Antifungal spectrum of activity

Organism	AmB	Triazoles				Echinocandins			Flucyt
		Fluc	Itra	Vori	Posa	Anidula	Caspo	Mica
Aspergillus	+	–	+	+	+	+	+	+	–
A. flavus	±	–	+	+	+	+	+	+	–
A. fumigatus	+	–	+	+	+	+	+	+	–
A. terreus	–	–	+	+	+	+	+	+	–
A. niger	+	–	±	+	+	+	+	+	–
Candida	+	+	+	+	+	+	+	+	+
C. albicans	+	+	+	+	+	+	+	+	+
C. glabrata	+	±	±	+	+	+	+	+	+
C. krusei	+	–	±	+	+	+	+	+	±
C. lusitaniae	–	+	+	+	+	+	+	+	+
C. parapsilosis	+	+	+	+	+	±	±	±	+
C. tropicalis	+	+	+	+	+	+	+	+	+
Cryptococcus neoformans	+	+	+	+	+	–	–	–	+
Coccidioides	+	+	+	+	+	±	±	±	–
Blastomyces	+	+	+	+	+	±	±	±	–
Histoplasma	+	+	+	+	+	±	±	±	–
Fusarium	±	–	–	+	+	–	–	–	–
Scedosporium apiospermum	±	–	±	+	+	–	–	–	–
Scedosporium prolificans	–	–	–	±	±	–	–	–	–
Zygomycetes	±	–	–	–	+	–	–	–	–

• Aspergillus ustus is resistant to azoles and echinocandins, and variable resistance to amphotericin (though still susceptible to terbinafine)

Source: Elizabeth S. Dodds Ashley, Russell Lewis, James S. Lewis, Craig Martin, David Andes, Pharmacology of Systemic Antifungal Agents, Clinical Infectious Diseases, Volume 43, Issue Supplement_1, 1 August 2006, Pages S28–S39, https://doi.org/10.1086/504492