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17:51, 9 September 2025 Aidan talk contribs created page Avacopan (Created page with "* Complement 5a receptor antagonist * Indicated for granulomatosis with polyangiitis and microscopic polyangiitis Category:Rheumatology Category:Medications")
15:03, 9 September 2025 Aidan talk contribs created page CR:DOI:cec85d75d06e8681143a9c823fe4b66f (Created page with "{{#scite: |reference=milosavljevic2021an |type=journal-article |title=Antimicrobial treatment of Corynebacterium striatum invasive infections: a systematic review |author=Milos N. Milosavljevic;Jovana Z. Milosavljevic;Aleksandar G. Kocovic;Srdjan M. Stefanovic;Slobodan M. Jankovic;Miralem Djesevic;Milica N. Milentijevic|+sep=; |journal=Revista do Instituto de Medicina Tropical de São Paulo |publisher=FapUNIFESP (SciELO) |year=2021 |volume=63 |doi=10.1590/s1678-...")
18:13, 8 September 2025 Aidan talk contribs created page Eosinophilic cellulitis (Created page with "== Background == * Idiopathic syndrome of eosinophilic infiltration into skin * Many proposed triggers but none definite == Clinical Manifestations == * Sudden onset large, inflamed edematous patches, often with vesicles or bullae mimicking cellulitis * Often preceded by pruritus or burning * Often on trunk and extremities * Fevers may be absent or low-grade * Patches evolve over days, and can have central healing while border becomes purple * Patches regress with...") Tag: Visual edit
00:53, 4 September 2025 Aidan talk contribs created page Streptococcus gordonii (Created page with "== Background == {{DISPLAYTITLE:''Streptococcus gordonii''}} * Species of Stain::Gram-positive Shape::coccus within the genus Genus::Streptococcus * Commensal member of skin, oral, and intestinal flora == Clinical Manifestations == * Apical periodontitis * Infective endocarditis (about 40-50% of patients with bacteremia will have endocarditis) * Also: empyema, vertebral osteomyelitis/discitis, liver abscess Category:Gram-positive cocci") Tag: Visual edit
19:20, 21 August 2025 Aidan talk contribs created page Parkinson-plus syndrome (Created page with "* Group of neurodegenerative diseases similar to Parkinson disease {| class="wikitable" ! !Lewy-body disease !Multiple system atrophy !Corticobasal degeneration !Progressive supranuclear palsy |- |Epidemiology |Common; 30% of all dementia cases |2 to 5 cases per 100,000, mean onset 54 years |5 to 7 per 100,000, mean onset early 60s |3 to 7 per 100,000 |- |Clinical manifestations |Deficits in attention, cognition, visuospatial function, with visual ha...") Tag: Visual edit
14:51, 20 August 2025 Aidan talk contribs created page CR:DOI:1c9d23338034a184da12d3bfc6764267 (Created page with "{{#scite: |reference=wong2015ca |type=journal-article |title=Canadian Public Health Laboratory Network laboratory Guidelines for the Diagnosis of Neurosyphilis in Canada |author=Tom Wong;Kevin Fonseca;Max A Chernesky;Richard Garceau;Paul N Levett;Bouchra Serhir|+sep=; |journal=Canadian Journal of Infectious Diseases and Medical Microbiology |publisher=Wiley |year=2015 |volume=26 |issue=A |doi=10.1155/2015/167484 |issn=1712-9532;1918-1493|+sep=; |retrieved-fro...")
