Chromobacterium violaceum: Difference between revisions
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Chromobacterium violaceum
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*Mostly tropical or subtropical areas, especially southeast Asia |
*Mostly tropical or subtropical areas, especially southeast Asia |
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*Also in southeast US, most commonly Florida |
*Also in southeast US, most commonly Florida |
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*CGD is a risk factor for opportunistic infection, as is G6PD deficiency |
*[[CGD]] is a risk factor for opportunistic infection, as is [[G6PD deficiency]] |
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==Clinical Manifestations== |
==Clinical Manifestations== |
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*Causes wound infections following contaminated water exposure |
*Causes wound infections following contaminated water exposure |
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*Always with systemic features, including fever (100%) and sepsis (82%) |
*Always with systemic features, including [[Causes::fever]] (100%) and [[Causes::sepsis]] (82%) |
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*Often |
*Often [[Causes::bacteremia]] (60%) and can involve visceral organs (51%), especially lung and liver |
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*High mortality (53%) |
*High mortality (53%) |
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Revision as of 11:05, 29 August 2020
Background
Microbiology
- Gram-negative bacterium
- Colonies are deep purple to black due to the presence of the violacein pigment
- Found in water
Epidemiology
- Mostly tropical or subtropical areas, especially southeast Asia
- Also in southeast US, most commonly Florida
- CGD is a risk factor for opportunistic infection, as is G6PD deficiency
Clinical Manifestations
- Causes wound infections following contaminated water exposure
- Always with systemic features, including fever (100%) and sepsis (82%)
- Often bacteremia (60%) and can involve visceral organs (51%), especially lung and liver
- High mortality (53%)
Differential Diagnosis
- Includes other causes of skin and soft tissue infection after water exposure
- Common bugs: Staphylococcus aureus, Streptococcus pyogenes, other streptococci, Klebsiella species, Pseudomonas aeruginosa, Escherichia coli, and polymicrobial infections
- Uniquely marine bacteria: Aeromonas species, Vibrio vulnificus, Shewanella species, Edwardsiella species, Chromobacterium species
- Others: Burkholderia pseudomallei, non-tuberculous mycobacteria, and some fungi
Management
Further Reading
- Chromobacterium violaceum infection: a clinical review of an important but neglected infection. J Chin Med Assoc. 2011;74(10):435-41.
