Antineutrophil cytoplasmic antibody
From IDWiki
- Antibodies associated with certain types of vasculitis
- Previously classified based on intracellular distribution as cytoplasmic (c-ANCA) or perinuclear (p-ANCA)
- Now classified by target antigens
- Anti-myeloperoxidase antibodies (MPO-ANCA), previously known as p-ANCA, and associated with microscopic polyangiitis and Churg-Strauss syndrome
- Antiproteinase-3 antibodies (PR3-ANCA), previously known as c-ANCA, and associated with granulomatosis with polyangiitis