15:48, 19 August 2025 Aidan talk contribs created page Dificid (Redirected page to Fidaxomicin) Tags: New redirect Visual edit
15:48, 19 August 2025 Aidan talk contribs created page Fidaxomicin (Created page with "* Antibiotics indicated for Clostridioides difficile infection * Standard dose is 200 mg p.o. twice daily for 10 days * Pulse-tapered regimen is 200 mg once daily for 7 days followed by 200 mg fidaxomicin every other day for the remaining 13 dosesCiteRef::skinner2021a * In Ontario, EAP criteria for approval through the telephone request service includes: third or subsequent episode treated with vancomycin within 6 months; treatment failure despite at least 7 days...") Tag: Visual edit
15:46, 18 August 2025 Aidan talk contribs created page Polatuzumab vedotin (Created page with "* Anti-CD79b antibody with a humanized IgG1 monoclonal antibody and monomethyl auristatin E (MMAE, an antimitotic agent) * Indicated for diffuse large B-cell lymphoma * Adverse effects ** Include rash, anorexia, diarrhea, nausea/vomiting, fatigue, myelosuppression and opportunistic infections ** Infusion reactions can occur as late as 24 hours post-infusion ** Tumour lysis syndrome ** Hepatotoxicity, mostly low-grade and reversible ** Serious infections, includin...") Tag: Visual edit
14:25, 1 August 2025 Aidan talk contribs created page Vibrio metschnikovii (Created page with "{{DISPLAYTITLE:''Vibrio metschnikovii''}} == Background == * Stain::Gram-negative Shape::bacillus within the genus Genus::Vibrio * Halophilic * Found in aquatic habitats, including streams, lakes, marine waters, and sewage, and in shellfish == Clinical Manifestations == * Rare cause of severe infections, including pneumonia, cellulitis, and bacteremia Category:Gram-negative bacilli") Tag: Visual edit
16:28, 30 July 2025 Aidan talk contribs created page Cefixime (Created page with "== Background == * Third-generation cephalosporin == Dosing == * Usual dose: 400 mg p.o. once daily * Enteric fever: 200 mg p.o. twice daily for 10 to 14 days === Renal Dosing === {| class="wikitable" !CrCl !Dose |- |≥60 |400 mg p.o. daily |- |>20 to <60 |300 mg p.o. daily |- |≤20 |200 mg p.o. daily |- |IHD |300 mg p.o. daily |- |PD |200 mg p.o. daily |} Category:Cephalosporins") Tag: Visual edit
15:53, 29 July 2025 Aidan talk contribs created page CR:DOI:6488adb7ce6690a2b5ec71fdb784203d (Created page with "{{#scite: |reference=tewoldemedhin2024pe |type=journal-article |title=Persistent Fever in Tuberculosis: Clinical Experience and Literature Review |author=Bereket Tewoldemedhin;Saif Al-Ethawi;Wassim Abouzeid;Charity Iheagwara;Maria Szabela;Jack Boghossian;Jihad Slim|+sep=; |journal=Cureus |publisher=Springer Science and Business Media LLC |year=2024 |doi=10.7759/cureus.69391 |issn=2168-8184 |retrieved-from=https://dx.doi.org/ |retrieved-on=2025-07-29 |@show=tr...")
14:36, 29 July 2025 Aidan talk contribs created page Tryptase (Created page with "* Serum tryptase is a laboratory test used to investigate suspected anaphylaxis * Acute elevation suggests mast cell degranulation, either IgE-mediated or directly * Rises within minutes of onset of anaphylaxis, and reverts to normal within 6 to 24 hours ** Height of increase often correlates to severity of anaphylaxis * NICE guidelines in the UK recommend taking a sample as soon as possible, with a second sample within 1 to 2 hours of onset of symptoms (no later than 4...") Tag: Visual edit
13:31, 29 July 2025 Aidan talk contribs created page Venous stasis (Created page with "== Management == * Compression ** Rule out arterial disease (compression is contraindicated by ABI less than 0.6) ** 30 to 40 mm Hg compression, as tolerated * Elevation above heart when at rest * Exercise * Wound care Category:Vascular surgery") Tag: Visual edit
18:23, 24 July 2025 Aidan talk contribs created page NPH (Redirected page to Normal pressure hydrocephalus) Tags: New redirect Visual edit
13:56, 24 July 2025 Aidan talk contribs created page Brukinsa (Redirected page to Zanubrutinib) Tags: New redirect Visual edit
