Acute generalized exanthematous pustulosis
From IDWiki
- Also known as a pustular drug eruption or toxic pustuloderma
- Typically triggered by medications
- Antibiotics (especially β-lactams) are most common trigger by far, followed by PPIs, NSAIDs, and herbal medicine
- Characteristic rash is diffuse, erythematous, with many pinpoint pustules
- Typically starts in face or intertriginous areas, then spreads centrally
- Can involve palms and soles but not mucosa
- May be followed by desquamation
- Can also have systemic symptoms
- May have mild liver enzyme abnormalities
