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- 02:51, 27 September 2022 Aidan talk contribs created page Venclyxto (Redirected page to Venetoclax) Tags: New redirect Visual edit
- 02:50, 27 September 2022 Aidan talk contribs created page Venclexta (Redirected page to Venetoclax) Tags: New redirect Visual edit
- 02:49, 27 September 2022 Aidan talk contribs created page Venetoclax (Created page with "* Medication indicated for the treatment of AML and small lymphocytic lymphoma * Inhibits Bcl-2 * Adverse effects include neutropenia, diarrhea, nausea, anemia, and fatigue * Relatively high risk of invasive fungal infection when combined with azacitadine for treatment of AML Category:Medications") Tag: Visual edit
- 02:43, 27 September 2022 Aidan talk contribs created page Capnocytophaga canimorsus (Created page with "== Background == === Microbiology === * Stain::Gram-negative Shape::bacillus in the genus Genus::Capnocytophaga * May be fusiform and curved * Grows slowly on standard media * Capnophilic, preferring high CO<sub>2</sub> * Oral flora of dogs (60-70%) and cats (15-55%) === Risk Factors === * Risk factors for severe disease include asplenia and alcoholism == Clinical Manifestations == * Infections usually occur after penetrative inoculation from a...") Tag: Visual edit
- 02:31, 27 September 2022 Aidan talk contribs created page Capnocytophaga (Created page with "{{DISPLAYTITLE:''Capnocytophaga''}} * Genus of Stain::Gram-negative fusiform bacilli ** One rounded end and one tapered end ** Occasionally filamentous, occasionally curved * Fastidious and capnophilic * Members of the normal oral flora of humans and other vertebrates including dogs and cats * Species include: ** Capnocytophaga gingivalis, Capnocytophaga ochracea, and Capnocytophaga sputigena, which are associated with periodontal dis...") Tag: Visual edit
- 18:25, 26 September 2022 Aidan talk contribs created page Burning mouth syndrome (Created page with "* Syndrome of chronic oral pain * Mostly affects perimenopausal or postmenopaulsa women * Pathophysiology thought to be neuropathic * Pain is characterized as burning of oral mucosa, and may have associated dysgeusia, paresthesia, dysesthesia, and xerostomia * Treatments include alpha-lipoic acid (ALA) supplementation, topical clonazepam, gabapentin, combination ALA and gabapentin, Catauma, or bupivacaine")
- 14:21, 26 September 2022 Aidan talk contribs created page Trichophyton mentagrophytes (Created page with "{{DISPLAYTITLE:''Trichophyton mentagrophytes''}} == Background == * Dermatophyte associated with rodents or other companion animals == Clinical Manifestations == * Tinea corporis == Management == * Probably topical azoles, itraconazole, or terbinafine Category:Dermatophytes") Tag: Visual edit
- 13:58, 26 September 2022 Aidan talk contribs created page Actemra (Redirected page to Tocilizumab) Tag: New redirect
- 09:29, 23 September 2022 Aidan talk contribs created page Multidrug-resistant organism (Created page with "== Background == * Microorganisms, predominantly bacteria, that are resistant to one or more classes of antimicrobial agents * Definition varies from hospital to hospital or country to country * Includes the following bacteria: ** Gram-positives *** MRSA *** VRE *** Multidrug-resistant Streptococcus pneumoniae ** Gram-negatives: *** ESBL and CPE *** Acinetobacter baumannii complex *** Stenotrophomonas maltophilia *** Burkholderia cepacia ***...") Tag: Visual edit
- 11:46, 22 September 2022 Aidan talk contribs created page Antibiotic spectrum index (Created page with "* Measures the spectrum of an antibiotic, with a range from 0 to 14 * One point for activity against each of the following: ** Methicillin-sensitive Staphylococcus aureus (MSSA) ** Methicillin-resistant S. aureus (MRSA) ** Enterococcus faecalis ** Vancomycin-resistant Enterococcus faecalis (VRE) ** Escherichia coli and Klebsiella ** ampC producers ** Extended-spectrum β-lactamase (ESBL) E. coli/Klebsiella ** Pseudomonas aeruginosa ** Penicillin-resistant pneumococcus (P...")
