Dengue virus: Difference between revisions
From IDWiki
(→) |
(→) |
||
| Line 20: | Line 20: | ||
==Differential Diagnosis== |
==Differential Diagnosis== |
||
| + | *[[Zika virus]] |
||
| − | *Differential also include whichever [[rickettsioses]] are endemic to the area visited |
||
| + | *[[Chikungunya virus]] |
||
| + | *[[Rickettsiae]] |
||
{| class="wikitable" |
{| class="wikitable" |
||
Revision as of 14:00, 22 August 2020
Background
Microbiology
- Single-stranded positive-sense RNA virus
- Member of the Flaviviridae
Epidemiology
- Endemic in tropics worldwide, with almost half of the world's population at risk of infection
- Transmitted by Aedes aegypti and Aedes albopictus
Clinical Manifestations
- Incubation period of 4 to 7 days
- Classic presentation includes fever, headache (especially retroorbital), diffuse arthralgias ("breakbone fever"), and rash
- Often has thrombocytopenia
- With repeated infections, can progress to hemorrhagic fever and shock
Differential Diagnosis
| Feature | Dengue | Zika | Chikungunya |
|---|---|---|---|
| Fever | +++ | ++ | +++ |
| Rash | + | +++ | ++ |
| Conjunctivitis | – | ++ | – |
| Arthralgia | + | ++ | +++ |
| Myalgia | ++ | + | + |
| Headache | ++ | + | ++ |
| Hemorrhage | ++ | – | – |
| Shock | + | – | – |
Management
- Supportive
