Thrombocytopenia: Difference between revisions

Latest revision as of 13:01, 25 March 2024

Rule out secondary causes with hepatitis C virus, HIV, and Helicobacter pylori serology

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 ==Differential Diagnosis==
+*Pseudothrombocytopenia
 *Decreased production
 **Viral infection
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 *Destruction/Consumption
 **[[Immune-mediated thrombocytopenic purpura]] (ITP)
+***Primary ITP
-***[[Hepatitis C]], [[HIV]], and [[Helicobacter pylori]]
+***[[Hepatitis C]], [[HIV]], and [[Helicobacter pylori]]; also [[CMV]], [[EBV]], [[VZV]], [[Zika virus]]
-***Medications
-****More likely: [[abciximab]], beta-lactams (including [[penicillins]] and [[cephalosporins]]), [[carbamazepine]], [[epifitabide]], gold compounds, [[Heparin-inducted thrombocytopenia|heparin]], [[linezolid]], MMR vaccine, [[phenytoin]], [[piperacillin]], [[quinidine]], [[quinine]], [[rifampin]], sulfonamides (including [[TMP-SMX]]), [[valproic acid]], and [[vancomycin]]
+***Medications: [[abciximab]], beta-lactams (including [[penicillins]] and [[cephalosporins]]), [[carbamazepine]], [[epifitabide]], gold compounds, [[Heparin-inducted thrombocytopenia|heparin]], [[linezolid]], [[MMR vaccine]], [[phenytoin]], [[piperacillin]], [[quinidine]], [[quinine]], [[rifampin]], sulfonamides (including [[TMP-SMX]]), [[valproic acid]], and [[vancomycin]]
+***Autoimmune: [[antiphospholipid syndrome]], [[Evans syndrome]], [[IBD]], [[RA]], [[SLE]]
+***[[CVID]]
+***[[CLL]]
+***[[Lymphoma]]
 **[[Thrombotic microangiopathy]]
 ***[[TTP]]/[[HUS]], other TMAs