Splenomegaly: Difference between revisions
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==Background== |
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*'''Hypersplenism''' is defined as splenomegaly with any of: anemia, leukopenia, or thrombocytopenia, which are expected to correct after splenectomy |
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**All patients with hypersplenism have splenomegaly, but not all patients with splenomegaly have hypersplenism |
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**Mostly secondary to other process, but rarely can be primary |
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==Differential Diagnosis== |
==Differential Diagnosis== |
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***Parasite: [[toxoplasmosis]] |
***Parasite: [[toxoplasmosis]] |
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**Subacute or chronic |
**Subacute or chronic |
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***Subacute bacterial endocarditis |
***[[Subacute bacterial endocarditis]] |
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***Tuberculosis |
***[[Tuberculosis]] |
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***Malaria |
***[[Malaria]] |
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***Visceral leishmaniasis |
***[[Visceral leishmaniasis]] |
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***Fungal infections |
***Fungal infections |
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*Inflammatory |
*Inflammatory |
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Latest revision as of 15:32, 30 July 2020
Background
- Hypersplenism is defined as splenomegaly with any of: anemia, leukopenia, or thrombocytopenia, which are expected to correct after splenectomy
- All patients with hypersplenism have splenomegaly, but not all patients with splenomegaly have hypersplenism
- Mostly secondary to other process, but rarely can be primary
Differential Diagnosis
- See also massive splenomegaly
- Infectious
- Acute
- Viral: viral hepatitis, infectious mononucleosis, CMV
- Bacterial: sepsis, salmonellosis, brucellosis, splenic abscess
- Parasite: toxoplasmosis
- Subacute or chronic
- Subacute bacterial endocarditis
- Tuberculosis
- Malaria
- Visceral leishmaniasis
- Fungal infections
- Acute
- Inflammatory
- Congestive
- Intrahepatic: cirrhosis
- Extrahepatic:
- Heart failure
- Hematologic
- RBC disorders
- Neoplasia
- Genetic/metabolic
- Other
- Amyloidosis
- Splenic cyst
