Baltimore classification of viruses

• Classification based on the way that the virus creates mRNA

Class I: dsDNA

• Adenoviridae (unenveloped): adenovirus
• Papillomaviridae (unenveloped): human papillomavirus
• Polyomaviridae (unenveloped): JC virus, BK virus
• Herpesviridae (enveloped)
  • Herpes simplex virus
  • Varicella-zoster virus
  • Epstein-Barr virus (EBV)
  • Cytomegalovirus (CMV)
• Orthopoxviridae (enveloped): smallpox virus, monkeypox virus

Class II: ssDNA

• Parvoviridae: parvovirus B19

Class III: dsRNA

• Reoviridae (unenveloped): rotavirus

Class IV: (+)ssRNA

• Picornaviridae (unenveloped)
  • Enterovirus
    • Coxsackie virus
    • Rhinovirus
  • Hepatovirus (Hepatitis A)
• Caliciviridae (unenveloped): norovirus
• Togaviridae (enveloped): Chikungunya virus
• Matonaviridae (enveloped): rubella virus
• Flaviviridae (enveloped)
  • Dengue virus
  • Hepatitis C virus
  • Yellow fever virus
  • Zika virus
• Coronaviridae (enveloped): seasonal coronaviruses, SARS-CoV, SARS-CoV-2, MERS-CoV
• Hepeviridae (unenveloped): hepatitis E virus

Class V: (–)ssRNA

• Orthomyxoviridae (enveloped): influenza virus
• Paramyxoviridae (enveloped)
  • Measles virus
  • Mumps virus
  • Parainfluenza virus
• Pneumoviridae (enveloped)
  • Respiratory syncytial virus (RSV)
  • Human metapneumovirus
• Rhabdoviridae (enveloped): rabies virus
• Filoviridae (enveloped)
  • Ebola virus
  • Marburg virus
• Arenaviridae (enveloped):
  • Lassa virus
  • Lymphocytic choriomeningitis virus

Class VI: ssRNA-RT

• Retroviridae (enveloped)
  • Human immunodeficiency virus (HIV)
  • Human T-lymphotropic virus (HTLV)

Class VII: dsDNA-RT

• Hepadnaviruses (enveloped): Hepatitis B virus