- 00:56, 18 September 2022 Aidan talk contribs moved page APL to Acute promyelocytic leukemia
- 14:22, 16 September 2022 Aidan talk contribs created page TMA (Redirected page to Thrombotic microangiopathy) Tags: New redirect Visual edit
- 14:49, 14 September 2022 Aidan talk contribs created page Plasma cell granuloma (Created page with "* Rare benign inflammatory pseudotumour * May be on the spectrum of IgG4 disease * Most commonly occurs in the lungs, but can also present in brain, kidney, stomach, heart, and other organs Category:Rheumatology Category:Oncology Category:Hematology")
- 13:03, 8 September 2022 Aidan talk contribs created page ANCA-associated vaculitis (Created page with "* Category of small-vessel vasculitis associated with antineutrophil cytoplasmic antibodies * Often have palpable purpura * Includes: ** Microscopic polyangiitis: anti-MPO/p-ANCA; pulmonary-renal syndrome ** Granulomatosis with polyangiitis: anti-PR3/c-ANCA; pulmonary-renal syndrome ** Eosinophilic granulomatosis with polyangiitis: more often anti-MPO; rhinosinusitis, asthma, eosinophilia, glomerulonephritis Cate...") Tag: Visual edit
- 13:01, 8 September 2022 Aidan talk contribs created page Antineutrophil cytoplasmic antibody (Created page with "* Antibodies associated with certain types of vasculitis * Previously classified based on intracellular distribution as cytoplasmic (c-ANCA) or perinuclear (p-ANCA) * Now classified by target antigens ** Anti-myeloperoxidase antibodies (MPO-ANCA), previously known as p-ANCA, and associated with microscopic polyangiitis and Churg-Strauss syndrome ** Antiproteinase-3 antibodies (PR3-ANCA), previously known as c-ANCA, and associated wit...") Tag: Visual edit
- 12:58, 8 September 2022 Aidan talk contribs created page ANCA (Redirected page to Antineutrophil cytoplasmic antibody) Tags: New redirect Visual edit
- 18:43, 6 September 2022 Aidan talk contribs created page Rothia (Created page with "{{DISPLAYTITLE:''Rothia''}} == Background == * Genus of Stain::Gram-positive coccobacilli that can form filamentous branches * Normal oral flora in humans * Associated with dental caries and periodontal disease * Species of importance include: ** Rothia mucilaginosa (most common cause of disease in humans) ** Rothia dentocariosa ** Rothia aeria ** Rothia nasimurium ** Rothia amarae * Risk factors for infection include im...") Tag: Visual edit
- 13:35, 6 September 2022 Aidan talk contribs created page Gram-positive coccobacilli (Created page with "==Common Bacteria== * Appearance of bacteria can be changed by recent antibiotic use * If no recent beta-lactams: ** Haemophilus ** Aggregatibacter ** Acinetobacter ** Kingella ** Pasteurella ** Francisella ** Bordatella ** Yersinia ** Coxiella ** Brucella ==List of Bacteria== {{#ask: Stain::Gram-positive Shape::coccobacillus |?Stain |?Cellular shape }} [[Category::Gram-positive bacteria]]") Tag: Visual edit: Switched
- 01:07, 4 September 2022 Aidan talk contribs created page Diagnostic stewardship of urine cultures (Created page with "== Background == * Asymptomatic bacteriuria is common, but positive urine cultures are still often inappropriately treated * The process of inappropriately treating asymptomatic bacteriuria can be interrupted at the culture collection stage == Interventions == === Urine Culture Ordering === * The following practices are recommended: ** Require documentation of signs or symptoms of UTI to obtain a urine culture, including dysuria or flank pain *** Patients without...") Tag: Visual edit
- 00:56, 4 September 2022 Aidan talk contribs created page Asymptomatic bacteriuria (Created page with "== Background == * Bacteria growing in urine culture without evidence of infection * Common, especially in older patients == Management == * Only requires treatment in pregnancy (see Asymptomatic bacteriuria in pregnancy) and prior to invasive urological procedures * Sometimes done for renal transplant patients, but overall evidence likely favours harm * See also Diagnostic stewardship of urine cultures for approaches to reducing inappropriate collection of u...") Tag: Visual edit
