Corynebacterium jeikeium: Difference between revisions

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Corynebacterium jeikeium
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* Species of [[Corynebacterium|''Corynebacterium'']] that causes opportunistic infections, most closely associated with hematologic stem cell transplant patients
* Species of [[Genus::Corynebacterium]] that causes opportunistic infections, most closely associated with hematologic stem cell transplant patients
* Clinical presentations include bacteremia, prosthetic valve endocarditis, meningitis, and peritonitis
* Clinical presentations include bacteremia, prosthetic valve endocarditis, meningitis, and peritonitis
* Essentially universally susceptible to [[vancomycin]] and [[linezolid]]
* Essentially universally susceptible to [[vancomycin]] and [[linezolid]]

Revision as of 15:09, 27 September 2023

  • Species of Corynebacterium that causes opportunistic infections, most closely associated with hematologic stem cell transplant patients
  • Clinical presentations include bacteremia, prosthetic valve endocarditis, meningitis, and peritonitis
  • Essentially universally susceptible to vancomycin and linezolid
  • High rates of resistance to beta lactams; may be fluoroquinolone or tetracycline susceptible[1]
From [1]
Antibiotic Isolates % Susceptible
Penicillin 76 0
Ampicillin 76 ND
Oxacillin 76 ND
Erythromycin 76 11.8
Clindamycin 76 2.6
Ciprofloxacin 75 35.5
Levofloxacin 75 ND
Moxifloxacin 76 35.5
Tetracycline 76 92.1
Vancomycin 76 100
Trimethoprim-sulfamethoxazole 76 18.4
Tigecycline 76 ND
Rifampin 76 97.4
Quinupristin-dalfopristin 76 89.5
Linezolid 76 100
Gentamicin 76 81.6
Daptomycin 75 89.5
Chloramphenicol 75 ND
Nitrofurantoin 76 ND
  1. 1.0 1.1 Neemuchwala A, Soares D, Ravirajan V, Marchand-Austin A, Kus JV, Patel SN. In Vitro Antibiotic Susceptibility Pattern of Non-diphtheriae Corynebacterium Isolates in Ontario, Canada, from 2011 to 2016. Antimicrob Agents Chemother. 2018 Mar 27;62(4):e01776-17. doi: 10.1128/AAC.01776-17. PMID: 29339389; PMCID: PMC5914010.