13:55, 24 July 2025 Aidan talk contribs created page Zanubrutinib (Created page with "* Bruton's tyrosine kinase inhibitor, inhibiting proliferation of malignant B cells * Half-life 2 to 4 hours * Adverse effects ** Atrial fibrillation, hypertension ** Rash ** Constipation, diarrhea, nausea, vomiting ** Fatigue, dizziness, headache ** Hemorrhage ** Myelosuppression ** Infections, including severe infections *** Pneumonia most common *** Hepatitis B virus and VZV reactivation ** Tumour lysis syndrome (in CLL) ** MSK pain ** Secondary ma...") Tag: Visual edit
17:52, 23 July 2025 Aidan talk contribs created page Multicentric Castleman disease (Created page with "== Background == * Rare lymphoproliferative disorder * Associated with HHV-8, but not necessarily specific to HIV == Clinical Manifestations == * Fevers and chills * Generalized lymphadenopathy * Can progress to large B cell lymphoma Category:Hematology") Tag: Visual edit
17:45, 23 July 2025 Aidan talk contribs created page Cherry hemangioma (Created page with "== Background == * Age-related spots on the skin == Etiologies == * Most often age-related * Pregnancy * Certain genetic mutations * Eruptive cherry angiomas (many at once) ** Topical nitrogen mustard (treatment for vitiligo) ** Cyclosporine ** Chronic graft-versus-host disease ** Lymphoproliferative diseases ** Multicentric Casselman disease ** Ramucirumab ** HHV-8 infection == Clinical Manifestations == * Characterized as dome-shaped, bright, r...") Tag: Visual edit
17:42, 23 July 2025 Aidan talk contribs created page Cherry angioma (Redirected page to Cherry hemangioma) Tags: New redirect Visual edit
16:12, 23 July 2025 Aidan talk contribs created page Vfend (Redirected page to Voriconazole) Tags: New redirect Visual edit
18:19, 22 July 2025 Aidan talk contribs created page Pseudescherichia vulneris (Created page with "{{DISPLAYTITLE:''Pseudescherichia vulneris''}} == Background == * Stain::Gram-negative Shape::bacillus within the genus Genus::Pseudescherichia * Oxidase-Oxidase::negative, urease-Urease::negative, indole-negative * Previously known as ''Escherichia vulneris'' * Rare cause of infections in humans == Management == * Similar to other Enterobacterales such as Escherichia coli Category:Gram-negative bacilli") Tag: Visual edit
17:45, 21 July 2025 Aidan talk contribs created page CR:DOI:b695055582a8f9cc12bb5f979008ce8c (Created page with "{{#scite: |reference=marín2017id |type=journal-article |title=Identification of Emerging Human Mastitis Pathogens by MALDI-TOF and Assessment of Their Antibiotic Resistance Patterns |author=María Marín;Rebeca Arroyo;Irene Espinosa-Martos;Leónides Fernández;Juan M. Rodríguez|+sep=; |journal=Frontiers in Microbiology |publisher=Frontiers Media SA |year=2017 |volume=8 |doi=10.3389/fmicb.2017.01258 |issn=1664-302X |retrieved-from=https://dx.doi.org/ |retrie...")
17:45, 21 July 2025 Aidan talk contribs created page Mastitis (Created page with "== Background == * Acute inflammation of the breast tissue * Main causes appear to be either milk stasis (causing non-infectious inflammation) and infection === Microbiology === * Often non-infectious * Staphylococus species are most common ** Staphylococcus aureus ** Coagulase-negative staphylococci, particularly Staphylococcus epidermidis * Streptococcus species, including Streptococcus mitis, Streptococcus salivarius, and Streptococcus parasan...") Tag: Visual edit
23:33, 20 July 2025 Aidan talk contribs created page Toxocara (Created page with "{{DISPLAYTITLE:''Toxocara''}} == Background == * Genus of nematode * Includes two species of medical importance: ** Toxocara canis, the dog roundworm ** Toxocara cati, the cat roundworm * Dogs/cats are the definitive hosts, while humans are incidental hosts ** In humans, the larva are unable to mature into adult worms or to release eggs * Distributed worldwide, particularly in low-resource settings with high numbers of feral dog or cat populations...") Tag: Visual edit