- 16:44, 31 August 2022 Aidan talk contribs moved page Rhodococcus equi to Rhodococcus hoagii (bug renamed)
- 20:17, 30 August 2022 Aidan talk contribs created page Category:Lincosamides (Created page with "Category:Antibiotics") Tag: Visual edit
- 20:17, 30 August 2022 Aidan talk contribs created page Clindamycin (Created page with "== Background == * Reversibly binds the 50S ribosomal subunit, thereby preventing protein synthesis * Spectrum of activity includes gram-positives and anaerobes == Dosing == * Adjunctive for severe infections: 600 mg IV q8h or 450 mg p.o. q8h for 5 days Category:Lincosamides") Tag: Visual edit
- 18:46, 30 August 2022 Aidan talk contribs created page Cloxacillin (Created page with "== Dosing == * Standard: 2 g IV q6h * High dose (for critical illness, IE, or CNS penetration: 2 g IV q4h β-lactams") Tag: Visual edit
- 18:19, 30 August 2022 Aidan talk contribs created page ESC 2015 modified criteria for the diagnosis of infective endocarditis (Created page with "== Background == * Used to diagnose infective endocarditis * Recommended when the modified Duke criteria are possible or rejected, but with high clinical suspicion ** Repeat the echo ** Look for imaging evidence of embolic phenomena, such as MRI brain, whole body CT, or PET/CT ** Consider specialized imaging like cardiac CT, PET/CT, or white cell SPECT/CT * Compared to modified Duke criteria, the ESC criteria add the following: ** Paravalvular lesions detect...") Tag: Visual edit
- 13:59, 30 August 2022 Aidan talk contribs created page Aconite poisoning (Created page with "* Toxic alkaloid derived from monkshood, wolfsbane, and other members of the genus Aconitum * Bins and opens sodium channels, preventing their inactivation * Manifestations include GI (nausea, vomiting, cramping), neurologic (numbness, particularly of face and mouth then progressing to limbs, muscle weakness, and coma), and cardiac (hypotension, arrhythmias) * Management is supportive ** Bradycardia: atropine ** Long QT/TdP: magniseium ** Arrhythmias: cardioversion ** EC...") Tag: Visual edit
- 13:41, 30 August 2022 Aidan talk contribs created page (1,3)-β-D-glucan (Created page with "* Polysaccharide component of many fungal cell walls * Used to diagnose invasive fungal infection * False positives are possible due to antibiotics, bacteremia, enterocolitis, cellulose dialysis filters, or surgical gauzes, as well as blood products including IVIG Category:Investigations") Tag: Visual edit
- 13:38, 30 August 2022 Aidan talk contribs created page Β-D glucan (Redirected page to (1,3)-β-D-glucan) Tags: New redirect Visual edit
- 12:43, 30 August 2022 Aidan talk contribs created page Cystitis (Redirected page to Urinary tract infection) Tags: New redirect Visual edit
- 13:51, 27 August 2022 Aidan talk contribs moved page Legionella species to Legionella without leaving a redirect
- 13:51, 27 August 2022 Aidan talk contribs deleted page Legionella (Deleted to make way for move from "Legionella species")
- 12:38, 25 August 2022 Aidan talk contribs created page Tecovirimat (Created page with "== Dosing == * 13 to ≤25 kg: 200 mg p.o. twice daily for 14 days * 25 to ≤40 kg: 400 mg p.o. twice daily for 14 days * ≥40 kg: 600 mg p.o. twice daily for 14 days Category:Medications") Tag: Visual edit
- 18:45, 17 August 2022 Aidan talk contribs created page Lemmel syndrome (Created page with "* Obstructive jaundice caused by a periampullary duodenal diverticulum that compresses the intrapancreatic common bile duct Category:Gastroenterology") Tag: Visual edit
- 17:07, 17 August 2022 Aidan talk contribs created page Paenibacillus (Created page with "==Background== ===Microbiology=== * Genus of Stain::Gram-positive bacilli * Closely related to Bacillus (the Latin name means "almost Bacillus") * The more common species that have been isolated from humans include: ** Paenibacillus phoenicis ** Paenibacillus lautus * Many other species are also occasionally isolated ==Clinical Manifestations== * Common cause of blood culture contamination * However, can be a true pathogen ==Managem...")
