| CYP | Inhibitors | Inducers | Substrates | |||
|---|---|---|---|---|---|---|
| CYP1A2 | amiodarone cimetidine ciprofloxacin |
fluvoxamine interferon methoxsalen |
cigarette smoking marijuana smoking modafinil nafcillin |
amitriptyline caffeine clomipramine clozapine cyclobenzaprine estradiol fluvoxamine haloperidol |
mexiletine naproxen olanzapine ondansetron phenacetine propranolol riluzole ropivacaine |
tacrine theophylline tizanidine verapamil R-warfarin zileuton zolmitriptan |
| CYP | Inhibitors | Inducers | Substrates | |||
| CYP2B6 | ticlopidine | thiotepa | phenobarbital rifampin |
bupropion cyclophosphamide |
efavirenz ifosfamide |
methadone |
| CYP | Inhibitors | Inducers | Substrates | |||
| CYP2C8 | gemfibrozil montelukast pioglitazone |
quercetin rosiglitazone trimethoprim |
rifampin | amodiaquine dasabuvir |
cerivastatin paclitaxel |
torsemide repaglinide |
| CYP | Inhibitors | Inducers | Substrates | |||
| CYP2C9 | amiodarone fenofibrate fluconazole fluvastatin fluvoxamine isoniazid |
probenecid sertraline sulfamethoxazole teniposide voriconazole zafirlukast |
rifampin secorbarbital |
amitriptyline celecoxib diclofenac fluoxetine fluvastatin glipizide glyburide ibuprofen |
irbesartan lornoxicam losartan meloxicam nateglinide omeprazole phenytoin |
piroxicam rosiglitazone rosuvastatin S-warfarin tamoxifen tolbutamide torsemide |
| CYP | Inhibitors | Inducers | Substrates | |||
| CYP2C19 | cimetidine esomeprazole felbamate fluoxetine fluvoxamine indomethacin ketoconazole lansoprazole |
modafinil omeprazole oxcarbazepine pantoprazole probenecid rabeprazole ticlopidine topiramate |
carbamazepine norethindrone prednisone rifampin |
carisoprodol chloramphenicol citalopram clomipramine cyclophosphamide esomeprazole hexobarbital indomethacin |
lansoprazole moclobemide nelfinavir nilutamide omeprazole pantoprazole phenobarbital phenytoin |
primidone progesterone proguanil propranolol rabeprazole teniposide voriconazole |
| CYP | Inhibitors | Inducers | Substrates | |||
| CYP2D6 | amiodarone bupropion celecoxib chlorpheniramine chlorpromazine cimetidine citalopram clemastine clomipramine cocaine diphenhydramine doxepin doxorubicin duloxetine escitalopram |
fluoxetine hydroxyzine metoclopramide mibefradil midodrine moclobemide paroxetine perphenazine quinidine ranitidine ritonavir sertraline terbinafine ticlopidine |
dexamethasone rifampin |
alprenolol amitriptyline amphetamine aripiprazole atomoxetine carvedilol chlorpheniramine chlorpromazine clomipramine codeine |
debrisoquine desipramine dexfenfluramine dextromethorphan duloxetine encainide flecainide fluoxetine fluvoxamine haloperidol |
imipramine lidocaine methoxyamphetamine metoclopramide paroxetine perphenazine propafenone S-metoprolol thioridazine timolol |
| CYP | Inhibitors | Inducers | Substrates | |||
| CYP2E1 | disulfiram | ethanol isoniazid |
acetaminophen chlorzoxazone enflurane |
ethanol halothane isoflurane |
methoxyflurane sevoflurane | |
| CYP | Inhibitors | Inducers | Substrates | |||
| CYP3A | amiodarone aprepitant cimetidine clarithromycin cobicistat delavirdine diltiazem elvitegravir erythromycin fluconazole fluvoxamine gestodene imatinib indinavir |
isavuconazonium itraconazole ketoconazole mibefradil mifepristone nefazodone nelfinavir norfluoxetine posaconazole ritonavir saquinavir verapamil voriconazole |
barbiturates carbamazepine efavirenz glucocorticoids modafinil nevirapine oxcarbazepine phenobarbital phenytoin pioglitazone rifabutin rifampin St. John’s wort |
alfentanil alprazolam amlodipine aprepitant aripiprazole artemisinin astemizole atazanavir atorvastatin bedaquiline buspirone cafergot chlorpheniramine cilostazol clarithromycin cocaine cyclosporine daclatasvir dapsone darunavir dexamethasone dextromethorphan diltiazem docetaxel domperidone elbasvir eplerenone |
erythromycin estradiol etravirine felodipine fentanyl finasteride fosamprenavir grazoprevir haloperidol hydrocortisone imitanib indinavir irinotecan lidocaine lovastatin maraviroc midazolam nateglinide nelfinavir nifedipine nisoldipine nitrendipine ondansetron paritaprevir pimozide praziquantel |
progesterone quetiapine quinidine quinine risperidone ritonavir salmeterol saquinavir sildenafil simeprevir simvastatin sirolimus tacrolimus tadalafil taxol terfenadine testosterone tipranavir trazodone triazolam vardenafil verapamil vincristine zaleplon ziprasidone zolpidem |
| CYP | Inhibitors | Inducers | Substrates | |||
