Nevirapine

From IDWiki

Pediatric Dosing

Neonatal HIV prophylaxis

  • Dosed by body surface area
  • ≥34 weeks gestation at birth: 150 mg/m2 PO once daily for 2 weeks, then q12h for 2 weeks
  • <34 weeks: 10 mg/m2 PO once daily for 2 weeks, then q12h for 2 weeks
  • Need to monitor serum trough levels at 7 and 14 days
  • For alternative three-dose regimen:
    • 8 mg/dose (1.5-2 kg) or 12 mg (>2 kg) within 48 hours of birth, repeated 48 hours after first dose and 96 hours after second dose