Parasitic brain infections
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Differential Diagnosis
Parasite | Disease | Lesion | Location |
---|---|---|---|
Protozoa | |||
Balamuthia mandrillaris and Acanthamoeba species | Granulomatous amoebic encephalitis | single or multiple ring-enhancing lesions with surrounding edema and mass effect | gray and white matter |
Leishmania species | Leishmaniasis | ||
Microsporidia species | Microsporidiasis | ||
Naegleria fowleri | Primary amebic meningoencephalitis | global edema, stroke, and elevated intracranial pressure | base of brain most common |
Plasmodium species | Malaria | ||
Toxoplasma gondii | Toxoplasmosis | ||
Trypanosoma brucei | African trypanosomiasis | diffuse hyperintensity on T1 | bilateral basal ganglia |
Trypanosoma cruzi | Chagas disease | contrast-enhancing hypointense T1 lesions with edema on T2 | parietal and frontal lobes only |
Metazoa: Trematodes | |||
Paragonimus species | Paragonimiasis | inflammatory changes surrounding clusters of contrast-enhancing lesions | frontal and temporal gray and white matter most common |
Schistosoma species | Schistosomiasis | central linear enhancement, clustered with arborized appearance | can include spinal cord, especially with Schistosoma haematobium |
Metazoa: Cestodes | |||
Echinococcus granulosus | Intracranial hydatidosis | multiple thin-walled, large, round cysts, or one large cyst with smaller surrounding cysts | parietal most common |
Echinococcus multilocularis | Alveolar hydatid disease | contrast-enhancing round, solid lesions with surrounding edema on T2 | any |
Taenia solium | Neurocysticercosis | single or multiple ring-enhancing lesions, with calcifications if older | |
Taenia species | Coenurosis | ||
Spirometra species | Sparganosis | T2 edema, sometimes with T1 mass or linear or curvilinear contrast-enhancing lesions | frontal and parietal lobes most common |
Metazoa: Nematodes | |||
Gnathostoma species | Gnathostomiasis | ||
Angiostrongylus cantonensis | Angiostrongyliasis | ||
Toxocara species | Toxocariasis | ||
Strongyloides stercoralis | Strongyloidiasis | ||
multiple | Filariasis | ||
Baylisascaris procyonis | Baylisascariasis | ||
Dracuncula medinensis | Dracunculiasis | ||
Dicrocoelium dendriticum | Dicrocoeliasis | ||
Lagochilascaris species | Lagochilascariasis |