Baltimore classification of viruses

• Classification based on the way that the virus creates mRNA

Class I: dsDNA

• Adenoviridae (unenveloped): adenovirus
• Herpesviridae (enveloped)
  • Herpes simplex virus
  • Varicella-zoster virus
  • Epstein-Barr virus (EBV)
  • Cytomegalovirus (CMV)
• Papovaviridae (unenveloped): papillomavirus
• Orthopoxviridae (complex coats): smallpox virus

Class II: ssDNA

• Parvoviridae: parvovirus B19

Class III: dsRNA

• Reoviridae (unenveloped): rotavirus

Class IV: (+)ssRNA

• Picornaviridae (unenveloped)
  • Enterovirus
  • Rhinovirus
  • Hepatovirus (Hepatitis A)
  • Coxsackie virus
• Caliciviridae (unenveloped): norovirus
• Togaviridae (enveloped): rubella virus
• Flaviviridae (enveloped)
  • Dengue virus
  • Hepatitis C virus
  • Yellow fever virus
  • Zika virus
• Coronaviridae (enveloped): corona virus
• Hepeviridae (unenveloped): hepatitis E virus

Class V: (–)ssRNA

• Orthomyxoviridae (enveloped): influenza virus
• Paramyxoviridae (enveloped)
  • Measles virus
  • Mumps virus
  • Respiratory syncitial virus (RSV)
• Rhabdoviridae (enveloped): rabies virus
• Filoviridae (enveloped)
  • Ebola virus
  • Marburg virus

Class VI: ssRNA-RT

• Retroviridae (enveloped)
  • Human immunodeficiency virus (HIV)
  • Human T-lymphotropic virus (HTLV)

Class VII: dsDNA-RT

• Hepadnaviruses (enveloped): Hepatitis B virus