Corynebacterium jeikeium: Difference between revisions

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Corynebacterium jeikeium
(Created page with "* Species of ''Corynebacterium'' that causes opportunistic infections, most closely associated with hematologic stem cell transplant patients * Clinical presentations incl...")
 
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* Species of ''[[Corynebacterium]]'' that causes opportunistic infections, most closely associated with hematologic stem cell transplant patients
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* Species of [[Genus::Corynebacterium]] that causes opportunistic infections, most closely associated with hematologic stem cell transplant patients
 
* Clinical presentations include bacteremia, prosthetic valve endocarditis, meningitis, and peritonitis
  
* Clinical presentations include bacteremia, prosthetic valve endocarditis, meningitis, and peritonitis
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* Essentially universally susceptible to [[vancomycin]] and [[linezolid]]
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* High rates of resistance to beta lactams; may be fluoroquinolone or tetracycline susceptible<ref name=":0">Neemuchwala A, Soares D, Ravirajan V, Marchand-Austin A, Kus JV, Patel SN. ''In Vitro'' Antibiotic Susceptibility Pattern of Non-diphtheriae Corynebacterium Isolates in Ontario, Canada, from 2011 to 2016. Antimicrob Agents Chemother. 2018 Mar 27;62(4):e01776-17. doi: [https://doi.org/10.1128/aac.01776-17 10.1128/AAC.01776-17]. PMID: [https://pubmed.ncbi.nlm.nih.gov/29339389/ 29339389]; PMCID: [http://www.ncbi.nlm.nih.gov/pmc/articles/pmc5914010/ PMC5914010].</ref>
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{| class="wikitable sortable"
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|+From <ref name=":0" />
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!Antibiotic
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!Isolates
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!% Susceptible
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|-
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|[[Penicillin]]
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|76
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|0
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|-
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|[[Ampicillin]]
  +
|76
  +
|ND
  +
|-
  +
|[[Oxacillin]]
  +
|76
  +
|ND
  +
|-
  +
|[[Erythromycin]]
  +
|76
  +
|11.8
  +
|-
  +
|[[Clindamycin]]
  +
|76
  +
|2.6
  +
|-
  +
|[[Ciprofloxacin]]
  +
|75
  +
|35.5
  +
|-
  +
|[[Levofloxacin]]
  +
|75
  +
|ND
  +
|-
  +
|[[Moxifloxacin]]
  +
|76
  +
|35.5
  +
|-
  +
|'''[[Tetracycline]]'''
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|'''76'''
  +
|'''92.1'''
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|-
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|'''[[Vancomycin]]'''
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|'''76'''
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|'''100'''
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|-
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|[[Trimethoprim-sulfamethoxazole]]
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|76
  +
|18.4
  +
|-
  +
|[[Tigecycline]]
  +
|76
  +
|ND
  +
|-
  +
|'''[[Rifampin]]'''
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|'''76'''
  +
|'''97.4'''
  +
|-
  +
|'''[[Quinupristin-dalfopristin]]'''
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|'''76'''
  +
|'''89.5'''
  +
|-
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|'''[[Linezolid]]'''
  +
|'''76'''
  +
|'''100'''
  +
|-
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|'''[[Gentamicin]]'''
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|'''76'''
  +
|'''81.6'''
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|-
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|'''[[Daptomycin]]'''
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|'''75'''
  +
|'''89.5'''
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|-
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|[[Chloramphenicol]]
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|75
  +
|ND
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|-
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|[[Nitrofurantoin]]
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|76
  +
|ND
  +
|}
 
{{DISPLAYTITLE:''Corynebacterium jeikeium''}}
  
{{DISPLAYTITLE:''Corynebacterium jeikeium''}}
 
[[Category:Gram-positive bacilli]]
  
[[Category:Gram-positive bacilli]]

Latest revision as of 11:09, 27 September 2023

  • Species of Corynebacterium that causes opportunistic infections, most closely associated with hematologic stem cell transplant patients
  • Clinical presentations include bacteremia, prosthetic valve endocarditis, meningitis, and peritonitis
  • Essentially universally susceptible to vancomycin and linezolid
  • High rates of resistance to beta lactams; may be fluoroquinolone or tetracycline susceptible[1]
From [1]
Antibiotic Isolates % Susceptible
Penicillin 76 0
Ampicillin 76 ND
Oxacillin 76 ND
Erythromycin 76 11.8
Clindamycin 76 2.6
Ciprofloxacin 75 35.5
Levofloxacin 75 ND
Moxifloxacin 76 35.5
Tetracycline 76 92.1
Vancomycin 76 100
Trimethoprim-sulfamethoxazole 76 18.4
Tigecycline 76 ND
Rifampin 76 97.4
Quinupristin-dalfopristin 76 89.5
Linezolid 76 100
Gentamicin 76 81.6
Daptomycin 75 89.5
Chloramphenicol 75 ND
Nitrofurantoin 76 ND
  1. ↑ 1.0 1.1 Neemuchwala A, Soares D, Ravirajan V, Marchand-Austin A, Kus JV, Patel SN. In Vitro Antibiotic Susceptibility Pattern of Non-diphtheriae Corynebacterium Isolates in Ontario, Canada, from 2011 to 2016. Antimicrob Agents Chemother. 2018 Mar 27;62(4):e01776-17. doi: 10.1128/AAC.01776-17. PMID: 29339389; PMCID: PMC5914010.
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