Carbapenem-resistant Enterobacterales
From IDWiki
Management
- See also Carbapenem-resistant organisms
- First-line includes meropenem-vaborbactam or ceftazidime-avibactam, directed by susceptibility resultsCiteRef:paul2022eu
- For metallo-β-lactamases or extensively resistant bacteria, consider cefiderocol or aztreonam 2 g IV q8h plus ceftazidime-avibactam 2.5 g IV q8h (both run concurrently over 3 hours)
- For non-severe infections, consider aminoglycosides, including plazomicin; tigecycline would be second-line, though it can be considered in pneumonia
