Hypersensitivity reaction

Type		Mechanism	Examples
I		immediate IgE-mediated reaction	anaphylaxis, urticaria, angioedema, asthma, allergic rhinitis
II		antibody-mediated cytotoxic reaction	autoimmune hemolytic anemia, pemphigus vulgaris, Goodpasture syndrome, myasthenia gravis, Graves disease, chronic idiopathic urticaria
III		immune complex-mediated reaction	systemic lupus erythematosus, post-streptococcal glomerulonephritis, serum sickness, vasculitis
IV	IV	delayed cell-mediated reaction	drug reaction with eosinophilia and systemic symptoms, multiple sclerosis, rheumatoid arthritis, sarcoidosis, tuberculosis
	IVa	delayed Th1-mediated reaction	type 1 diabetes mellitus, contact dermatitis (with IVc)
	IVb	delayed Th2-mediated reaction	persistent asthma and allergic rhinitis
	IVc	delayed CD8 T-cell-mediated reaction	Stevens-Johnson syndrome and toxic epidermal necrolysis
	IVd	delayed T-cell-mediated neutrophilic reaction	acute generalized exanthematous pustulosis, Behçet syndrome

Further Reading