Multidrug-resistant organism: Difference between revisions
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=== European CDC Definitions === |
=== European CDC Definitions === |
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* Defined by the European CDC |
* Defined by the European CDC[[CiteRef::magiorakos2012mu]] as non-susceptibility to at least one agent in three or more categories of antimicrobials, with the categories varying by organism |
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* Multidrug resistant (MDR) is non-susceptible to at least 1 agent in at least 3 categories |
* Multidrug resistant (MDR) is non-susceptible to at least 1 agent in at least 3 categories |
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** For [[Staphylococcus aureus]], it automatically includes MRSA, but requires resistance in >3 categories |
** For [[Staphylococcus aureus]], it automatically includes MRSA, but requires resistance in >3 categories |
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Latest revision as of 17:08, 27 September 2024
Background
- Microorganisms, predominantly bacteria, that are resistant to one or more classes of antimicrobial agents
- Definition varies from hospital to hospital or country to country
European CDC Definitions
- Defined by the European CDC1 as non-susceptibility to at least one agent in three or more categories of antimicrobials, with the categories varying by organism
- Multidrug resistant (MDR) is non-susceptible to at least 1 agent in at least 3 categories
- For Staphylococcus aureus, it automatically includes MRSA, but requires resistance in >3 categories
- Extensively drug-resistant (XDR) is non-susceptible to at least 1 agent in all but 2 categories
- Pan-drug resistant (PDR) is non-susceptible to all listed agents
- For species with intrinsic resistance to a category or agent, it should be excluded before counting
