Splenic granuloma

Background

• Common incidental finding on abdominal imaging

Differential Diagnosis

• Granulomas
  • Tuberculosis
  • Histoplasmosis
  • Rarely Pneumocystis carinii, brucellosis, or melioidosis
  • Sarcoidosis
• Other causes of splenic calcifications include:
  • Diffuse calcifications
    • Phleboliths
    • Amyloidosis
    • Candidiasis
    • Non-tuberculous mycobacteria
    • Sickle cell disease
    • Hodgkin lymphoma (following treatment)
    • Rarely, lupus, cat scratch disease, and hepatosplenic anthrasilicosis
  • Calcified splenic lesions
    • Hemangioma
    • Lymphangioma
    • Calcified splenic arterial aneurysm
    • Hydatid cyst
    • Post-traumatic splenic cyst
    • Epidermoid cyst
    • Dermoid cyst
    • Splenic infarct
    • Congenital cyst

Further Reading

• Nikita Consul, Sidra Javed-Tayyab, Chandana Lall, Corey T. Jensen, Christine O. Menias, Perry J. Pickhardt, and Khaled M. Elsayes. Calcified Splenic Lesions: Pattern Recognition Approach on CT With Pathologic Correlation. Am J Roentgenology. 2020;214(5):1083-1091. doi: 10.2214/AJR.19.22246