Infection control precautions by disease

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Disease Organisms Type of precautions Duration Notes
Abscess (with significant drainage) various Contact Until drainage controlled
Abscess (no significant drainage) various Routine
Amoebiasis Entamoeba histolytica Routine Rarely transmitted person-to-person
Actinomycosis Actinomyces Routine Not transmitted person-to-person
Anthrax Bacillus anthracis Routine
Anthrax (cutaneous) Bacillus anthracis Routine Contact precautions if significant drainage
Anthrax (pulmonary) Bacillus anthracis Routine Not transmitted person-to-person
Arthropod-borne viral encephalitis Eastern equine encephalitis Routine Not transmitted person-to-person
western equine encephalitis Contact Not transmitted person-to-person
Venezuelan equine encephalitis Contact Not transmitted person-to-person
St. Louis encephalitis Contact Not transmitted person-to-person
California encephalitis Contact Not transmitted person-to-person
West Nile virus Contact Not transmitted person-to-person
not otherwise specified Contact Not transmitted person-to-person
Arthropod-borne viral fever Dengue virus Routine Not transmitted person-to-person
Yellow fever virus Contact Not transmitted person-to-person
Colorado tick fever virus Contact Not transmitted person-to-person
not otherwise specified Contact Not transmitted person-to-person
Ascariasis Ascaris lumbricoides Routine Not transmitted person-to-person
Aspergillosis Aspergillus Routine Can consider contact or airborne if large draining infection requiring repeat irrigations
Babesiosis Babesia microti Routine Not transmitted person-to-person
Blastomycosis Blastomyces dermatitidis Routine Not transmitted person-to-person
Botulism Clostridium botulinum Routine Not transmitted person-to-person
Botulism (food poisoning) Clostridium botulinum Routine
Bronchiolitis various Contact Duration of illness
Brucellosis Brucella melitensis Routine Not transmitted person-to-person
Burn infection Staphylococcus aureus Contact Until drainage stops or is controlled
Candidiasis Candida Routine
Cat-scratch fever Bartonella henselae Routine Not transmitted person-to-person
Cellulitis various Routine
Chancroid Haemophilus ducreyi Routine Sexually transmitted
Chickenpox Varicella-zoster virus Refer to Varicella
Chlamydia pneumoniae Routine
Cholera Vibrio cholerae Refer to Gastroenteritis
Clostridium difficile Clostridium difficile Contact Duration of illness
Coccidioidomycosis Coccidioides immitis Routine Not transmitted person-to-person
Congenital rubella Rubella virus Contact Until 1 year of age Routine precautions if nasopharyngeal and urine cultures are repeatedly negative after 3 months of age
Conjunctivitis Adenovirus Refer to specific syndrome (conjunctivitis)
Chlamydia trachomatis Routine
bacterium, not otherwise specified Routine
virus, not otherwise specified Contact Duration of illness Highly contageous
Creutzfeldt-Jakob disease Prions Routine
Croup various Refer to Respiratory infections in infants and young children
Cryptococcosis Cryptococcus Routine Not transmitted person-to-person
Cryptosporidiosis Cryptosporidium Refer to Gastroenteritis
Cystic fibrosis various Contact Not transmitted person-to-person
Cysticercosis Taenia solium Routine Not transmitted person-to-person
Cytomegalovirus Cytomegalovirus Routine
Dengue Dengue virus Routine Not transmitted person-to-person
Diphtheria (cutaneous) Corynebacterium diphtheriae Contact Until completed treatment and cultures negative Two cultures 24 hours apart
Diphtheria (pharyngeal) Corynebacterium diphtheriae Droplet Until completed treatment and cultures negative Two cultures 24 hours apart
Echinococcosis Echinococcus Routine
Encephalitis Herpes simplex virus Routine
Encephalitis or encephalomyelitis various Refer to specific organism
Endometritis Streptococcus pyogenes Routine
Endometritis various Routine
Epiglottitis Haemophilus influenzae type b Droplet 24 hours of effective therapy
Food poisoning Clostridium botulinum Routine Not transmitted person-to-person
