Itraconazole: Difference between revisions
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| + | == Background == |
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* Azole antifungal |
* Azole antifungal |
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* Indications include {{#ask: [[Is treated by::itraconazole]]}} |
* Indications include {{#ask: [[Is treated by::itraconazole]]}} |
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| + | == Dosing == |
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| + | |||
| + | * Typical dose: 200 mg p.o. twice daily |
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| + | * May be used once daily for the treatment of some [[Candida|candidal]] or [[dermatophytes|dermatophytic]] infections |
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| + | |||
| + | == Safety == |
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* Should be measured 5 to 7 days after starting or changing the dose, or when interacting medications are changed |
* Should be measured 5 to 7 days after starting or changing the dose, or when interacting medications are changed |
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* Target in prophylaxis is a trough ot 0.5 mg/L |
* Target in prophylaxis is a trough ot 0.5 mg/L |
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* Target in treatment is a trough >0.5 mg/L |
* Target in treatment is a trough >0.5 mg/L |
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| − | == Adverse Drug Reactions == |
+ | === Adverse Drug Reactions === |
* [[Adverse drug reaction::Headache]] |
* [[Adverse drug reaction::Headache]] |
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* [[Adverse drug reaction::Relative adrenal insufficiency]] |
* [[Adverse drug reaction::Relative adrenal insufficiency]] |
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Latest revision as of 12:52, 2 January 2024
Background
- Azole antifungal
- Indications include Alternaria, Blastomyces dermatitidis, Chromoblastomycosis, Coccidioides immitis, Cryptococcus, Entomophthoromycotina, Exophiala, Exserohilum, Fonsecaea, Histoplasma capsulatum, Mycetoma, Paracoccidioides brasiliensis, Sappinia diploidea, Sporothrix schenckii
Dosing
- Typical dose: 200 mg p.o. twice daily
- May be used once daily for the treatment of some candidal or dermatophytic infections
Safety
Therapeutic Drug Monitoring
- Should be measured 5 to 7 days after starting or changing the dose, or when interacting medications are changed
- Target in prophylaxis is a trough ot 0.5 mg/L
- Target in treatment is a trough >0.5 mg/L
