Aplastic anemia: Difference between revisions

Latest revision as of 15:29, 13 September 2020

Background

Pancytopenia with hypocellular bone marrow
May be either acquired or congenital

Differential Diagnosis

Acquired
- Secondary
  - Radiation
  - Drugs and toxins
    - Regular effects
    - Idiosyncratic reactions
  - Viral infections
    - Epstein-Barr virus, as a rare complication of infectious mononucleosis
    - Non-A, non-B, non-C viral hepatitis
    - Parvovirus B19
    - HIV
  - Immune disorders
    - Eosinophilic fasciitis
    - Hypoimmunoglobulinemia
    - Large granular lymphocytosis
    - Thymoma or thymic carcinoma
    - Graft-versus-host disease
    - Paroxysmal nocturnal hemoglobinuria
    - Pregnancy
- Idiopathic
Congenital or inhereted

@@ Line 1: / Line 1: @@
-== Background ==
+==Background==
-* [[Pancytopenia]] with hypocellular bone marrow
+*[[Pancytopenia]] with hypocellular bone marrow
-* May be either acquired or congenital
+*May be either acquired or congenital
-== Differential Diagnosis ==
+==Differential Diagnosis==
-* Acquired
+*Acquired
-** Secondary
+**Secondary
-*** Radiation
+***Radiation
-*** Drugs and toxins
+***Drugs and toxins
-**** Regular effects
+****Regular effects
-**** Idiosyncratic reactions
+****Idiosyncratic reactions
-*** Viral infections
+***Viral infections
-**** [[Epstein-Barr virus]]
+****[[Epstein-Barr virus]], as a rare complication of [[infectious mononucleosis]]
-**** Non-A, non-B, non-C [[viral hepatitis]]
+****Non-A, non-B, non-C [[viral hepatitis]]
-**** [[Parvovirus B19]]
+****[[Parvovirus B19]]
-**** [[HIV]]
+****[[HIV]]
-*** Immune disorders
+***Immune disorders
-**** [[Eosinophilic fasciitis]]
+****[[Eosinophilic fasciitis]]
-**** Hypoimmunoglobulinemia
+****Hypoimmunoglobulinemia
-**** [[Large granular lymphocytosis]]
+****[[Large granular lymphocytosis]]
-**** [[Thymoma]] or [[thymic carcinoma]]
+****[[Thymoma]] or [[thymic carcinoma]]
-**** [[Graft-versus-host disease]]
+****[[Graft-versus-host disease]]
-**** [[Paroxysmal nocturnal hemoglobinuria]]
+****[[Paroxysmal nocturnal hemoglobinuria]]
-**** [[Pregnancy]]
+****[[Pregnancy]]
-** Idiopathic
+**Idiopathic
-* Congenital or inhereted
+*Congenital or inhereted
-** [[Fanconi anemia]]
+**[[Fanconi anemia]]
-** [[Dyskeratosis congenita]] or [[telomere disease]]
+**[[Dyskeratosis congenita]] or [[telomere disease]]
-** [[Schwachman-Diamond syndrome]]
+**[[Schwachman-Diamond syndrome]]
-** [[Familial aplastic anemia]]
+**[[Familial aplastic anemia]]
-** [[Down syndrome]], [[Dubowitz syndrome]], [[Seckel syndrome]]
+**[[Down syndrome]], [[Dubowitz syndrome]], [[Seckel syndrome]]
 [[Category:Hematology]]