Clostridium perfringens Routine
Clostridium perfringens Contact Not transmitted person-to-person
Staphylococcus aureus Contact Not transmitted person-to-person
Furunculosis Staphylococcus aureus Routine Consider Contact precautions if uncontrolled drainage
Furunculosis (infants and young children) Staphylococcus aureus Contact Until no longer draining
Gangrene various Routine
Gas gangrene Clostridium perfringens Routine Rarely transmitted person-to-person
Gastroenteritis Adenovirus Refer to Gastroenteritis
Campylobacter Refer to Gastroenteritis
Coxsackievirus Refer to Enterovirus
Echovirus Refer to Enterovirus
Enterovirus Routine
Escherichia coli Refer to Gastroenteritis
Giardia lamblia Refer to Gastroenteritis
Norovirus Contact 48 hours after resolution of symptoms
Rotavirus Contact Duration of illness
Shigella Refer to Gastroenteritis
Vibrio cholerae Refer to Gastroenteritis
Vibrio parahaemolyticus Refer to Gastroenteritis
Vibrio vulnificus Refer to Gastroenteritis
Yersinia enterocolitica Refer to Gastroenteritis
Gastroenteritis (continent) not otherwise specified Routine
Gastroenteritis (diapered or incontinent) Enterovirus Contact Duration of illness
not otherwise specified Contact Duration of illness
Gastritis Helicobacter pylori Routine
Gonococcal ophthalmia neonatorum Neisseria gonorrhoeae Routine
Gonorrhea Neisseria gonorrhoeae Routine
Granuloma inguinale Klebsiella granulomatis Routine
Guillain-Barré syndrome Routine Not an infectious disease
Hantavirus pulmonary syndrome Hantavirus Routine Not transmitted person-to-person
Herpes (disseminated, primary, or severe) Herpes simplex virus Contact Until lesions dry and crusted
Herpes (mucocutaneous recurrent) Herpes simplex virus Routine
Herpes (neonatal) Herpes simplex virus Contact Until lesions dry and crsted
Hookworm various Routine
Histoplasmosis Histoplasma capsulatum Routine Not transmitted person-to-person
HIV HIV Routine Sexually transmitted
Impetigo Staphylococcus aureus Contact 24 hours of effective therapy
Infectious mononucleosis and other syndromes Epstein-Barr virus Routine
Infectious mononucleosis Cytomegalovirus Routine
Influenza (seasonal) Influenza virus Droplet 7 days after onset or 24 hours asymptomatic (whichever longer)
Influenza (avian) Influenza virus
Influenza (pandemic) Influenza virus Droplet
Invasive Group A streptococcal disease Streptococcus pyogenes Droplet 24 hours of effective therapy
Kawasaki syndrome Routine Not infectious
Legionellosis Legionella Routine Not transmitted person-to-person
Leprosy Mycobacterium leprae Routine
Leptospirosis Leptospira Routine Not transmitted person-to-person
Lice (head) Pediculus humanus humanus Contact Until 24 hours of effective therapy
Lice (body) Pediculus humanus capitis Routine Transmitted through clothing, so consider Contact precautions when undressing patient
Lice (pubic) Pthirus pubis Routine Sexually transmitted
Listeriosis Listeria Routine
Lyme disease Borrelia burgdorferi Routine Not transmitted person-to-person
Lymphocytic choriomeningitis Lymphocytic choriomeningitis virus Routine Not transmitted person-to-person
Lymphogranuloma venereum Chlamydia trachomatis Routine
Malaria Plasmodium Routine Not transmitted person-to-person
Measles Measles virus Airborne 4 days after onset of rash
Measles (immunocompromised) Measles virus Airborne Duration of illness
Melioidosis Burkholderia pseudomallei Routine Not transmitted person-to-person
Meningitis Gram-negative bacterium Routine
fungus Routine
Haemophilus influenzae type b Droplet 24 hours of effective therapy
Listeria monocytogenes Routine
Neisseria meningitidis Droplet 24 hours of effective therapy
Streptococcus pneumoniae Routine
Tuberculosis Routine Rule out pulmonary disease and draining adenitis
bacterium, not otherwise specified Routine
Meningitis (aseptic) various Routine Contact for infants and young children
Molluscum contagiosum Molluscum contagiosum virus Routine
Monkeypox Monkeypox virus Airborne + Contact Airborne until smallpox ruled out; contact until lesions crusted
Mucormycosis Mucorales Routine
