Drug-drug interactions: Difference between revisions
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|CYP1A2 |
|CYP1A2 |
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|[[amiodarone]]<br />[[cimetidine]]<br />'''[[ciprofloxacin]]''' |
|[[amiodarone]]<br />[[cimetidine]]<br />'''[[ciprofloxacin]]''' |
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|[[fluvoxamine]]<br />'''[[interferon]]'''<br />methoxsalen |
|[[fluvoxamine]]<br />'''[[interferon]]'''<br />[[methoxsalen]] |
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|[[Nicotine use disorder|cigarette smoking]]<br />[[Cannabis use disorder|marijuana smoking]]<br />[[modafinil]]<br />'''[[nafcillin]]''' |
|[[Nicotine use disorder|cigarette smoking]]<br />[[Cannabis use disorder|marijuana smoking]]<br />[[modafinil]]<br />'''[[nafcillin]]''' |
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|[[amitriptyline]]<br />[[caffeine]]<br />[[clomipramine]]<br />[[clozapine]]<br />[[cyclobenzaprine]]<br />[[estradiol]]<br />[[fluvoxamine]]<br />[[haloperidol]] |
|[[amitriptyline]]<br />[[caffeine]]<br />[[clomipramine]]<br />[[clozapine]]<br />[[cyclobenzaprine]]<br />[[estradiol]]<br />[[fluvoxamine]]<br />[[haloperidol]] |
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|mexiletine<br />[[naproxen]]<br />[[olanzapine]]<br />[[ondansetron]]<br />phenacetine<br />[[propranolol]]<br />riluzole<br />ropivacaine |
|[[mexiletine]]<br />[[naproxen]]<br />[[olanzapine]]<br />[[ondansetron]]<br />[[phenacetine]]<br />[[propranolol]]<br />[[riluzole]]<br />[[ropivacaine]] |
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|tacrine<br />[[theophylline]]<br />[[tizanidine]]<br />[[verapamil]]<br /> |
|[[tacrine]]<br />[[theophylline]]<br />[[tizanidine]]<br />[[verapamil]]<br />[[Warfarin|R-warfarin]]<br />[[zileuton]]<br />[[zolmitriptan]] |
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!CYP |
!CYP |
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|CYP2B6 |
|CYP2B6 |
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|ticlopidine |
|[[ticlopidine]] |
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|thiotepa |
|[[thiotepa]] |
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|[[phenobarbital]]<br />'''[[rifampin]]''' |
|[[phenobarbital]]<br />'''[[rifampin]]''' |
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|[[bupropion]]<br />[[cyclophosphamide]] |
|[[bupropion]]<br />[[cyclophosphamide]] |
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|CYP2C8 |
|CYP2C8 |
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|[[gemfibrozil]]<br />[[montelukast]]<br />[[pioglitazone]] |
|[[gemfibrozil]]<br />[[montelukast]]<br />[[pioglitazone]] |
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|quercetin<br />[[rosiglitazone]]<br />'''[[trimethoprim]]''' |
|[[quercetin]]<br />[[rosiglitazone]]<br />'''[[trimethoprim]]''' |
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|'''[[rifampin]]''' |
|'''[[rifampin]]''' |
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|amodiaquine<br />'''[[dasabuvir]]''' |
|[[amodiaquine]]<br />'''[[dasabuvir]]''' |
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|cerivastatin<br />[[paclitaxel]] |
|[[cerivastatin]]<br />[[paclitaxel]] |
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|torsemide<br />[[repaglinide]] |
|[[torsemide]]<br />[[repaglinide]] |
