Staphylococcal toxic shock syndrome: Difference between revisions
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* A [[toxic shock syndrome]] caused by infection with [[Staphylococcus aureus]] |
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#REDIRECT [[Toxic shock syndromes#Staphylococcal_Toxic_Shock_Syndrome]] |
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== Case Definition == |
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Source: [https://wwwn.cdc.gov/nndss/conditions/toxic-shock-syndrome-other-than-streptococcal/case-definition/2011/ CDC case definition 2011] |
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=== Clinical Criteria === |
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An illness with the following clinical manifestations: |
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* '''Fever:''' temperature greater than or equal to 102.0°F (greater than or equal to 38.9°C) |
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* '''Rash:''' diffuse macular erythroderma |
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* '''Desquamation:''' 1-2 weeks after onset of rash |
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* '''Hypotension:''' systolic blood pressure less than or equal to 90 mm Hg for adults or less than fifth percentile by age for children aged less than 16 years |
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* '''Multisystem involvement''' (three or more of the following organ systems): |
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** '''Gastrointestinal:''' vomiting or diarrhea at onset of illness |
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** '''Muscular:''' severe myalgia or creatine phosphokinase level at least twice the upper limit of normal |
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** '''Mucous membrane:''' vaginal, oropharyngeal, or conjunctival hyperemia |
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** '''Renal:''' blood urea nitrogen or creatinine at least twice the upper limit of normal for laboratory or urinary sediment with pyuria (greater than or equal to 5 leukocytes per high-power field) in the absence of urinary tract infection |
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** '''Hepatic:''' total bilirubin, alanine aminotransferase enzyme, or asparate aminotransferase enzyme levels at least twice the upper limit of normal for laboratory |
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** '''Hematologic:''' platelets less than 100,000/mm3 |
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** '''Central nervous system:''' disorientation or alterations in consciousness without focal neurologic signs when fever and hypotension are absent |
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=== Laboratory Criteria for Diagnosis === |
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Negative results on the following tests, if obtained: |
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* Blood or cerebrospinal fluid cultures (blood culture may be positive for Staphylococcus aureus) |
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* Negative serologies for Rocky Mountain spotted fever, leptospirosis, or measles |
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=== Case Classification === |
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* '''Probable:''' A case which meets the laboratory criteria and in which four of the five clinical criteria described above are present |
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* '''Confirmed:''' A case which meets the laboratory criteria and in which all five of the clinical criteria described above are present, including desquamation, unless the patient dies before desquamation occurs |
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[[Category:Infectious syndromes]] |
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Latest revision as of 15:25, 16 December 2019
- A toxic shock syndrome caused by infection with Staphylococcus aureus
Case Definition
Source: CDC case definition 2011
Clinical Criteria
An illness with the following clinical manifestations:
- Fever: temperature greater than or equal to 102.0°F (greater than or equal to 38.9°C)
- Rash: diffuse macular erythroderma
- Desquamation: 1-2 weeks after onset of rash
- Hypotension: systolic blood pressure less than or equal to 90 mm Hg for adults or less than fifth percentile by age for children aged less than 16 years
- Multisystem involvement (three or more of the following organ systems):
- Gastrointestinal: vomiting or diarrhea at onset of illness
- Muscular: severe myalgia or creatine phosphokinase level at least twice the upper limit of normal
- Mucous membrane: vaginal, oropharyngeal, or conjunctival hyperemia
- Renal: blood urea nitrogen or creatinine at least twice the upper limit of normal for laboratory or urinary sediment with pyuria (greater than or equal to 5 leukocytes per high-power field) in the absence of urinary tract infection
- Hepatic: total bilirubin, alanine aminotransferase enzyme, or asparate aminotransferase enzyme levels at least twice the upper limit of normal for laboratory
- Hematologic: platelets less than 100,000/mm3
- Central nervous system: disorientation or alterations in consciousness without focal neurologic signs when fever and hypotension are absent
Laboratory Criteria for Diagnosis
Negative results on the following tests, if obtained:
- Blood or cerebrospinal fluid cultures (blood culture may be positive for Staphylococcus aureus)
- Negative serologies for Rocky Mountain spotted fever, leptospirosis, or measles
Case Classification
- Probable: A case which meets the laboratory criteria and in which four of the five clinical criteria described above are present
- Confirmed: A case which meets the laboratory criteria and in which all five of the clinical criteria described above are present, including desquamation, unless the patient dies before desquamation occurs
