Cladophialophora

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Cladophialophora / (Redirected from Cladophialophora bantiana)

Background

Microbiology

Epidemiology

  • More common in India
  • Associated with soil, bark, or carbon-rich environments, like coal mining or sawdust
  • More common in gardeners and farmers, but not exclusive
  • Unclear if acquired by inhalation or implantation

Clinical Manifestations

Diagnosis

  • Culture
    • Microscopy
      • Long, delicate, branching chains of hydrophobic brown conidia and lacking yeast cells, with brown septate hyphae
    • The species (and Cladosporium) are differentiated by physiologic tests include temperature tolerance, gelatin liquefaction, cycloheximide growth, urease test, and the nitrate test
  • Histopathology is necessary for subcutaneous infections

Management

References

  1. ^  Marçal Mariné, F. Javier Pastor, Josep Guarro. Combined antifungal therapy in a murine model of disseminated infection byCladophialophora bantiana. Medical Mycology. 2009;47(1):45-49. doi:10.1080/13693780802526840.
  2. ^  Stefan Schwartz, Oliver A Cornely, Kamal Hamed, Francisco M Marty, Johan Maertens, Galia Rahav, Raoul Herbrecht, Werner J Heinz. Isavuconazole for the treatment of patients with invasive fungal diseases involving the central nervous system. Medical Mycology. 2019. doi:10.1093/mmy/myz103.