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|- |
|- |
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!CYP |
!CYP |
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|CYP2C9 |
|CYP2C9 |
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|[[amiodarone]]<br />[[fenofibrate]]<br />'''[[fluconazole]]'''<br />[[fluvastatin]]<br />[[fluvoxamine]]<br />'''[[isoniazid]]''' |
|[[amiodarone]]<br />[[fenofibrate]]<br />'''[[fluconazole]]'''<br />[[fluvastatin]]<br />[[fluvoxamine]]<br />'''[[isoniazid]]''' |
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|[[probenecid]]<br />[[sertraline]]<br />'''[[sulfamethoxazole]]'''<br />teniposide<br />'''[[voriconazole]]'''<br />zafirlukast |
|[[probenecid]]<br />[[sertraline]]<br />'''[[sulfamethoxazole]]'''<br />[[teniposide]]<br />'''[[voriconazole]]'''<br />[[zafirlukast]] |
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|'''[[rifampin]]'''<br />secorbarbital |
|'''[[rifampin]]'''<br />[[secorbarbital]] |
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|[[amitriptyline]]<br />[[celecoxib]]<br />[[diclofenac]]<br />[[fluoxetine]]<br />[[fluvastatin]]<br />[[glipizide]]<br />[[glyburide]]<br />[[ibuprofen |
|[[amitriptyline]]<br />[[celecoxib]]<br />[[diclofenac]]<br />[[fluoxetine]]<br />[[fluvastatin]]<br />[[glipizide]]<br />[[glyburide]]<br />[[ibuprofen]] |
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|[[irbesartan]]<br />[[lornoxicam]]<br />[[losartan]]<br />[[meloxicam]]<br />[[nateglinide]]<br />[[omeprazole]]<br />[[phenytoin]] |
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|[[piroxicam]]<br />[[rosiglitazone]]<br />[[rosuvastatin]]<br />[[Warfarin|S-warfarin]]<br />[[tamoxifen]]<br />[[tolbutamide]]<br />[[torsemide]] |
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!CYP |
!CYP |
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|- |
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|CYP2C19 |
|CYP2C19 |
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|[[cimetidine]]<br />[[esomeprazole]]<br />felbamate<br />[[fluoxetine]]<br />fluvoxamine<br />[[indomethacin]]<br />'''[[ketoconazole]]'''<br />[[lansoprazole]] |
|[[cimetidine]]<br />[[esomeprazole]]<br />[[felbamate]]<br />[[fluoxetine]]<br />[[fluvoxamine]]<br />[[indomethacin]]<br />'''[[ketoconazole]]'''<br />[[lansoprazole]] |
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|[[modafinil]]<br />[[omeprazole]]<br />oxcarbazepine<br />[[pantoprazole]]<br />[[probenecid]]<br />[[rabeprazole]]<br />ticlopidine<br />[[topiramate]] |
|[[modafinil]]<br />[[omeprazole]]<br />[[oxcarbazepine]]<br />[[pantoprazole]]<br />[[probenecid]]<br />[[rabeprazole]]<br />[[ticlopidine]]<br />[[topiramate]] |
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|[[carbamazepine]]<br />norethindrone<br />prednisone<br />'''[[rifampin]]''' |
|[[carbamazepine]]<br />[[norethindrone]]<br />[[prednisone]]<br />'''[[rifampin]]''' |
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|carisoprodol<br />'''[[chloramphenicol]]'''<br />[[citalopram]]<br />clomipramine<br />cyclophosphamide<br />esomeprazole<br />hexobarbital<br />indomethacin |
|[[carisoprodol]]<br />'''[[chloramphenicol]]'''<br />[[citalopram]]<br />[[clomipramine]]<br />[[cyclophosphamide]]<br />[[esomeprazole]]<br />[[hexobarbital]]<br />[[indomethacin]] |