23:22, 20 July 2025 Aidan talk contribs created page Loeffler endocarditis (Created page with "== Background == * Restrictive cardiomyopathy caused by hypereosinophilic syndrome (including idiopathic) * Also known as eosinophilic endomyocardial disease and fibroblastic endocarditis == Clinical Manifestations == * Typically presents with heart failure (dyspnea, fatigue, orthopnea, paroxysmal nocturnal dyspnea) * Persistent hypereosinophilia (greater than 1.5 on 2 measurements) Category:Cardiology") Tag: Visual edit
23:05, 20 July 2025 Aidan talk contribs created page Toxocariasis (Redirected page to Toxocara) Tags: New redirect Visual edit
18:09, 17 July 2025 Aidan talk contribs created page Ehlers-Danlos syndrome (Created page with "* May be associated with CVID Category:Rheumatology") Tag: Visual edit
16:43, 16 July 2025 Aidan talk contribs created page Granulomatous inflammation (Created page with "== Background == * A histological finding on biopsy with a wide differential === Etiologies By Histologic Pattern === {| class="wikitable" !Pattern !Etiologies |- |Foreign body |talc, starch, sutures, injectable fillers including hyaluronic acid |- |Necrotizing granuloma |Infectious: TB, NTM, coccidiomycosis, cryptococcosis, histoplasmosis, blastomycosis, aspergillosis, mucor, brucellosis, nocardiosis, yersiniosis, cat-scra...") Tag: Visual edit
23:45, 7 July 2025 Aidan talk contribs created page Quinine toxicity (Created page with "== Background == * Quinine was originally an extract from the cinchona tree * Historically used to treat fevers and diarrhea, and eventually malaria * May be consumed recreationally in the form of tonic water === Pathophysiology === * It acts as a class qA antiarrhythmic, blocking both sodium and potassium, leading to long QRS and QT intervals * Toxic to the retina == Clinical Manifestations == * '''Cinchonism''': nausea, vomiting, and tinnitus ** Sweating, nausea,...") Tag: Visual edit
23:39, 7 July 2025 Aidan talk contribs created page Conchonism (Redirected page to Quinine toxicity) Tags: New redirect Visual edit
18:51, 4 July 2025 Aidan talk contribs created page Idiopathic inflammatory myopathy (Created page with "== Background == * A group of disorders that includes: ** Dermatomyositis ** Antisynthetase syndrome ** Immune-mediated necrotizing myopathy (IMNM) ** Inclusion body myositis (IBM) ** Myositis secondary to other rheumatologic diseases == Clinical Manifestations == * Typically characterized by muscle weakness rather than pain Category:Rheumatology") Tag: Visual edit
14:26, 4 July 2025 Aidan talk contribs created page Anifrolumab (Created page with "* Monoclonal antibody targeting type I interferon (IFN-I) receptor (IFNAR1) * Indicated for systemic lupus erythematosus * Adverse effects include: ** Upper respiratory tract infection ** Nasopharyngitis ** Infusion-related reaction ** Bronchitis ** Urinary tract infection ** Sinusitis ** Increased risk of herpes zoster Category:Monoclonal antibodies Category:Rheumatology") Tag: Visual edit
14:23, 4 July 2025 Aidan talk contribs created page Saphnelo (Redirected page to Anifrolumab) Tags: New redirect Visual edit
20:39, 3 July 2025 Aidan talk contribs created page CR:DOI:9611e78c50257cc66986034136ab0484 (Created page with "{{#scite: |reference=bokaie2020se |type=journal-article |title=Seroprevalence of toxoplasma gondii infection: An umbrella review of updated systematic reviews and meta-analyses |author=Saied Bokaie;Vahid Rahmanian;Karamatollah Rahmanian;AbdolrezaSotoodeh Jahromi|+sep=; |journal=Journal of Family Medicine and Primary Care |publisher=Medknow |year=2020 |volume=9 |issue=8 |pages=3848 |doi=10.4103/jfmpc.jfmpc_753_20 |issn=2249-4863 |retrieved-from=https://dx.doi...")
15:02, 3 July 2025 Aidan talk contribs created page CR:DOI:ab27f1cd0da3983b47173ebcc281e3d5 (Created page with "{{#scite: |reference=garg2025ev |type=journal-article |title=Evaluating the causes associated with false positive Galactomannan assay in suspected cases of respiratory fungal infections |author=Parul Garg;Shipra Suyal;Desh Deepak;Sneha Hembrom;Ankit K. Chauhan;Nirmalajit Kaur;Shalini Malhotra|+sep=; |journal=Journal of Family Medicine and Primary Care |publisher=Ovid Technologies (Wolters Kluwer Health) |year=2025 |volume=14 |issue=2 |pages=736-742 |doi=10.410...")
