Hypersensitivity reaction: Difference between revisions
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|delayed cell-mediated reaction |
|delayed cell-mediated reaction |
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|[[drug reaction with eosinophilia and systemic symptoms]], [[multiple sclerosis]], [[rheumatoid arthritis]], [[sarcoidosis]], [[tuberculosis]] |
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|IVa |
|IVa |
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|delayed Th1-mediated reaction |
|delayed Th1-mediated reaction |
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|[[type 1 diabetes mellitus]], [[contact dermatitis]] (with IVc) |
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|IVb |
|IVb |
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|delayed Th2-mediated reaction |
|delayed Th2-mediated reaction |
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|persistent [[asthma]] and [[allergic rhinitis]] |
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|IVc |
|IVc |
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|delayed CD8 T-cell-mediated reaction |
|delayed CD8 T-cell-mediated reaction |
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|[[Stevens-Johnson syndrome]] and [[toxic epidermal necrolysis]] |
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|IVd |
|IVd |
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|delayed T-cell-mediated neutrophilic reaction |
|delayed T-cell-mediated neutrophilic reaction |
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|[[acute generalized exanthematous pustulosis]], [[Behçet syndrome]] |
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== Further Reading == |
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* Classification of hypersensitivity reactions. ''Allergy Asthma Proc''. 2012;33:S96-S99. doi: [https://doi.org/10.2500/aap.2012.33.3561 10.2500/aap.2012.33.3561] |
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[[Category:Allergy]] |
[[Category:Allergy]] |
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Revision as of 18:04, 25 February 2021
| Type | Mechanism | Examples |
|---|---|---|
| I | immediate IgE-mediated reaction | anaphylaxis, allergies, asthma |
| II | antibody-mediated cytotoxic reaction | autoimmune hemolytic anemia, pemphigus vulgaris, Goodpasture syndrome, myasthenia gravis, Graves disease |
| III | immune complex-mediated reaction | systemic lupus erythematosus, post-streptococcal glomerulonephritis, serum sickness |
| IV | delayed cell-mediated reaction | drug reaction with eosinophilia and systemic symptoms, multiple sclerosis, rheumatoid arthritis, sarcoidosis, tuberculosis |
| IVa | delayed Th1-mediated reaction | type 1 diabetes mellitus, contact dermatitis (with IVc) |
| IVb | delayed Th2-mediated reaction | persistent asthma and allergic rhinitis |
| IVc | delayed CD8 T-cell-mediated reaction | Stevens-Johnson syndrome and toxic epidermal necrolysis |
| IVd | delayed T-cell-mediated neutrophilic reaction | acute generalized exanthematous pustulosis, Behçet syndrome |
Further Reading
- Classification of hypersensitivity reactions. Allergy Asthma Proc. 2012;33:S96-S99. doi: 10.2500/aap.2012.33.3561
