Hypersensitivity reaction

Type	Mechanism	Examples
I	immediate IgE-mediated reaction	anaphylaxis, urticaria, angioedema, asthma, allergic rhinitis
II	antibody-mediated cytotoxic reaction	autoimmune hemolytic anemia, pemphigus vulgaris, Goodpasture syndrome, myasthenia gravis, Graves disease, chronic idiopathic urticaria
III	immune complex-mediated reaction	systemic lupus erythematosus, post-streptococcal glomerulonephritis, serum sickness, vasculitis
IV	delayed cell-mediated reaction	drug reaction with eosinophilia and systemic symptoms, multiple sclerosis, rheumatoid arthritis, sarcoidosis, tuberculosis
IVa	delayed Th1-mediated reaction	type 1 diabetes mellitus, contact dermatitis (with IVc)
IVb	delayed Th2-mediated reaction	persistent asthma and allergic rhinitis
IVc	delayed CD8 T-cell-mediated reaction	Stevens-Johnson syndrome and toxic epidermal necrolysis
IVd	delayed T-cell-mediated neutrophilic reaction	acute generalized exanthematous pustulosis, Behçet syndrome

Further Reading