15:01, 3 July 2025 Aidan talk contribs created page CR:DOI:a632d19cdf891eb1c2501a3d3256819c (Created page with "{{#scite: |reference=ko2016mu |type=journal-article |title=Multiple myeloma as a major cause of false-positive galactomannan tests in adult patients with cancer |author=Jae-Hoon Ko;Kyong Ran Peck;Ji Yong Lee;Sun Young Cho;Young Eun Ha;Cheol-In Kang;Doo Ryeon Chung;Kihyun Kim;Eun-Suk Kang;Jae-Hoon Song|+sep=; |journal=Journal of Infection |publisher=Elsevier BV |year=2016 |volume=72 |issue=2 |pages=233-239 |doi=10.1016/j.jinf.2015.10.014 |issn=0163-4453 |retr...")
15:00, 3 July 2025 Aidan talk contribs created page CR:DOI:ebbd1eb2f8fe9a223da5222d34020535 (Created page with "{{#scite: |reference=warnock2014re |type=journal-article |title=Reduction in False-Positive Aspergillus Serum Galactomannan Enzyme Immunoassay Results Associated with Use of Piperacillin-Tazobactam in the United States |author=Paschalis Vergidis;Raymund R. Razonable;L. Joseph Wheat;Lynn Estes;Angela M. Caliendo;Lindsey R. Baden;John R. Wingard;John Baddley;Maha Assi;Steven Norris;Pranatharthi Chandrasekar;Ryan Shields;Hong Nguyen;Alison Freifeld;Richard Kohler;Martin...")
14:59, 3 July 2025 Aidan talk contribs created page CR:DOI:6c48ddc8484652e83a2a1dfbefec41f2 (Created page with "{{#scite: |reference=hung2021in |type=journal-article |title=Investigating Factors of False-Positive Results of Aspergillus Galactomannan Assay: A Case–Control Study in Intensive Care Units |author=Yu-Hsuan Hung;Hui-Hsiung Lai;Hui-Chuan Lin;Kuo-Shao Sun;Chung-Yu Chen|+sep=; |journal=Frontiers in Pharmacology |publisher=Frontiers Media SA |year=2021 |volume=12 |doi=10.3389/fphar.2021.747280 |issn=1663-9812 |retrieved-from=https://dx.doi.org/ |retrieved-on=20...")
14:57, 3 July 2025 Aidan talk contribs created page CR:DOI:77e3275d368b440288fd6cded779a8e7 (Created page with "{{#scite: |reference=demiraslan2016as |type=journal-article |title=Assessing the risk of false positive serum galactomannan among patients receiving piperacillin/tazobactam for febrile neutropenia |author=Hayati Demiraslan;M. Altay Atalay;Esma Eren;Koray Demir;Leylagul Kaynar;A. Nedret Koc;Mehmet Doganay|+sep=; |journal=Medical Mycology |publisher=Oxford University Press (OUP) |year=2016 |pages=myw129 |doi=10.1093/mmy/myw129 |issn=1369-3786;1460-2709|+sep=; |r...")
14:55, 3 July 2025 Aidan talk contribs created page CR:DOI:181cb1b3913fe2b0bebadb2b49ec94de (Created page with "{{#scite: |reference=shin2024fa |type=journal-article |title=False-positive results of galactomannan assays in patients administered glucose-containing solutions |author=Dong Woo Shin;Jungwon Cho;Kyung Suk Choi;Jungwha Lee;Yunsang Choi;Seong Jin Choi;Sang-A Kim;Song Mi Moon;Eu Suk Kim;Hong Bin Kim;Kyoung Un Park;Yun Ji Hong;Kyoung-Ho Song|+sep=; |journal=Scientific Reports |publisher=Springer Science and Business Media LLC |year=2024 |volume=14 |issue=1 |doi=10...")