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|[[lansoprazole]]<br />moclobemide<br />'''[[nelfinavir]]'''<br />nilutamide<br />[[omeprazole]]<br />[[pantoprazole]]<br />[[phenobarbital]]<br />[[phenytoin]] |
|[[lansoprazole]]<br />[[moclobemide]]<br />'''[[nelfinavir]]'''<br />[[nilutamide]]<br />[[omeprazole]]<br />[[pantoprazole]]<br />[[phenobarbital]]<br />[[phenytoin]] |
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|primidone<br />[[progesterone]]<br />'''[[proguanil]]'''<br />[[propranolol]]<br />[[rabeprazole]]<br />teniposide<br />'''[[voriconazole]]''' |
|[[primidone]]<br />[[progesterone]]<br />'''[[proguanil]]'''<br />[[propranolol]]<br />[[rabeprazole]]<br />[[teniposide]]<br />'''[[voriconazole]]''' |
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|- |
|- |
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!CYP |
!CYP |
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|- |
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|CYP2D6 |
|CYP2D6 |
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|amiodarone<br />bupropion<br />celecoxib<br />chlorpheniramine<br />chlorpromazine<br />cimetidine<br />citalopram<br />clemastine<br />clomipramine<br />cocaine<br />diphenhydramine<br />doxepin<br />doxorubicin<br />duloxetine<br />escitalopram |
|[[amiodarone]]<br />[[bupropion]]<br />[[celecoxib]]<br />[[chlorpheniramine]]<br />[[chlorpromazine]]<br />[[cimetidine]]<br />[[citalopram]]<br />[[clemastine]]<br />[[clomipramine]]<br />[[cocaine]]<br />[[diphenhydramine]]<br />[[doxepin]]<br />[[doxorubicin]]<br />[[duloxetine]]<br />[[escitalopram]] |
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|fluoxetine<br />hydroxyzine<br />metoclopramide<br />mibefradil<br />midodrine<br />moclobemide<br />paroxetine<br />perphenazine<br />quinidine<br />ranitidine<br />'''[[ritonavir]]'''<br />sertraline<br />terbinafine<br />ticlopidine |
|[[fluoxetine]]<br />[[hydroxyzine]]<br />[[metoclopramide]]<br />[[mibefradil]]<br />[[midodrine]]<br />[[moclobemide]]<br />[[paroxetine]]<br />[[perphenazine]]<br />[[quinidine]]<br />[[ranitidine]]<br />'''[[ritonavir]]'''<br />[[sertraline]]<br />[[terbinafine]]<br />[[ticlopidine]] |
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|dexamethasone<br />'''[[rifampin]]''' |
|[[dexamethasone]]<br />'''[[rifampin]]''' |
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|alprenolol<br />amitriptyline<br />amphetamine<br />aripiprazole<br />atomoxetine<br />carvedilol<br />chlorpheniramine<br />chlorpromazine<br />clomipramine<br />codeine |
|[[alprenolol]]<br />[[amitriptyline]]<br />[[amphetamine]]<br />[[aripiprazole]]<br />[[atomoxetine]]<br />[[carvedilol]]<br />[[chlorpheniramine]]<br />[[chlorpromazine]]<br />[[clomipramine]]<br />[[codeine]] |
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|debrisoquine<br />desipramine<br />dexfenfluramine<br />dextromethorphan<br />duloxetine<br />encainide<br />flecainide<br />fluoxetine<br />fluvoxamine<br />haloperidol |
|[[debrisoquine]]<br />[[desipramine]]<br />[[dexfenfluramine]]<br />[[dextromethorphan]]<br />[[duloxetine]]<br />[[encainide]]<br />[[flecainide]]<br />[[fluoxetine]]<br />[[fluvoxamine]]<br />[[haloperidol]] |
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|imipramine<br />lidocaine<br />methoxyamphetamine<br />metoclopramide<br />paroxetine<br />perphenazine<br />propafenone<br />S-metoprolol<br />thioridazine<br />timolol |
