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(newest | oldest) View (newer 50 | older 50) (20 | 50 | 100 | 250 | 500)- 11:17, 14 November 2023 Aidan talk contribs created page Respiratory infection in a returned traveller (Created page with "== Etiologies == === By Incubation Period === {| class="wikitable" !Incubation Period !Infections |- |Less than 10 days |Viral: influenza, SARS, MERS, Nipah virus Bacterial: common organisms causing pneumonia (Streptococcus pneumoniae, Haemophilus influenzae), melioidosis, legionellosis, plague, pertussis, diphtheria Fungal: histoplasmosis |- |10 to 21 days |Viral: MERS, Nipah virus, hantavirus Bacterial: pe...") Tag: Visual edit
- 11:25, 1 November 2023 Aidan talk contribs created page Hand-Schüller-Christian disease (Created page with "* A form of Langerhans cell histiocytosis, also called multifocal unisystem Langerhans cell histiocytosis * Occurs in infants and children * Characterized by fever, bone lesions, and rash on scalp and ears, with a classic triad of: ** Exophathalmos ** Diabetes insipidus, from pituitary involvement ** Lytic bone lesions in the skull Category:Hematology Category:Oncology") Tag: Visual edit
- 14:22, 25 October 2023 Aidan talk contribs created page Hidradenitis suppurativa (Created page with "== Background == * Idiopathic chronic inflammatory skin condition * Also known as acne inversa or Verneuil disease === Pathophysiology === * Chronic follicular occlusive disease involving the follicular portion of the folliculopilosebaceous units === Epidemiology === * Onset between puberty and age 40 * Slight female predominance * Increased risk of metabolic syndrome * Possible association with Crohn disease (more than ulcerative colitis) * Member of th...") Tag: Visual edit
- 15:33, 23 October 2023 Aidan talk contribs created page Zyvoxam (Redirected page to Linezolid) Tags: New redirect Visual edit
- 10:26, 20 October 2023 Aidan talk contribs deleted page BALANCE (content was: "== Eligibility == === On The Wards === * Inclusion: ** Admitted but not in ICU at time the BCx result returns ** Positive culture with a pathogenic bacterium * Exclusion: ** Already enrolled in a BALANCE study ** Severely immunocompromised (ANC<0.5, SOT, HSCT) ** Prosthetic heart valve or synthetic endovascular graft ** Strong suspicion of: IE, OM, SA, undrained abscess, unremoved...", and the only contributor was "Aidan" (talk))
- 13:35, 19 October 2023 Aidan talk contribs created page Osteitis pubis (Created page with "* Chronic, non-infectious inflammatory disorder of the symphysis pubis Category:Rheumatology") Tag: Visual edit
- 15:13, 18 October 2023 Aidan talk contribs created page Dermabacter hominis (Created page with "{{DISPLAYTITLE:''Dermabacter hominis''}} == Background == * Factulative anaerobic, catalase-positive, non-motile irregular Stain::gram-positive Shape::bacillus * Member of skin flora == Clinical Manifestations == * Bacteremia, abscess, vascular graft infection, osteomyelitis, wound infection, eye infection, peritoneal dialysis infection == Management == * Routinely susceptible to vancomycin, teicoplanin, linezolid * Variab...") Tag: Visual edit
- 14:10, 18 October 2023 Aidan talk contribs created page Isolation (Redirected page to Infection control precautions by disease) Tags: New redirect Visual edit
- 07:58, 18 October 2023 Aidan talk contribs created page Category:Biologics (Created page with "Category:Medications") Tag: Visual edit
- 07:58, 18 October 2023 Aidan talk contribs created page Bispecific T-cell engager (Created page with "* Recombinant proteins that bind to two different antigens, one of which activates T cells and the other binds a cancer target * Used in treating some hematologic malignancies Category:Oncology Category:Biologics") Tag: Visual edit
- 07:56, 18 October 2023 Aidan talk contribs created page BiTE (Redirected page to Bispecific T-cell engager) Tags: New redirect Visual edit
- 12:16, 16 October 2023 Aidan talk contribs created page Pseudomonas stutzeri (Created page with "{{DISPLAYTITLE:''Pseudomonas stutzeri''}} == Clinical Manifestations == * Classically a cause of keratitis * Can cause bacteremia, urinary tract infection, skin and soft tissue infection, and otitis externa == Management == * Susceptible to similar antibiotics as Pseudomonas aeruginosa, though likely more susceptible in general Category:Gram-negative bacteria") Tag: Visual edit
- 09:42, 7 October 2023 Aidan talk contribs created page Amoebic liver abscess (Redirected page to Entamoeba histolytica) Tags: New redirect Visual edit