14:45, 3 July 2025 Aidan talk contribs created page CR:DOI:519f0a4493c83042edb25269a53962fc (Created page with "{{#scite: |reference=benoliel2012tr |type=journal-article |title=Trigeminal autonomic cephalgias |author=Rafael Benoliel |journal=British Journal of Pain |publisher=SAGE Publications |year=2012 |volume=6 |issue=3 |pages=106-123 |doi=10.1177/2049463712456355 |issn=2049-4637;2049-4645|+sep=; |retrieved-from=https://dx.doi.org/ |retrieved-on=2025-07-03 |@show=true }}")
18:18, 30 June 2025 Aidan talk contribs created page CR:DOI:17a62a592b7a4b041fbcd385b1b911e4 (Created page with "{{#scite: |reference=haddad2023bl |type=journal-article |title=Bloodstream Infection Due to Coagulase-Negative Staphylococci: Impact of Species on Prevalence of Infective Endocarditis |author=Sara F. Haddad;Brian D. Lahr;Sebastian Santos Patarroyo;Supavit Chesdachai;Kami D. Kies;John C. O’Horo;Daniel C. DeSimone;Parham Sendi;Larry M. Baddour|+sep=; |journal=Antibiotics |publisher=MDPI AG |year=2023 |volume=12 |issue=9 |pages=1453 |doi=10.3390/antibiotics1209...")
18:16, 30 June 2025 Aidan talk contribs created page CR:DOI:35060827d516f36a47d3d1d5e441235d (Created page with "{{#scite: |reference=ramos-martínez2023ri |type=journal-article |title=Risk of endocarditis among patients with coagulase-negative Staphylococcus bacteremia |author=Antonio Ramos-Martínez;Patricia González-Merino;Elena Suanzes-Martín;Marta Murga-de la Fuente;Gabriela Escudero-López;Ane Andrés-Eisenhofer;Esther Expósito-Palomo;Andrea Gutierrez-Villanueva;Itziar Diego-Yagüe;Elena Múñez;Ana Fernandez-Cruz;Jorge Calderón-Parra|+sep=; |journal=Scientific Repor...")
14:40, 30 June 2025 Aidan talk contribs created page Bendamustine (Created page with "== Background == * Alkylating agent containing a purine-like benzimidazole ring * Indicated for CLL and non-Hodgkin lymphoma == Safety == * Common: nausea, vomiting, fatigue, myelosuppression, diarrhea, fevers, chills, constipation, anorexia, weight loss, headache, and mucositis * Myelosuppression, which may be fatal * Infections, including CMV and VZV, reactivation of hepatitis B * Infusion reactions are common * Tumour lysis syndrome, par...") Tag: Visual edit
18:52, 27 June 2025 Aidan talk contribs created page Quinacrine (Created page with "== Dosing == * Giardia duodenalis (last-line treatment): 6 mg/kg per day orally divided in three doses (maximum dose 100 mg per dose) for five days == Safety == * Adverse effects including nausea, vomiting, dizziness, headaches, psychosis, yellow-orange discoloration of skin and mucosa, hemolysis (in G6PD deficiency) Category:Antiparasitics") Tag: Visual edit
18:01, 27 June 2025 Aidan talk contribs created page CR:DOI:4c8ed7266ebe522f12225665825998fa (Created page with "{{#scite: |reference=van den bijllaardt2014ra |type=journal-article |title=Rapid clearance of Giardia lamblia DNA from the gut after successful treatment |author=W. van den Bijllaardt;I.T. Overdevest;A.G. Buiting;J.J. Verweij|+sep=; |journal=Clinical Microbiology and Infection |publisher=Elsevier BV |year=2014 |volume=20 |issue=11 |pages=O972-O974 |doi=10.1111/1469-0691.12626 |issn=1198-743X |retrieved-from=https://dx.doi.org/ |retrieved-on=2025-06-27 |@sh...")
16:06, 27 June 2025 Aidan talk contribs created page Vabomere (Redirected page to Meropenem-vaborbactam) Tags: New redirect Visual edit
15:58, 27 June 2025 Aidan talk contribs created page Tinidazole (Created page with "== Background == * Antiparasitic and antibiotic * Known as Fasigyn (Pfizer), with 500 mg and 1000 mg tablets == Dosing == * Giardiasis: 2 g p.o. once * Only available in Canada through the Special Access Program Category:Antimicrobials") Tag: Visual edit
15:56, 27 June 2025 Aidan talk contribs created page Fasigyn (Redirected page to Tinidazole) Tags: New redirect Visual edit