Itraconazole: Difference between revisions
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+ | == Background == |
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* Azole antifungal |
* Azole antifungal |
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* Indications include {{#ask: [[Is treated by::itraconazole]]}} |
* Indications include {{#ask: [[Is treated by::itraconazole]]}} |
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+ | == Dosing == |
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⚫ | |||
+ | |||
+ | * Typical dose: 200 mg p.o. twice daily |
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+ | * May be used once daily for the treatment of some [[Candida|candidal]] or [[dermatophytes|dermatophytic]] infections |
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+ | |||
+ | == Safety == |
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+ | |||
⚫ | |||
* Should be measured 5 to 7 days after starting or changing the dose, or when interacting medications are changed |
* Should be measured 5 to 7 days after starting or changing the dose, or when interacting medications are changed |
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* Target in prophylaxis is a trough ot 0.5 mg/L |
* Target in prophylaxis is a trough ot 0.5 mg/L |
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* Target in treatment is a trough >0.5 mg/L |
* Target in treatment is a trough >0.5 mg/L |
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− | == Adverse |
+ | === Adverse Drug Reactions === |
− | * [[ |
+ | * [[Adverse drug reaction::Headache]] |
− | * [[ |
+ | * [[Adverse drug reaction::Relative adrenal insufficiency]] |
− | * [[ |
+ | * [[Adverse drug reaction::Hepatotoxicity]] |
− | * [[ |
+ | * [[Adverse drug reaction::QTc prolongation]] |
− | [[Category: |
+ | [[Category:Triazoles]] |
Latest revision as of 12:52, 2 January 2024
Background
- Azole antifungal
- Indications include Alternaria, Blastomyces dermatitidis, Chromoblastomycosis, Coccidioides immitis, Cryptococcus, Entomophthoromycotina, Exophiala, Exserohilum, Fonsecaea, Histoplasma capsulatum, Mycetoma, Paracoccidioides brasiliensis, Sappinia diploidea, Sporothrix schenckii
Dosing
- Typical dose: 200 mg p.o. twice daily
- May be used once daily for the treatment of some candidal or dermatophytic infections
Safety
Therapeutic Drug Monitoring
- Should be measured 5 to 7 days after starting or changing the dose, or when interacting medications are changed
- Target in prophylaxis is a trough ot 0.5 mg/L
- Target in treatment is a trough >0.5 mg/L