- 12:25, 4 October 2023 Aidan talk contribs created page Paragonimus westermani (Created page with "{{DISPLAYTITLE:''Paragonimus westermani''}} == Background == * Also known as the oriental lung fluke * Most common species of Genus::Paragonimus that infects humans === Epidemiology === * Distributed within southeast Asia and east Asia, including China, Korea, Japan, the Philippines, Taiwan, and India ** Other species are endemic to other parts of the world, including Paragonimus kellicotti in North America * Primarily transmitted by consumption of raw or und...") Tag: Visual edit
- 12:21, 4 October 2023 Aidan talk contribs created page Paragonimus (Created page with "{{DISPLAYTITLE:''Paragonimus''}} * Species of trematode * Also known as lung flukes * Multiple species can infect humans, with different geographic distributions {| class="wikitable" !Species !Geographic Distribution !Notes |- |Paragonimus westermani |China, Korea, Japan, the Philippines, Taiwan, and India |By far the most common cause of disease in humans |- |Paragonimus heterotremus |Thailand, as well as India, southern China, and Vietnam | |- |Paragonimus...") Tag: Visual edit
- 12:12, 4 October 2023 Aidan talk contribs created page Paragonimiasis (Redirected page to Paragonimus westermani) Tags: New redirect Visual edit
- 10:54, 3 October 2023 Aidan talk contribs moved page Urinary cast to Urinary microscopy
- 10:54, 3 October 2023 Aidan talk contribs created page Urinary cast (Created page with "== Interpretation == {| class="wikitable" !Syndrome !Urine Sediment !Urine Analysis |- |Prerenal AKI |bland, hyaline casts, a few fine granular casts, occasional renal tubular epithelial cells |± protein |- |ATN |renal tubular epithelial cells and casts, course granular casts, "muddy brown" casts |± protein |- |AIN |white blood cells and casts, renal tubular epithelial cells and casts, red blood cells and occasional casts |±protein, +leukocyte esterase, + bloo...") Tag: Visual edit
- 12:55, 1 October 2023 Aidan talk contribs created page Infections associated with malignancy (Created page with "== Bacteria == * Bacteremia with many bacteria is associated with new diagnosis of colorectal cancer within 1 year * Clostridium species (OR 17) and in particular Clostridium septicum (OR 17) * Gemella morbillorum (OR 15) * Fusobacterium nucleatum (OR 5 to 7) * Streptococcus bovis group (OR 9), mostly from * Streptococcus gallolyticus (OR 6) * Bacteroides species (OR 6), including Bacteroides fragilis (OR 4) and Bacteroides ovatus (O...") Tag: Visual edit
- 23:29, 30 September 2023 Aidan talk contribs created page Clostridium chauvoei (Created page with "* Gram-positive anaerobe * Causes blackleg in cattle and occasionally other small ruminants * 3 cases of infection in humans, where it can cause fatal necrotizing enterocolitis")
- 10:20, 28 September 2023 Aidan talk contribs moved page Emphysema to Pulmonary emphysema (more specific)
- 10:19, 28 September 2023 Aidan talk contribs created page Emphysema (Created page with "== Background == * A form of chronic obstructive pulmonary disease characterized by enlargement of the distal airspaces and destruction of airspace walls === Morphological Subtypes === {| class="wikitable" !Subtype !Description !Associations |- |Centrilobular emphysema |Most common, usually an upper lobe predominance |Closely associated with smoking |- |Panlobular emphysema |Involves entire acinus, more severe in lower lobes |alpha-1-antitrypsin deficiency or I...") Tag: Visual edit
- 09:36, 28 September 2023 Aidan talk contribs created page Urine drug screen (Redirected page to Urine drug testing) Tags: New redirect Visual edit
- 09:35, 28 September 2023 Aidan talk contribs created page UDS (Redirected page to Urine drug screen) Tags: New redirect Visual edit
- 14:01, 27 September 2023 Aidan talk contribs created page Neisseria elongata (Created page with "{{DISPLAYTITLE:''Neisseria elongata''}} == Background == === Microbiology === * A non-motile Stain::Gram-negative Shape::bacillus (rather than coccus) within the genus Genus::Neisseria * Catalase-Catalase::negative and superoxol-Superoxol::negative * Part of the normal oropharyngeal flora === Clinical Manifestations === * Most case reports describe endocarditis, though it is rare<ref>Youssef D, Marroush TS, Levine MT, Sharma M. Endocarditis d...") Tag: Visual edit
- 11:03, 26 September 2023 Aidan talk contribs created page IgG4-related disease (Redirected page to IgG4 disease) Tags: New redirect Visual edit