Multidrug-resistant organisms (MDROs) various (e.g. MRSA, VRE, ESBL) Contact Based on local guidelines
Mumps Mumps virus Droplet 5 days after onset of swelling
Necrotizing enterocolitis various Routine
Nocardiosis Nocardia Routine Not transmitted human-to-human
Orf Orf virus Routine
Parvovirus B19 (immunocompromised) Parvovirus B19 Droplet Duration of hospitalization
Parvovirus B19 (transient aplastic crisis) Parvovirus B19 Droplet 7 days
Pertussis Bordetella pertussis Droplet 5 days of effective therapy Single-patient room preferred; contacts may need post-exposure prophylaxis
Pharyngitis (infants and young children) Streptococcus pyogenes Droplet 24 hours of effective therapy
Pinworm Enterobius vermicularis Routine
Plague (bubonic) Yersinia pestis Routine
Plague (pneumonic) Yersinia pestis Droplet 48 hours of effective therapy Consider prophylaxis in healthcare workers
Pneumonia Adenovirus Droplet + Contact Duration of illness
Chlamydia pneumoniae Routine
fungus Routine
Legionella Routine Not transmitted person-to-person
Mycoplasma pneumoniae Droplet Duration of illness
Neisseria meningitidis Droplet 24 hours of effective therapy
Pneumocystis jiroveci Routine
Staphylococcus aureus Routine
Streptococcus pneumoniae Routine Droplet precautions if nosocomial outbreak
Streptococcus pyogenes Droplet 24 hours of effective therapy
bacterium, not otherwise specified Routine
Pneumonia (adults) Haemophilus influenzae type b Routine
virus, not otherwise specified Routine
Pneumonia (children) Haemophilus influenzae type b Droplet 24 hours of effective therapy
Pneumonia (infants) Chlamydia trachomatis Routine
Pneumonia (infants and children) virus, not otherwise specified Contact Duration of illness
Poliomyelitis Poliovirus Contact Duration of illness
Pressure ulcer various Routine Contact precautions if draining
Prion disease Prions Routine
Psittacosis Chlamydia psittaci Routine Not transmitted person-to-person
Q fever Coxiella burnetii Routine
Rabies Rabies virus Routine Very rare person-to-person transmission
Rat-bite fever Streptobacillus moniliformis Routine Not transmitted person-to-person
Rat-bite fever Spirillum minus Contact Not transmitted person-to-person
Relapsing fever various Routine Not transmitted person-to-person
Respiratory infection Human metapneumovirus Contact Duration of illness
Respiratory infections (adults) not otherwise specified Routine
Respiratory infection (infants and young children) Parainfluenza virus Contact Duration of illness Prolonged shedding in immunocompromised
Respiratory infection (infants and children) not otherwise specified Contact Duration of illness
Respiratory infection (infants, young children, and immunocompromised) Respiratory syncytial virus Contact Duration of illness Immunocompromised patients may have prolonged shedding
Reye syndrome Routine Not an infectious disease
Rheumatic fever Streptococcus pyogenes Routine
Rhinovirus Rhinovirus Droplet Duration of illness
Rickettsioses Rickettsia Routine Not transmitted human-to-human
Rickettsialpox (vesicular) Rickettsia akari Routine Not transmitted person-to-person
Ringworm various Routine
Rocky Mountain spotted fever Rickettsia rickettsii Routine Not transmitted person-to-person
Roseola infantum Roseolavirus Routine
Rubella Rubella virus Droplet 7 days after rash onset
Salmonellosis Salmonella Refer to Gastroenteritis
Scabies Sarcoptes scabiei Contact 24 hours of effective therapy
SARS coronavirus SARS-CoV Airborne + Droplet + Contact 10 days after symptoms resolve
Scalded skin syndrome Staphylococcus aureus Contact Duration of illness
Scarlet fever Streptococcus pyogenes Droplet 24 hours of appropriate therapy
Schistosomiasis Schistosoma Routine
Sepsis Neisseria meningitidis Droplet 24 hours of effective therapy Contacts may need post-exposure prophylaxis
Sepsis (neonatal) Group B streptococcus Routine
Shingles (disseminated or immunocompromised) Varicella-zoster virus Airborne + Contact Duration of illness
Shingles (localized in immunocompetent) Varicella-zoster virus Routine
