Antimicrobials in breastfeeding

From IDWiki

Antibiotics

  • Safest antibiotics in breastfeeding are penicillins, cephalosporins, and carbapenems, as well as macrolides
  • Metronidazole is debatable, but generally considered safe
  • Fluoroquinolones are expressed in high enough levels in the breast milk, but risks may outweigh benefits in some situations
  • Tetracyclines are excreted in low amounts in breast milk, but are usually avoided due to concerns about effects on bone growth or dental staining
  • Fluoroquinolones are generally avoided, since they are excreted in high enough levels to be of concern and are associated with arthropathis in immature animal models
  • Sulfonamides such as co-trimoxazole are generally avoided when the breastfeeding infant is less than 1 month old due to risk of jaundice/kernicterus, but is otherwise considered generally safe