(1,3)-β-D-glucan

• Polysaccharide component of many fungal cell walls
• Used to diagnose invasive fungal infection, particularly Pneumocystis jirovecii and hepatosplenic candidiasis
  • Also positive with histoplasmosis
• False positives are possible due to antibiotics, bacteremia, enterocolitis, cellulose dialysis filters, or surgical gauzes, as well as blood products including IVIG