MexXY-OprM efflux pump

• Efflux pump in Pseudomonas aeruginosa
• Confers resistance to fluoroquinolones, macrolides, tetracyclines, aminoglycosides, chloramphenicol, lincomycin, and most β-lactams
• Does not confer resistance to novobiocin, polymyxin B, and some β-lactams (carbenicillin, sulbenicillin, cefsulodin, ceftazidime, oxacephem, imipenem, and aztreonam)