Roseomonas: Difference between revisions

Latest revision as of 01:33, 6 July 2022

Background

Microbiology

Genus of slow-growing Gram-negative bacilli or coccobacilli within the family Acetobacteraceae
Previously referred to as CDC pink coccoid groups I through IV
Related to Methylobacterium
Catalase and oxidase positive
Non-fermentative
Aerobic
Pigmented, either pink or purple-pink
Isolated from environmental samples including soil, water, and plants
Species of possible clinical importance include:
- Roseomonas gilardii subspecies gilardii (usually clinically important) and rosea
- Roseomonas mucosa
- Roseomonas fauriae
- Roseomonas genomospecies 4, 5, and 6

Clinical Manifestations

More common in patients with significant comorbidities or immunocompromise
- Malignancy on chemotherapy (solid-organ and hematologic), particularly with neutropenia
- Also advanced HIV, CKD, and diabetes mellitus
Bacteremia (75%), including central line infection
Musculoskeletal infections (8%), including osteomyelitis and septic arthritis
Skin and soft tissue infection (6%)
Peritoneal dialysis-associated peritonitis (6%)
Extremely rare cases of endophthalmitis, endocarditis, pneumonia, ventriculitis, and pre-aortic abscess
Often seen in polymicrobial cultures, particularly coagulase-negative staphylococci, Micrococcus, Pseudomonas, coryneform bacteria, and many others

Management

Generally susceptible to aminoglycosides, tetracycline, and imipenem
May be susceptible to fluoro quinolones
Generally resistant to penicillins (including combinations with β-lactamase inhibitors), cephalosporins, and co-trimoxazole
Remove the central line if CLABSI is suspected

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+== Background ==
-* Genus of [[Stain::Gram-negative]] [[Shape::bacillus]]
-* Pigmented, either pink or purple
+=== Microbiology ===
+* Genus of slow-growing [[Stain::Gram-negative]] [[Shape::bacillus|bacilli]] or [[Shape::coccobacillus|coccobacilli]] within the family [[Family::Acetobacteraceae]]
+* Previously referred to as CDC pink coccoid groups I through IV
+* Related to [[Methylobacterium]]
+* Catalase and oxidase positive
+* Non-fermentative
+* Aerobic
+* Pigmented, either pink or purple-pink
+* Isolated from environmental samples including soil, water, and plants
+* Species of possible clinical importance include:
+** [[Roseomonas gilardii]] subspecies gilardii (usually clinically important) and rosea
+** [[Roseomonas mucosa]]
+** [[Roseomonas fauriae]]
+** ''Roseomonas'' genomospecies 4, 5, and 6
+== Clinical Manifestations ==
+* More common in patients with significant comorbidities or immunocompromise
+** Malignancy on chemotherapy (solid-organ and hematologic), particularly with neutropenia
+** Also advanced HIV, CKD, and diabetes mellitus
+* [[Gram-negative bacteremia|Bacteremia]] (75%), including [[central line infection]]
+* Musculoskeletal infections (8%), including [[osteomyelitis]] and [[septic arthritis]]
+* [[Skin and soft tissue infection]] (6%)
+* [[Peritoneal dialysis-associated peritonitis]] (6%)
+* Extremely rare cases of endophthalmitis, endocarditis, pneumonia, ventriculitis, and pre-aortic abscess
+* Often seen in polymicrobial cultures, particularly [[coagulase-negative staphylococci]], [[Micrococcus]], [[Pseudomonas]], coryneform bacteria, and many others
+== Management ==
+* Generally susceptible to [[aminoglycosides]], [[tetracycline]], and [[imipenem]]
+* May be susceptible to [[fluoroquinolones|fluoro]]{{DISPLAYTITLE:''Roseomonas''}}[[fluoroquinolones|quinolones]]
+* Generally resistant to [[penicillins]] (including combinations with β-lactamase inhibitors), [[cephalosporins]], and [[co-trimoxazole]]
+* Remove the central line if [[CLABSI]] is suspected
+== Further Reading ==
+* ''Roseomonas'' species infections in humans: a systematic review. ''J Chemother''. 2020;32(5):226-236. doi: [https://doi.org/10.1080/1120009x.2020.1785742 10.1080/1120009X.2020.1785742]
-{{DISPLAYTITLE:''Roseomonas''}}
 [[Category:Gram-negative bacilli]]