Corynebacterium jeikeium: Difference between revisions
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Corynebacterium jeikeium
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− | * Species of [[Corynebacterium |
+ | * Species of [[Genus::Corynebacterium]] that causes opportunistic infections, most closely associated with hematologic stem cell transplant patients |
* Clinical presentations include bacteremia, prosthetic valve endocarditis, meningitis, and peritonitis |
* Clinical presentations include bacteremia, prosthetic valve endocarditis, meningitis, and peritonitis |
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* Essentially universally susceptible to [[vancomycin]] and [[linezolid]] |
* Essentially universally susceptible to [[vancomycin]] and [[linezolid]] |
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+ | * High rates of resistance to beta lactams; may be fluoroquinolone or tetracycline susceptible[[CiteRef::nemuchwala2018in]] |
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− | * High rates of resistance to beta lactams; may be fluoroquinolone or tetracycline susceptible<ref name=":0">Neemuchwala A, Soares D, Ravirajan V, Marchand-Austin A, Kus JV, Patel SN. ''In Vitro'' Antibiotic Susceptibility Pattern of Non-diphtheriae Corynebacterium Isolates in Ontario, Canada, from 2011 to 2016. Antimicrob Agents Chemother. 2018 Mar 27;62(4):e01776-17. doi: [https://doi.org/10.1128/aac.01776-17 10.1128/AAC.01776-17]. PMID: [https://pubmed.ncbi.nlm.nih.gov/29339389/ 29339389]; PMCID: [http://www.ncbi.nlm.nih.gov/pmc/articles/pmc5914010/ PMC5914010].</ref> |
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+ | |||
{| class="wikitable sortable" |
{| class="wikitable sortable" |
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− | |+From |
+ | |+From [[CiteRef::nemuchwala2018in]] |
!Antibiotic |
!Antibiotic |
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!Isolates |
!Isolates |
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|[[Nitrofurantoin]] |
|[[Nitrofurantoin]] |
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|76 |
|76 |
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− | |ND |
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− | |} |
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− | {| class="wikitable" |
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− | | |
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− | | |
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− | | |
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− | | |
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− | | |
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− | | |
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− | |- |
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− | |Penicillin |
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− | |76 |
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− | |0.5 to >8 |
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− | |>8 |
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− | |>8 |
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− | |0 |
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− | |- |
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− | | Ampicillin |
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− | |76 |
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− | |≤0.12 to >8 |
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− | |>8 |
||
− | |>8 |
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− | |ND |
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− | |- |
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− | | Oxacillin |
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− | |76 |
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− | |0.5 to >4 |
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− | |>4 |
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− | |>4 |
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− | |ND |
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− | |- |
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− | | Erythromycin |
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− | |76 |
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− | |≤0.25 to >4 |
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− | |>4 |
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− | |>4 |
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− | |11.8 |
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− | |- |
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− | | Clindamycin |
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− | |76 |
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− | |≤0.5 to >2 |
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− | |>2 |
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− | |>2 |
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− | |2.6 |
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− | |- |
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− | | Ciprofloxacin |
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− | |75 |
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− | |≤1 to >2 |
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− | |>2 |
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− | |>2 |
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− | |35.5 |
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− | |- |
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− | | Levofloxacin |
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− | |75 |
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− | |≤0.25 to >4 |
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− | |>4 |
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− | |>4 |
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− | |ND |
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− | |- |
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− | | Moxifloxacin<sup>''b''</sup> |
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− | |76 |
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− | |≤0.25 to >4 |
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− | |4 |
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− | |>4 |
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− | |35.5 |
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− | |- |
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− | | Tetracycline |
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− | |76 |
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− | |≤2 to >16 |
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− | |≤2 |
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− | |≤2 |
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− | |92.1 |
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− | |- |
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− | | Vancomycin |
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− | |76 |
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− | |≤0.25 to 2 |
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− | |0.50 |
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− | |1 |
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− | |100 |
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− | |- |
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− | | Trimethoprim-sulfamethoxazole |
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− | |76 |
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− | |≤0.5 to >4 |
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− | |>4 |
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− | |>4 |
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− | |18.4 |
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− | |- |
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− | | Tigecycline |
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− | |76 |
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− | |≤0.03 to >0.5 |
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− | |0.12 |
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− | |0.25 |
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− | |ND |
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− | |- |
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− | | Rifampin |
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− | |76 |
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− | |≤0.5 to >4 |
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− | |≤0.5 |
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− | |≤0.5 |
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− | |97.4 |
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− | |- |
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− | | Quinupristin-dalfopristin |
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− | |76 |
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− | |≤0.5 to 4 |
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− | |≤0.5 |
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− | |2 |
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− | |89.5 |
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− | |- |
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− | | Linezolid |
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− | |76 |
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− | |≤1 |
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− | |≤1 |
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− | |≤1 |
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− | |100 |
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− | |- |
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− | | Gentamicin |
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− | |76 |
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− | |≤2 to >16 |
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− | |≤2 |
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− | |>16 |
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− | |81.6 |
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− | |- |
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− | | Daptomycin |
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− | |75 |
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− | |≤0.5 to >4 |
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− | |≤0.5 |
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− | |1 |
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− | |89.5 |
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− | |- |
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− | | Chloramphenicol |
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− | |75 |
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− | |≤2 to >16 |
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− | |4 |
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− | |16 |
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− | |ND |
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− | |- |
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− | | Nitrofurantoin |
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− | |76 |
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− | |≤32 to >64 |
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− | |>64 |
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− | |>64 |
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|ND |
|ND |
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|} |
|} |
Latest revision as of 13:44, 19 September 2024
- Species of Corynebacterium that causes opportunistic infections, most closely associated with hematologic stem cell transplant patients
- Clinical presentations include bacteremia, prosthetic valve endocarditis, meningitis, and peritonitis
- Essentially universally susceptible to vancomycin and linezolid
- High rates of resistance to beta lactams; may be fluoroquinolone or tetracycline susceptible1
Antibiotic | Isolates | % Susceptible |
---|---|---|
Penicillin | 76 | 0 |
Ampicillin | 76 | ND |
Oxacillin | 76 | ND |
Erythromycin | 76 | 11.8 |
Clindamycin | 76 | 2.6 |
Ciprofloxacin | 75 | 35.5 |
Levofloxacin | 75 | ND |
Moxifloxacin | 76 | 35.5 |
Tetracycline | 76 | 92.1 |
Vancomycin | 76 | 100 |
Trimethoprim-sulfamethoxazole | 76 | 18.4 |
Tigecycline | 76 | ND |
Rifampin | 76 | 97.4 |
Quinupristin-dalfopristin | 76 | 89.5 |
Linezolid | 76 | 100 |
Gentamicin | 76 | 81.6 |
Daptomycin | 75 | 89.5 |
Chloramphenicol | 75 | ND |
Nitrofurantoin | 76 | ND |