Immunodeficiency: Difference between revisions
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(Created page with "* Usually organized into: ** Primary immunodeficiency ** Acquired (secondary) immunodeficiency *** Includes immunosuppressive therapy Category:Immunology Category:Immunocompromised hosts") |
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== Background == |
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* Usually organized into: |
* Usually organized into: |
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** [[Primary immunodeficiency]] |
** [[Primary immunodeficiency]] |
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** [[Acquired immunodeficiency|Acquired (secondary) immunodeficiency]] |
** [[Acquired immunodeficiency|Acquired (secondary) immunodeficiency]] |
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*** Includes [[immunosuppressive therapy]] |
*** Includes [[immunosuppressive therapy]] |
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==Clinical Manifestations== |
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{| class="wikitable" |
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!Immune Defect |
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!Typical Infections |
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!Typical Organisms |
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|cell-mediated (T cells) |
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|persistent viral infections, opportunistic infections, disseminated infections |
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|[[Pneumocystis jirovecii]], [[Cryptococcus]], [[Herpesviridae]] |
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|humoural (B cells) |
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|respiratory infections with [[Encapsulated bacteria|encapsulated organisms]], [[chronic diarrhea]], [[aseptic meningitis]] |
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|[[Haemophilus influenzae]], [[Streptococcus pneumoniae]], [[Giardia lamblia]], [[Campylobacter]], [[Enterovirus|enteroviruses]] |
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|phagocytic |
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|recurrent [[Abscess|abscesses]], [[gingivitis]], [[Aphthous ulcer|aphthous ulcers]] |
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|[[Staphylococcus aureus]], [[Burkholderia cepacia]], [[Serratia marcescens]], [[Aspergillus]], [[Nocardia]] |
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|monocytic |
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|disseminated infections and multifocal [[osteomyelitis]] |
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|[[non-tuberculous mycobacteria]], [[Salmonella]], [[Histoplasma capsulatum]], [[Coccidioides immitis]] |
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|[[Toll-like receptors|TLR]] |
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|recurrent [[meningitis]], [[bacteremia]], absence of fever |
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|[[Streptococcus pneumoniae]], [[Neisseria meningitidis]], [[Staphylococcus aureus]], [[HSV]] |
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|complement |
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|recurrent [[bacteremia]] and [[meningitis]] |
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|[[Neisseria]] |
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|T cells and phagocytes |
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|[[eczema]], [[kyphoscoliosis]], pathologic fratures, pulmonary and cutaneous infections, [[mucocutaneous candidiasis]] |
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|[[Staphylococcus aureus]], [[Haemophilus influenzae]], [[Streptococcus pneumoniae]], [[Candida albicans]] |
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[[Category:Immunology]] |
[[Category:Immunology]] |
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[[Category:Immunocompromised hosts]] |
[[Category:Immunocompromised hosts]] |
Latest revision as of 00:07, 16 February 2023
Background
- Usually organized into: