Haemophilus ducreyi

From IDWiki
Haemophilus ducreyi / (Redirected from Chancroid)

Background

  • Causes chancroid

Microbiology

  • Fastidious Gram-negative bacillus

Epidemiology

  • Present worldwide
  • Endemic when sex workers, for example, are pressured to have sex with multiple partners despite active genital lesions

Clinical Manifestations

  • Presents initially with a papule at the site of inoculation, progressing to pustules, which rupture into painful, purulent, and shallow ulcers
    • Ulcer base often bleeds
    • In men, lesions are more common on the prepuce, coronal sulcus, or penile shaft
    • In women, lesions occur more commonly on external genitalia, but can also occur within the vagina or on the cervix
  • Often multiple ulcers
  • May have associated painful lymphadenitis, which can drain

Diagnosis

  • Not culturable
  • PCR if available
  • Most commonly diagnosed with tissue biopsy using Giemsa or Wright stains
  • Rule out other causes as appropriate with NAAT or PCR

Management