User contributions for Aidan

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A user with 10,390 edits. Account created on 11 August 2019.
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19 August 2025

  • 15:4815:48, 19 August 2025 diff hist +602 N Fidaxomicin Created page with "* Antibiotics indicated for Clostridioides difficile infection * Standard dose is 200 mg p.o. twice daily for 10 days * Pulse-tapered regimen is 200 mg once daily for 7 days followed by 200 mg fidaxomicin every other day for the remaining 13 dosesCiteRef::skinner2021a * In Ontario, EAP criteria for approval through the telephone request service includes: third or subsequent episode treated with vancomycin within 6 months; treatment failure despite at least 7 days..." current Tag: Visual edit

18 August 2025

  • 15:4615:46, 18 August 2025 diff hist +639 N Polatuzumab vedotin Created page with "* Anti-CD79b antibody with a humanized IgG1 monoclonal antibody and monomethyl auristatin E (MMAE, an antimitotic agent) * Indicated for diffuse large B-cell lymphoma * Adverse effects ** Include rash, anorexia, diarrhea, nausea/vomiting, fatigue, myelosuppression and opportunistic infections ** Infusion reactions can occur as late as 24 hours post-infusion ** Tumour lysis syndrome ** Hepatotoxicity, mostly low-grade and reversible ** Serious infections, includin..." current Tag: Visual edit

11 August 2025

5 August 2025

2 August 2025

1 August 2025

30 July 2025

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16 July 2025

7 July 2025

  • 23:4523:45, 7 July 2025 diff hist +632 N Quinine toxicity Created page with "== Background == * Quinine was originally an extract from the cinchona tree * Historically used to treat fevers and diarrhea, and eventually malaria * May be consumed recreationally in the form of tonic water === Pathophysiology === * It acts as a class qA antiarrhythmic, blocking both sodium and potassium, leading to long QRS and QT intervals * Toxic to the retina == Clinical Manifestations == * '''Cinchonism''': nausea, vomiting, and tinnitus ** Sweating, nausea,..." current Tag: Visual edit
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