Chronic bacterial prostatitis: Difference between revisions

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(Created page with "== Background == === Microbiology === * Enterobacterales * Pseudomonas species * Occasionally, Enterococcus species == Clinical Manifestations == * Mild to mod...")
 
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== Background ==
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==Background==
   
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=== Microbiology ===
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===Microbiology===
   
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* [[Enterobacterales]]
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*[[Enterobacterales]]
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* [[Pseudomonas species]]
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*[[Pseudomonas species]]
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* Occasionally, [[Enterococcus species]]
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*Occasionally, [[Enterococcus species]]
   
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== Clinical Manifestations ==
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==Clinical Manifestations==
   
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* Mild to moderate pelvic pain symptoms with recurrent [[Urinary tract infection|urinary tract infections]], typically with the same organism
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*Mild to moderate pelvic pain symptoms with recurrent [[Urinary tract infection|urinary tract infections]], typically with the same organism
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* Prostate is usually normal on physical or endoscopic assessment
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*Prostate is usually normal on physical or endoscopic assessment
   
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== Diagnosis ==
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==Diagnosis==
   
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* The gold standard is the 4-glass test
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*The gold standard is the 4-glass test
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** Sample 1: first void (5-10 mL)
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**Sample 1: first void (5-10 mL)
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** Sample 2: midstream
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**Sample 2: midstream
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** Sample 3: expressed prostatic secretions
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**Sample 3: expressed prostatic secretions
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** Sample 4: first void after prostatic massage (5-10 mL)
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**Sample 4: first void after prostatic massage (5-10 mL)
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** Positive if sample 4 has ≥10 times the colony count of sample 1
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**Positive if sample 4 has ≥10 times the colony count of sample 1
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* Can also do 2-glass pre- and post-massage test
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*Can also do 2-glass pre- and post-massage test
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** Sample 1: midstream urine (10 mL)
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**Sample 1: midstream urine (10 mL)
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** Sample 2: first void after prostate massage (10 mL)
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**Sample 2: first void after prostate massage (10 mL)
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** Positive if sample 2 has ≥10 times the colony count of sample 1
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**Positive if sample 2 has ≥10 times the colony count of sample 1
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* Semen cultures are not recommended
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*Semen cultures are not recommended
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* Prostatic ultrasonography is not recommended
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*Prostatic ultrasonography is not recommended
   
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== Management ==
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==Management==
   
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* First-line treatment is [[fluoroquinolones]] for 4 to 6 weeks
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*First-line treatment is [[fluoroquinolones]] for 4 to 6 weeks
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* Alternatives include [[fosfomycin]]
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*Alternatives include [[fosfomycin]] or [[TMP-SMX]]
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* Acutely ill patients should be treated with a third-generation [[Cephalosporins|cephalosporin]] or [[Carbapenems|carbapenem]]
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*Acutely ill patients should be treated with a third-generation [[Cephalosporins|cephalosporin]] or [[Carbapenems|carbapenem]]
   
 
[[Category:Genitourinary infections]]
 
[[Category:Genitourinary infections]]

Revision as of 14:20, 14 September 2020

Background

Microbiology

Clinical Manifestations

  • Mild to moderate pelvic pain symptoms with recurrent urinary tract infections, typically with the same organism
  • Prostate is usually normal on physical or endoscopic assessment

Diagnosis

  • The gold standard is the 4-glass test
    • Sample 1: first void (5-10 mL)
    • Sample 2: midstream
    • Sample 3: expressed prostatic secretions
    • Sample 4: first void after prostatic massage (5-10 mL)
    • Positive if sample 4 has ≥10 times the colony count of sample 1
  • Can also do 2-glass pre- and post-massage test
    • Sample 1: midstream urine (10 mL)
    • Sample 2: first void after prostate massage (10 mL)
    • Positive if sample 2 has ≥10 times the colony count of sample 1
  • Semen cultures are not recommended
  • Prostatic ultrasonography is not recommended

Management