Splenomegaly: Difference between revisions
From IDWiki
No edit summary |
(→) |
||
| Line 1: | Line 1: | ||
| − | == |
+ | ==Background== |
| − | * |
+ | *'''Hypersplenism''' is defined as splenomegaly with any of: anemia, leukopenia, or thrombocytopenia, which are expected to correct after splenectomy |
| − | ** |
+ | **All patients with hypersplenism have splenomegaly, but not all patients with splenomegaly have hypersplenism |
| − | ** |
+ | **Mostly secondary to other process, but rarely can be primary |
==Differential Diagnosis== |
==Differential Diagnosis== |
||
| Line 14: | Line 14: | ||
***Parasite: [[toxoplasmosis]] |
***Parasite: [[toxoplasmosis]] |
||
**Subacute or chronic |
**Subacute or chronic |
||
| − | ***Subacute bacterial endocarditis |
+ | ***[[Subacute bacterial endocarditis]] |
| − | ***Tuberculosis |
+ | ***[[Tuberculosis]] |
| − | ***Malaria |
+ | ***[[Malaria]] |
| − | ***Visceral leishmaniasis |
+ | ***[[Visceral leishmaniasis]] |
***Fungal infections |
***Fungal infections |
||
*Inflammatory |
*Inflammatory |
||
Latest revision as of 11:32, 30 July 2020
Background
- Hypersplenism is defined as splenomegaly with any of: anemia, leukopenia, or thrombocytopenia, which are expected to correct after splenectomy
- All patients with hypersplenism have splenomegaly, but not all patients with splenomegaly have hypersplenism
- Mostly secondary to other process, but rarely can be primary
Differential Diagnosis
- See also massive splenomegaly
- Infectious
- Acute
- Viral: viral hepatitis, infectious mononucleosis, CMV
- Bacterial: sepsis, salmonellosis, brucellosis, splenic abscess
- Parasite: toxoplasmosis
- Subacute or chronic
- Subacute bacterial endocarditis
- Tuberculosis
- Malaria
- Visceral leishmaniasis
- Fungal infections
- Acute
- Inflammatory
- Congestive
- Intrahepatic: cirrhosis
- Extrahepatic:
- Heart failure
- Hematologic
- RBC disorders
- Neoplasia
- Genetic/metabolic
- Other
- Amyloidosis
- Splenic cyst