|[[imipramine]]<br />[[lidocaine]]<br />[[methoxyamphetamine]]<br />[[metoclopramide]]<br />[[paroxetine]]<br />[[perphenazine]]<br />[[propafenone]]<br />[[Metoprolol|S-metoprolol]]<br />[[thioridazine]]<br />[[timolol]] |
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!CYP |
!CYP |
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|CYP2E1 |
|CYP2E1 |
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|[[disulfiram]] |
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|ethanol<br />'''[[isoniazid]]''' |
|[[Alcohol use disorder|ethanol]]<br />'''[[isoniazid]]''' |
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|acetaminophen<br />chlorzoxazone<br />enflurane |
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|[[acetaminophen]]<br />[[chlorzoxazone]]<br />[[enflurane]] |
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|[[ethanol]]<br />[[halothane]]<br />[[isoflurane]] |
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|methoxyflurane<br />sevoflurane |
|[[methoxyflurane]]<br />[[sevoflurane]] |
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!CYP |
!CYP |
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|CYP3A |
|CYP3A |
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|amiodarone<br />aprepitant<br />cimetidine<br />'''[[clarithromycin]]'''<br />'''[[cobicistat]]'''<br />'''[[delavirdine]]'''<br />diltiazem<br />'''[[elvitegravir]]'''<br />'''[[erythromycin]]'''<br />'''[[fluconazole]]'''<br />fluvoxamine<br />gestodene<br />imatinib<br />'''[[indinavir]]''' |
|[[amiodarone]]<br />[[aprepitant]]<br />[[cimetidine]]<br />'''[[clarithromycin]]'''<br />'''[[cobicistat]]'''<br />'''[[delavirdine]]'''<br />[[diltiazem]]<br />'''[[elvitegravir]]'''<br />'''[[erythromycin]]'''<br />'''[[fluconazole]]'''<br />[[fluvoxamine]]<br />[[gestodene]]<br />[[imatinib]]<br />'''[[indinavir]]''' |
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|'''[[isavuconazonium]]'''<br />'''[[itraconazole]]'''<br />'''[[ketoconazole]]'''<br />mibefradil<br />mifepristone<br />nefazodone<br />'''[[nelfinavir]]'''<br />norfluoxetine<br />'''[[posaconazole]]'''<br />'''[[ritonavir]]'''<br />'''[[saquinavir]]'''<br />verapamil<br />'''[[voriconazole]]''' |
|'''[[isavuconazonium]]'''<br />'''[[itraconazole]]'''<br />'''[[ketoconazole]]'''<br />[[mibefradil]]<br />[[mifepristone]]<br />[[nefazodone]]<br />'''[[nelfinavir]]'''<br />[[norfluoxetine]]<br />'''[[posaconazole]]'''<br />'''[[ritonavir]]'''<br />'''[[saquinavir]]'''<br />[[verapamil]]<br />'''[[voriconazole]]''' |
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|barbiturates<br />carbamazepine<br />'''[[efavirenz]]'''<br />glucocorticoids<br />modafinil<br />nevirapine<br />oxcarbazepine<br />phenobarbital<br />phenytoin<br />pioglitazone<br />'''[[rifabutin]]'''<br />'''[[rifampin]]'''<br />St. |
|[[barbiturates]]<br />[[carbamazepine]]<br />'''[[efavirenz]]'''<br />[[glucocorticoids]]<br />[[modafinil]]<br />[[nevirapine]]<br />[[oxcarbazepine]]<br />[[phenobarbital]]<br />[[phenytoin]]<br />[[pioglitazone]]<br />'''[[rifabutin]]'''<br />'''[[rifampin]]'''<br />[[St. John's wort]] |
