Erythema multiforme: Difference between revisions
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(Created page with "== Background == * Now considered a separate entity from Stevens-Johnson syndrome * More common in young adults, but can develop at any age * Classified as either: ** Minor: localized eruption with mild or no mucosal involvement ** Major: skin and mucosal erosions of raised atypical target lesions === Etiologies === * Drugs ** Antimicrobials *** Penicillins *** Tetracyclines *** Sulfonamides *** Azithromycin *** Antiretrovirals, particularly ...") |
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* Drugs |
* Drugs |
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** Antimicrobials |
** Antimicrobials |
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*** [[Penicillins]] |
*** '''[[Penicillins]]''' |
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| ⚫ | |||
*** [[Tetracyclines]] |
*** [[Tetracyclines]] |
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| ⚫ | |||
*** [[Azithromycin]] |
*** [[Azithromycin]] |
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*** [[Antiretrovirals]], particularly [[nevirapine]] |
*** [[Antiretrovirals]], particularly [[nevirapine]] |
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*** [[Lamotrigine]] |
*** [[Lamotrigine]] |
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** Others |
** Others |
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| ⚫ | |||
*** [[Ethosuximide]] |
*** [[Ethosuximide]] |
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*** [[Cocaine]] |
*** [[Cocaine]] |
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| ⚫ | |||
*** [[Salicylates]] |
*** [[Salicylates]] |
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*** [[Barbiturates]] |
*** [[Barbiturates]] |
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*** [[Allopurinol]] |
*** [[Allopurinol]] |
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* Infections |
* Infections |
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** [[Herpes simplex virus]], types 1 and 2 |
** '''[[Herpes simplex virus]],''' types 1 and 2 (most common) |
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** [[Mycoplasma pneumoniae]] |
** [[Mycoplasma pneumoniae]] |
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** Other viruses: [[parapoxvirus]], [[varicella zoster virus]], [[adenovirus]], [[EBV]], [[CMV]], [[viral hepatitis]], [[coxsackievirus]], [[parvovirus B19]], [[HIV]] |
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** [[Chlamydia psittaci]] |
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** [[Salmonella]] |
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** [[Histoplasmosis]] |
** [[Histoplasmosis]] |
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** [[Tuberculosis]] |
** [[Tuberculosis]] |
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** [[Dermatophytes]] |
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== Clinical Manifestations == |
== Clinical Manifestations == |
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* Asymptomatic, erythematous discrete macules and papules |
* Asymptomatic, erythematous discrete macules and papules |
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* Lesions may have target, iris, or bullseye appearance |
* Lesions may have target-like, iris, or bullseye appearance |
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* Most common on hands, wrists, and ankles |
* Most common on hands, wrists, and ankles |
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* Mucosal involvement of oral cavity is common |
* Mucosal involvement of oral cavity is common |
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** Tongue, palate, buccal mucosa, and gingiva are all commonly involved |
** Tongue, palate, buccal mucosa, and gingiva are all commonly involved |
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[[Category:Dermatology]] |
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Latest revision as of 17:06, 2 November 2022
Background
- Now considered a separate entity from Stevens-Johnson syndrome
- More common in young adults, but can develop at any age
- Classified as either:
- Minor: localized eruption with mild or no mucosal involvement
- Major: skin and mucosal erosions of raised atypical target lesions
Etiologies
- Drugs
- Antimicrobials
- Antiepileptics
- Others
- Infections
- Herpes simplex virus, types 1 and 2 (most common)
- Mycoplasma pneumoniae
- Other viruses: parapoxvirus, varicella zoster virus, adenovirus, EBV, CMV, viral hepatitis, coxsackievirus, parvovirus B19, HIV
- Chlamydia psittaci
- Salmonella
- Histoplasmosis
- Tuberculosis
- Dermatophytes
Clinical Manifestations
- Asymptomatic, erythematous discrete macules and papules
- Lesions may have target-like, iris, or bullseye appearance
- Most common on hands, wrists, and ankles
- Mucosal involvement of oral cavity is common
- Tongue, palate, buccal mucosa, and gingiva are all commonly involved