Smallpox Smallpox virus Airborne + Contact Until all scabs have crusted and separated
Soft tissue infection (major) Staphylococcus aureus Contact Until drainage stops or is controlled
Soft tissue infection (severe) Streptococcus pyogenes Droplet + Contact 24 hours of effective therapy and drainage contained
Soft tissue infection (mild) Streptococcus pyogenes Routine If drainage controlled
Sporotrichosis Sporothrix schenckii Routine
Strongyloidiasis Strongyloides stercoralis Routine
Syphilis Treponema pallidum pallidum Routine
Syphilis (congenital) Treponema pallidum pallidum Contact 24 hours of effective therapy
Tapeworm Hymenolepis nana Routine Not transmitted person-to-person
Taenia solium Routine
not otherwise specified Routine
Tetanus Botulinum tetani Routine Not transmitted person-to-person
Tinea fungus Routine Rarely transmitted person-to-person
Toxic shock syndrome Staphylococcus aureus Routine
Streptococcus pyogenes Droplet 24 hours of effective therapy
Toxoplasmosis Toxoplasma gondii Routine Generally not transmitted person-to-person
Trachoma Chlamydia trachomatis Routine
Trench mouth various Routine
Trichinosis Trichinella spiralis Routine
Trichomoniasis Trichomonas vaginalis Routine
Tuberculosis (draining lesion) Mycobacterium tuberculosis Airborne + Contact Until clinically improving and 3 negative cultures Rule out pulmonary disease
Tuberculosis (meningitis) Mycobacterium tuberculosis Routine Rule out pulmonary disease and draining lesions
Tuberculosis (pulmonary or laryngeal) Mycobacterium tuberculosis Airborne
Tuberculosis (latent) Mycobacterium tuberculosis Routine
Tularemia (draining lesion) Mycobacterium tuberculosis Routine Not transmitted person-to-person
Tularemia (pulmonary) Mycobacterium tuberculosis Routine Not transmitted person-to-person
Typhoid fever Salmonella enterica Refer to Gastroenteritis
Typhus (epidemic/louse-borne) Rickettsia prowazekii Routine
Typhus (murine/flea-borne) Rickettsia typhi Routine Not transmitted person-to-person
Urinary tract infection including pyelonephritis various Routine
Vaccinia (vaccination site care) Vaccinia virus Routine Vaccinate healthcare workers
Vaccinia (eczema vaccinatum) Vaccinia virus Contact Until lesions are dry and crusted, and scabs separated
Vaccinia (fetal vaccinia) Vaccinia virus Contact Until lesions are dry and crusted, and scabs separated
Vaccinia (generalized vaccinia) Vaccinia virus Contact Until lesions are dry and crusted, and scabs separated
Vaccinia (progressive vaccinia) Vaccinia virus Contact Until lesions are dry and crusted, and scabs separated
Vaccinia (postvaccinia encephalitis) Vaccinia virus Routine
Vaccinia (blepharitis or conjunctivitis) Vaccinia virus Contact Until drainage stops
Vaccinia (iritis or keratitis) Vaccinia virus Routine
Vaccinia (erythema multiforme or SJS) Vaccinia virus Routine Not infectious
Varicella Varicella-zoster virus Airborne + Contact Until lesions dry and crusted
Varicella-zoster (pneumonia in immunocompromised) Varicella-zoster virus Airborne + Contact Duration of illness
Vincent angina various Routine
Viral hemorrhagic fever Crimean-Congo hemorrhagic fever virus Refer to Viral hemorrhagic fever
Ebola virus Refer to Viral hemorrhagic fever
Lassa fever virus Refer to Viral hemorrhagic fever
Marburg virus Refer to Viral hemorrhagic fever
various Droplet + Contact Duration of illness
Viral hepatitis Hepatitis B virus Routine
Hepatitis C virus Routine
Hepatitis D virus Routine
Viral hepatitis (continent) Hepatitis A virus Routine Consider vaccination as post-exposure prophylaxis
Hepatitis E virus Routine
Viral hepatitis (diapered or incontinent) Hepatitis A virus Contact <3 years: duration of hospitalization; 3-14 years: 2 weeks after onset; >14 years: 1 week after onset
Hepatitis E virus Contact Duration of illness
Viral hepatitis Hepatitis G virus Routine
Whipworm Trichuris trichiura Routine
Zygomycosis Routine Not transmitted person-to-person
various Haemophilus influenzae Refer to disease-specific recommendations
various Non-tuberculous mycobacteria Routine

Further Reading