Cystic fibrosis pulmonary exacerbation: Difference between revisions

Revision as of 11:12, 20 June 2023

Increased cough and sputum production
Increased dyspnea
Poor appetite, weight loss, occasionally fever, fatigue, reduction in pulmonary function, increased hemoptysis, change in chest radiographic findings, or change in chest physical examination findings (increased rales or rhonchi, decreased air exchange, increased use of accessory muscles of respiration)

@@ Line 8: / Line 8: @@
 * Get sputum cultures
-* See [[Cystic fibrosis (CF) antibiotic dosing]]
+* See [[Cystic fibrosis antibiotic dosing|antibiotic dosing in cystic fibrosis]]
-* ''Burkholderia cepacia''
+* [[Burkholderia cepacia complex|Burkholderia cepacia]]
 ** Most important organism to cover, if present
-** Meropenem, ceftazidime, tobi, doxy, Septra, levo
+** [[Meropenem]], [[ceftazidime]], inhaled [[tobramycin]], [[doxycycline]], [[TMP-SMX]], [[levofloxacin]]
-* ''Pseudomonas''
+* [[Pseudomonas aeruginosa]]
 ** Double coverage
-** Beta-lactam plus another (quinolone, colistin, chloramphenicol, aminoglycoside)
+** Beta-lactam plus another ([[fluoroquinolone]], [[colistin]], [[chloramphenicol]], [[aminoglycoside]])
 ** Treat for 10-14 days and repeat FPTs
-* ''Stenotrophomonas''
+* [[Stenotrophomonas maltophilia|Stenotrophomonas]]
-** Septra, doxycycline, tigecycline, colistin, sometimes levofloxacin
+** [[TMP-SMX]], [[doxycycline]], [[tigecycline]], [[colistin]], sometimes [[levofloxacin]]
-* ''Staph. aureus''
+* [[Staphylococcus aureus]]
-** MSSA: cloxacillin, ceftazidime, Septra, doxycycline, meropenem
+** MSSA: [[cloxacillin]], [[ceftazidime]], [[TMP-SMX]], [[doxycycline]], [[meropenem]]
-** MRSA: vancomycin, tigecycline, linezolid, daptomycin, doxycycline, Septra
+** MRSA: [[vancomycin]], [[tigecycline]], [[linezolid]], [[daptomycin]], [[doxycycline]], [[TMP-SMX]]
 [[Category:Respirology]]