- 11:02, 26 September 2023 Aidan talk contribs created page Exophthalmos (Created page with "== Background == * Protrusion of one or both eyes anteriorly === Etiologies === * Inflammation into the orbit ** Graves disease ** Orbital cellulitis ** Mucormycosis ** Granulomatosis with polyangiitis ** IgG4-related disease * Invasion ** Benign or malignant orbital tumours, including hemangioma, neuroblastoma, neurofibromatosis, leukemia, lymphoma, paranasal sinus mucocele, pseudotomour ** Metastasis, from breast can...") Tag: Visual edit
- 11:29, 20 September 2023 Aidan talk contribs created page Acute cerebellitis (Created page with "== Background == * Inflammation of the cerebellum * Most cases are described in children === Etiologies === * Mostly idiopathic * Medications, including isoniazid (causing pyridoxine defieciency) and cytarabine * Paraneoplastic, including Castleman syndrome and Hodgkin lymphoma * Infectious ** Primary infections, including West Nile virus, Mycoplasma pneumoniae, influenza, HSV, EBV, VZV, mumps, Lyme disease, rubell...") Tag: Visual edit
- 16:14, 18 September 2023 Aidan talk contribs created page Alpha-gal syndrome (Created page with "== Background == * A meat allergy caused by exposure to certain tick bites * Caused by an IgE-mediated reaction to the carbohydrate galactose-alpha-1,3-galactose (alpha-gal) {| class="wikitable" !Region !Tick |- |Australia |Ixodes holocyclus and Ixodes australiensis |- |United States |Amblyomma americanum |- |Europe (Sweden, Germany, France, Italy, Spain) |Ixodes ricinus |- |Asia (Japan and South Korea) |Haemoaphysalis longicornis and Amblyomma te...") Tag: Visual edit
- 11:26, 17 September 2023 Aidan talk contribs created page Limbic encephalitis (Created page with "==Background== * See also paraneoplastic limbic encephalitis * Caused by inflammation (usually autoimmune) in the hippocampus and amygdala ===Etiologies=== * Paraneoplastic (most cases) ** Small cell lung cancer (most common) ** Breast cancer, testicular tumour, teratoma, Hodgkin lymphoma, thymoma ==Clinical Manifestations== * Impaired short-term memory, anterograde amnesia, behavioural and psychiatric...")
- 12:12, 14 September 2023 Aidan talk contribs created page Cholangitis (Created page with "== Definition (Tokyo 2018) == * Definite cholangitis requires all of the following: ** Signs of systemic inflammation, including fever >38°C and/or rigors, or elevation of inflammatory blood markers (WBC <4 or >10, or CRP ≥1 mg/dL) ** Signs of cholestasis, such as jaundice (total bilirubin ≥2 mg/dL), abnormal liver function (ALP, GGT, AST, or ALT >1.5x, and biliary function tests ** Biliary dilatation or evidence of etiology (stricture, stone, stent, etc.) on imagi...") Tag: Visual edit
- 09:56, 14 September 2023 Aidan talk contribs created page Good Clinical Practices (Created page with "* Regulations guiding clinical research in Canada * See also [https://www.canada.ca/en/health-canada/services/drugs-health-products/compliance-enforcement/good-clinical-practices.html Good Clinical Practices (Health Canada)] Category:Research") Tag: Visual edit
- 09:54, 14 September 2023 Aidan talk contribs created page GCP (Redirected page to Good Clinical Practices) Tags: New redirect Visual edit
- 09:39, 14 September 2023 Aidan talk contribs created page Investigator (Created page with "* In the context of clinical research in Canada, an '''investigator''' is a person responsible for the conduct of a clinical trial at a trial site ** If research at the site includes a team, the investigator is the responsible leader and may also be referred to as the principal investigator or qualified investigator * A '''principal investigator''' is US terminology, not applicable in Canada * A '''qualified investigator''' is defined by Health Canada as the person respo...") Tag: Visual edit
- 09:24, 14 September 2023 Aidan talk contribs created page Adverse event (Created page with "* Any untoward medical occurrence in a patient or research participant who is receiving a treatment * Does not necessarily have a causal relationship with the treatment Category:Research") Tag: Visual edit
- 09:22, 14 September 2023 Aidan talk contribs created page AE (Redirected page to Adverse event) Tags: New redirect Visual edit
- 09:20, 14 September 2023 Aidan talk contribs moved page Adverse antimicrobial reactions to Adverse antimicrobial reaction without leaving a redirect
- 09:19, 14 September 2023 Aidan talk contribs moved page Adverse drug reactions to Adverse drug reaction without leaving a redirect
- 09:18, 14 September 2023 Aidan talk contribs created page ADR (Redirected page to Adverse drug reaction) Tags: New redirect Visual edit