- 14:24, 17 August 2022 Aidan talk contribs created page Asplenia and hyposplenia (Created page with "== Background == * Spleen is an important part of the immune system, particularly for encapsulated organisms * Increased risk for severe sepsis * Particularly increased risk for infection with: ** Streptococcus pneumoniae ** Haemophilus influenzae ** Neisseria meningitidis ** Capnocytophaga ** Bordatella holmesii ** Babesia ** Plasmodium falciparum == Management == * Cornerstone of management is prevention with vaccination ** Refer to Imm...") Tag: Visual edit
- 14:19, 17 August 2022 Aidan talk contribs created page Asplenia (Redirected page to Asplenia and hyposplenia) Tags: New redirect Visual edit
- 13:04, 15 August 2022 Aidan talk contribs created page Brachyspira pilosicoli (Redirected page to Intestinal spirochetosis) Tags: New redirect Visual edit
- 13:04, 15 August 2022 Aidan talk contribs created page Brachyspira aalborgi (Redirected page to Intestinal spirochetosis) Tags: New redirect Visual edit
- 16:03, 5 August 2022 Aidan talk contribs created page Splenic granuloma (Created page with "== Background == * Common incidental finding on abdominal imaging == Differential Diagnosis == * Granulomas ** Tuberculosis ** Histoplasmosis ** Less commonly ''Pneumocystis carinii'' and brucellosis ** Sarcoidosis * Other causes of splenic calcifications include: ** Diffuse calcifications *** Phleboliths *** Amyloidosis *** Candidiasis *** Non-tuberculous mycobacteria *** Sickle cell disease *** Hodgkin lymphoma (following trea...") Tag: Visual edit
- 15:12, 4 August 2022 Aidan talk contribs created page Autoimmune polyendocrinopathy, candidiasis, and ectodermal dystrophy (Created page with "== Background == * Autosomal recessive genetic syndrome resulting from mutation of the ''AIRE'' gene == Clinical Manifestations == * Onset usually in the first 10 to 20 years of life * Hypoparathyroidism is the most common endocrine finding ** Addison disease, and ovarian failure are the next most common endocrine disorders ** Can also have diabetes mellitus and hypothyroidism * Alopecia is common, as well as tooth enamel hypoplasia, nail dystrophy...") Tag: Visual edit
- 15:07, 4 August 2022 Aidan talk contribs created page APECED (Redirected page to Autoimmune polyendocrinopathy, candidiasis, and ectodermal dystrophy) Tags: New redirect Visual edit
- 13:04, 4 August 2022 Aidan talk contribs moved page Lactobacillus species to Lactobacillus without leaving a redirect
- 13:04, 4 August 2022 Aidan talk contribs deleted page Lactobacillus (content was: " {{DISPLAYTITLE:''Lactobacillus''}}", and the only contributor was "Aidan" (talk))
- 22:28, 3 August 2022 Aidan talk contribs created page Nasal septal perforation (Created page with "== Differential Diagnosis == * Trauma ** Surgical complications ** Rhinotillexomania (nose-picking) ** Foreign object * Drugs ** Recreational: cocaine, methamphetamines, ketamine ** Therapeutic: vasoconstrictors, intranasal corticosteroids, bevacizumab ** Other: soda ash, metal exposure (copper, arsenic, chromium, nickel) * Neoplasms ** Nasal carcinoma ** Multiple myeloma ** Non-Hodgkin lymphoma ** NK cell lymphoma * Rheumatol...") Tag: Visual edit
- 12:36, 1 August 2022 Aidan talk contribs created page Recurrent urinary tract infection (Created page with "== Background == * At least 2 UTIs (with cultures) in 6 months or 3 in 12 months * Most common in postmenopausal women == Management == * Acute treatment of urinary tract infection for each episode * Assess for red flags that may warrant further assessment, including pelvic mass, vaginal prolapse beyond the hymen, rectal prolapse, nephrolithiasis, chronic catheterization, immunosuppression, atypical symptoms (eg, gross hematuria, pneumaturia following...") Tag: Visual edit
- 16:47, 28 July 2022 Aidan talk contribs created page Antimicrobial stewardship program (Created page with "== Background == * Program to ensure that antimicrobials are used appropriately, in order to improve patient outcomes == Core Elements == * Senior hospital management leadership towards antimicrobial stewardship * Accountability and responsibilities * Available expertise on infection management * Education and practical training * Other actions aiming at responsible antimicrobial use * Monitoring and surveillance * Reporting and feedback") Tag: Visual edit
- 16:39, 28 July 2022 Aidan talk contribs moved page Infection Prevention and Control to Infection prevention and control program without leaving a redirect
- 14:02, 24 July 2022 Aidan talk contribs created page Blue sclerae (Created page with "== Differential Diagnosis == * Osteogenesis imperfecta * Scleritis (especially from rheumatoid arthritis), caused by immune complex deposition * High intraocular pressure, caused by thinning of the sclera * Congenital melanosis oculi, caused by pigmentation of the uvea") Tag: Visual edit
- 03:11, 24 July 2022 Aidan talk contribs created page β-lactam-associated neutropenia (Created page with "{{DISPLAYTITLE:β-lactam-associated neutropenia}} == Background == * Adverse reaction to β-lactam antibiotics occurring in about 1 to 10% of prolonged courses * Higher risk with penicillin G, nafcillin, oxacillin, piperacillin-tazobactam, ceftriaxone, and ceftaroline * Risk increases with cumulative exposure * Mechanism is unclear; may be some combination of a direct toxic effect or an Hypersensitivity reaction|immune-mediated...") Tag: Visual edit
- 17:26, 22 July 2022 Aidan talk contribs created page Group G Streptococcus (Redirected page to Streptococcus dysgalactiae subspecies equisimilis) Tags: New redirect Visual edit