Thrombocytopenia: Difference between revisions
From IDWiki
No edit summary |
No edit summary |
||
| (3 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
==Differential Diagnosis== |
==Differential Diagnosis== |
||
*Pseudothrombocytopenia |
|||
*Decreased production |
*Decreased production |
||
**Viral infection |
**Viral infection |
||
| Line 6: | Line 7: | ||
*Destruction/Consumption |
*Destruction/Consumption |
||
**[[Immune-mediated thrombocytopenic purpura]] (ITP) |
**[[Immune-mediated thrombocytopenic purpura]] (ITP) |
||
***Primary ITP |
|||
***[[Hepatitis C]], [[HIV]], and [[Helicobacter pylori]] |
***[[Hepatitis C]], [[HIV]], and [[Helicobacter pylori]]; also [[CMV]], [[EBV]], [[VZV]], [[Zika virus]] |
||
***Medications: [[abciximab]], beta-lactams (including [[penicillins]] and [[cephalosporins]]), [[carbamazepine]], [[epifitabide]], gold compounds, [[Heparin-inducted thrombocytopenia|heparin]], [[linezolid]], [[MMR vaccine]], [[phenytoin]], [[piperacillin]], [[quinidine]], [[quinine]], [[rifampin]], sulfonamides (including [[TMP-SMX]]), [[valproic acid]], and [[vancomycin]] |
|||
***Autoimmune: [[antiphospholipid syndrome]], [[Evans syndrome]], [[IBD]], [[RA]], [[SLE]] |
|||
***[[CVID]] |
|||
***[[CLL]] |
|||
***[[Lymphoma]] |
|||
**[[Thrombotic microangiopathy]] |
**[[Thrombotic microangiopathy]] |
||
***[[TTP]]/[[HUS]], other TMAs |
***[[TTP]]/[[HUS]], other TMAs |
||
| Line 14: | Line 21: | ||
==Investigations== |
==Investigations== |
||
*Rule out secondary causes with |
*Rule out secondary causes with [[hepatitis C virus]], [[HIV]], and [[Helicobacter pylori]] serology |
||
[[Category:Hematology]] |
[[Category:Hematology]] |
||
Latest revision as of 17:01, 25 March 2024
Differential Diagnosis
- Pseudothrombocytopenia
- Decreased production
- Viral infection
- Malignancy
- Destruction/Consumption
- Immune-mediated thrombocytopenic purpura (ITP)
- Primary ITP
- Hepatitis C, HIV, and Helicobacter pylori; also CMV, EBV, VZV, Zika virus
- Medications: abciximab, beta-lactams (including penicillins and cephalosporins), carbamazepine, epifitabide, gold compounds, heparin, linezolid, MMR vaccine, phenytoin, piperacillin, quinidine, quinine, rifampin, sulfonamides (including TMP-SMX), valproic acid, and vancomycin
- Autoimmune: antiphospholipid syndrome, Evans syndrome, IBD, RA, SLE
- CVID
- CLL
- Lymphoma
- Thrombotic microangiopathy
- Immune-mediated thrombocytopenic purpura (ITP)
- Sequestration
Investigations
- Rule out secondary causes with hepatitis C virus, HIV, and Helicobacter pylori serology
