Carbapenem-resistant organisms: Difference between revisions
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Revision as of 08:15, 21 September 2020
Background
- Mechanisms include decreased expression of porins, increased expression of efflux pumps, and carbapenemases
Management
Antibiotic | KPC | NDM | OXA-48 | CRPsA | CRAcB | Stenotrophomonas |
---|---|---|---|---|---|---|
aztreonam-avibactam | + | + | + | ± | – | + |
cefiderocol | + | + | + | + | + | + |
ceftazidime-avibactam | + | – | + | ± | – | – |
ceftolozane-tazobactam | – | – | – | ± | – | ± |
eravacycline | + | + | + | – | + | + |
fosfomycin | ± | ± | ± | ± | – | – |
imipenem-relebactam | + | – | ± | + | – | – |
meropenem-vaborbactam | + | – | – | – | – | – |
plazomicin | + | ± | + | ± | – | – |
colistin | ± | ± | ± | ± | ± | ± |
tigecycline | + | + | + | – | + | + |