- 14:13, 30 August 2023 Aidan talk contribs created page Splenic hydatid cyst (Created page with "== Background == * Infection with Echinococcus granulosus of the liver == Differential Diagnosis == * Epidermoid cyst * Splenic pseudocyst * Splenic abscess * Splenic hematoma * Intrasplenic pancreatic pseudocyst * Cystic neoplasm of the spleen == Diagnosis == * Ultrasound and CT are best tests but appearance varies widely ** Most common appearance on ultrasound is an anechoic, smooth, round cyst ** Daughter cysts may be present ** May be able to see layers of m...") Tag: Visual edit
- 13:18, 30 August 2023 Aidan talk contribs created page Anisocoria (Created page with "== Background == * Pupils of different sizes * Usual pathophysiology includes imbalance of efferent autonomic nerves ** Parasympathetic causes miosis/constriction and sympathetic causes mydriasis/dilatation * Other cause is mechanical == Etiologies == * Greater difference in dim light ** Horner syndrome, with ipsilateral miosis, ptosis, anhidrosis, enopthalmos, and lack of ciliospinal reflex ** Cholinergic medications, such as pilocarpine to treat glaucoma...") Tag: Visual edit
- 10:11, 26 August 2023 Aidan talk contribs created page SVC syndrome (Redirected page to Superior vena cava syndrome) Tags: New redirect Visual edit
- 15:22, 24 August 2023 Aidan talk contribs added prefix "wikijc" (https://www.wikijournalclub.org/wiki/$1) (trans: 0; local: 0) to the interwiki table
- 15:18, 24 August 2023 Aidan talk contribs added prefix "microbewiki" (https://microbewiki.kenyon.edu/index.php/$1) (trans: 0; local: 0) to the interwiki table
- 15:15, 24 August 2023 Aidan talk contribs added prefix "physio-pedia" (https://www.physio-pedia.com/$1) (trans: 0; local: 0) to the interwiki table
- 09:32, 24 August 2023 Aidan talk contribs created page Clofazimine (Created page with "== Background == * Antibiotic * Indicated for leprosy and non-tuberculous mycobacteria * Has never been studied in an RCT * Mechanism of action is postulated to be redox cycling and memrane destabilization and dysfunction == Safety == === Adverse Effects === * Skin darkening: exposure-related, onset is gradual. Not permanent, will slowly resolve after stopping the drug. * Dry skin and generalized pruritus * QT prolongation and possibly torsades de pointes...") Tag: Visual edit
- 09:35, 23 August 2023 Aidan talk contribs created page Leukoerythroblastic reaction (Created page with "== Background == * A finding on peripheral blood film that is characterized by the presence of immature erythroid cells and myeloid precursors (metamyelocytes, myelocytes, promyelocytes, myeloblasts, and blasts) as well as, exclusively in myelofibrotic disorders, teardrop cells in the peripheral blood == Etiologies == * Malignancy (60%) ** Solid organ (40%) ** Hematologic (20%) * Benign (40%) ** Hemolysis ** Myeloproliferative disease ** Infection ** Hemor...") Tag: Visual edit
- 13:52, 16 August 2023 Aidan talk contribs created page Neutropenia (Created page with "== Etiologies == === Congenital === * Constitutional neutropenia: mild (ANC>1000), chronic * Benign ethnic neutropenia: mild (ANC>1000), chronic, usually in patients with Mediterranean or African ancestry * Benign familial neutropenia: same as above, but hereditary and not associated with a specific ethnicity * Cyclic neutropenia: hereditary, with severe neutropenia on a 21-day cycle since childhood * Others: severe congenital neutropenia, Schwachman-Diamond sy...") Tag: Visual edit
- 10:05, 16 August 2023 Aidan talk contribs created page Drug-induced neutropenia (Created page with "{| class="wikitable sortable" !Class !Drug !Frequency reported !Nature of reaction |- | rowspan="7" |Antibiotics |Semisynthetic penicillins (amoxicillin, ampicillin) |Moderate |Both |- |Cephalosporins |Moderate |Both |- |Vancomycin |High |Both |- |Macrolides |Low |Neutropenia |- |TMP-SMX |High |Agranulocytosis |- |Dapsone |High |Agranulocytosis |- |Chloramphenicol |High |Agranulocytosis |- | rowspan="2" |Antifungals |Amphotericin |Low |Neutropenia |- |Flucytosine |...") Tag: Visual edit
- 09:59, 16 August 2023 Aidan talk contribs created page Cyclic neutropenia (Created page with "== Background == * Rare congenital disease * Autosomal dominant from mutations in ''ELANE'' gene == Clinical Manifestations == * Cycles of severe neutropenia approximately every 21 days (range 2 to 5 weeks) * Duration of neutropenia varies by patient but is consistent for each patient * Usually mild syndrome, though some can develop aphthous ulcers during the nadir Category:Hematology") Tag: Visual edit