-Hodgkin lymphoma * Derives from follicular T helper (T<sub>FH</sub>) cells == Clinical Manifestations == * Myriad and often non-specific, resulting in delayed diagnoses * Usually advanced stage at diagnosis * Most common symptoms are...") Tag: Visual edit
- 13:30, 6 October 2022 Aidan talk contribs created page Leukocyte adhesion deficiency (Created page with "* A primary immunodeficiency * Autosomal recessive * May be either type 1 with mutation in an integrin, or type 2 with a mutation in a ligand for selectins Category:Immunology Category:Primary immunodeficiencies") Tag: Visual edit
- 02:04, 4 October 2022 Aidan talk contribs created page CAP (Redirected page to Community-acquired pneumonia) Tags: New redirect Visual edit
- 01:11, 4 October 2022 Aidan talk contribs created page CSD (Redirected page to Bartonella henselae) Tags: New redirect Visual edit
- 15:04, 2 October 2022 Aidan talk contribs created page PAM (Created page with "* Treatment for Helicobacter pylori infection * Regimen is 14 days of: ** PPI: esomeprazole 20 mg p.o. daily (or lansoprazole 30 mg, omeprazole 20 mg, pantoprazole 40 mg, or rabeprazole 20 mg) ** Amoxicillin 1000 mg p.o. BID ** Metronidazole 500 mg p.o. TID to QID Category:Medications") Tag: Visual edit
- 15:03, 2 October 2022 Aidan talk contribs created page PAR (Created page with "* Treatment for Helicobacter pylori infection * Regimen is 10 days of: ** PPI: esomeprazole 20 mg p.o. daily (or lansoprazole 30 mg, omeprazole 20 mg, pantoprazole 40 mg, or rabeprazole 20 mg) ** Amoxicillin 1000 mg p.o. BID ** Rifabutin 150 mg p.o. BID Category:Medications") Tag: Visual edit
- 15:02, 2 October 2022 Aidan talk contribs created page PAL (Created page with "* Treatment for Helicobacter pylori infection * Regimen is 14 days of: ** PPI: esomeprazole 20 mg p.o. daily (or lansoprazole 30 mg, omeprazole 20 mg, pantoprazole 40 mg, or rabeprazole 20 mg) ** Amoxicillin 1000 mg p.o. BID ** Levofloxacin 500 mg p.o. daily Category:Medications") Tag: Visual edit
- 15:00, 2 October 2022 Aidan talk contribs created page PAC (Created page with "Category:Medications")
- 14:59, 2 October 2022 Aidan talk contribs created page CLAMET Quad (Redirected page to PAMC) Tag: New redirect
- 14:58, 2 October 2022 Aidan talk contribs created page BMT Quad (Redirected page to PBMT) Tags: New redirect Visual edit
- 14:58, 2 October 2022 Aidan talk contribs created page PAMC (Created page with "* Treatment for Helicobacter pylori infection * Regimen is 14 days of: ** PPI: esomeprazole 20 mg p.o. daily (or lansoprazole 30 mg, omeprazole 20 mg, pantoprazole 40 mg, or rabeprazole 20 mg) ** Amoxicillin 1000 mg p.o. BID ** Metronidazole 500 mg p.o. TID to QID ** Clarithromycin 500 mg p.o. BID Category:Medications") Tag: Visual edit