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|alfentanil<br />alprazolam<br />amlodipine<br />aprepitant<br />aripiprazole<br />'''[[artemisinin]]'''<br />astemizole<br />'''[[atazanavir]]'''<br />atorvastatin<br />'''[[bedaquiline]]'''<br />buspirone<br />cafergot<br />chlorpheniramine<br />cilostazol<br />'''[[clarithromycin]]'''<br />cocaine<br />cyclosporine<br />'''[[daclatasvir]]'''<br />'''[[dapsone]]'''<br />'''[[darunavir]]'''<br />dexamethasone<br />dextromethorphan<br />diltiazem<br />docetaxel<br />domperidone<br />'''[[elbasvir]]'''<br />eplerenone |
|[[alfentanil]]<br />[[alprazolam]]<br />[[amlodipine]]<br />[[aprepitant]]<br />[[aripiprazole]]<br />'''[[artemisinin]]'''<br />[[astemizole]]<br />'''[[atazanavir]]'''<br />[[atorvastatin]]<br />'''[[bedaquiline]]'''<br />[[buspirone]]<br />[[cafergot]]<br />[[chlorpheniramine]]<br />[[cilostazol]]<br />'''[[clarithromycin]]'''<br />[[cocaine]]<br />[[cyclosporine]]<br />'''[[daclatasvir]]'''<br />'''[[dapsone]]'''<br />'''[[darunavir]]'''<br />[[dexamethasone]]<br />[[dextromethorphan]]<br />[[diltiazem]]<br />[[docetaxel]]<br />[[domperidone]]<br />'''[[elbasvir]]'''<br />[[eplerenone]] |
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|'''[[erythromycin]]'''<br />estradiol<br />'''[[etravirine]]'''<br />felodipine<br />fentanyl<br />finasteride<br />'''[[fosamprenavir]]'''<br />'''[[grazoprevir]]'''<br />haloperidol<br />hydrocortisone<br />imitanib<br />'''[[indinavir]]'''<br />irinotecan<br />lidocaine<br />lovastatin<br />'''[[maraviroc]]'''<br />midazolam<br />nateglinide<br />'''[[nelfinavir]]'''<br />nifedipine<br />nisoldipine<br />nitrendipine<br />ondansetron<br />'''[[paritaprevir]]'''<br />pimozide<br />'''[[praziquantel]]''' |
|'''[[erythromycin]]'''<br />[[estradiol]]<br />'''[[etravirine]]'''<br />[[felodipine]]<br />[[fentanyl]]<br />[[finasteride]]<br />'''[[fosamprenavir]]'''<br />'''[[grazoprevir]]'''<br />[[haloperidol]]<br />[[hydrocortisone]]<br />[[imitanib]]<br />'''[[indinavir]]'''<br />[[irinotecan]]<br />[[lidocaine]]<br />[[lovastatin]]<br />'''[[maraviroc]]'''<br />[[midazolam]]<br />[[nateglinide]]<br />'''[[nelfinavir]]'''<br />[[nifedipine]]<br />[[nisoldipine]]<br />[[nitrendipine]]<br />[[ondansetron]]<br />'''[[paritaprevir]]'''<br />[[pimozide]]<br />'''[[praziquantel]]''' |
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|progesterone<br />quetiapine<br />quinidine<br />'''[[quinine]]'''<br />risperidone<br />'''[[ritonavir]]'''<br />salmeterol<br />'''[[saquinavir]]'''<br />sildenafil<br />'''[[simeprevir]]'''<br />simvastatin<br />sirolimus<br />tacrolimus<br />tadalafil<br />taxol<br />terfenadine<br />testosterone<br />'''[[tipranavir]]'''<br />trazodone<br />triazolam<br />vardenafil<br />verapamil<br />vincristine<br />zaleplon<br />ziprasidone<br />zolpidem |
|[[progesterone]]<br />[[quetiapine]]<br />[[quinidine]]<br />'''[[quinine]]'''<br />[[risperidone]]<br />'''[[ritonavir]]'''<br />[[salmeterol]]<br />'''[[saquinavir]]'''<br />[[sildenafil]]<br />'''[[simeprevir]]'''<br />[[simvastatin]]<br />[[sirolimus]]<br />[[tacrolimus]]<br />[[tadalafil]]<br />[[taxol]]<br />[[terfenadine]]<br />[[testosterone]]<br />'''[[tipranavir]]'''<br />[[trazodone]]<br />[[triazolam]]<br />[[vardenafil]]<br />[[verapamil]]<br />[[vincristine]]<br />[[zaleplon]]<br />[[ziprasidone]]<br />[[zolpidem]] |
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!CYP |
!CYP |
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[[Category: |
[[Category:Medications]] |
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