Thrombocytopenia

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Differential Diagnosis

Decreased production
- Viral infection
- Malignancy
Destruction/Consumption
- Immune-mediated thrombocytopenic purpura (ITP)
  - Hepatitis C, HIV, and Helicobacter pylori
- Thrombotic microangiopathy
  - TTP/HUS, other TMAs
Sequestration
- Splenomegaly

Investigations

Rule out secondary causes with hepatitis C virus, HIV, and Helicobacter pylori serology

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Hematology