Uveitis: Difference between revisions

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==Background==
 
==Background==
  +
βˆ’
* Inflammation of the uvea, which comprises the iris, ciliary body, and choroid, or of the retina
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*Inflammation of the uvea, which comprises the iris, ciliary body, and choroid, or of the retina
βˆ’
** Anterior: iritis, iridocyclitis
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**Anterior: iritis, iridocyclitis
βˆ’
** Intermediate: pars planitis
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**Intermediate: pars planitis
βˆ’
** Posterior: choroiditis, retinitis, chorioretinitis
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**Posterior: choroiditis, retinitis, chorioretinitis
βˆ’
** Panuveitis
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**Panuveitis
   
 
==Differential Diagnosis==
 
==Differential Diagnosis==
 
===Infectious causes===
 
===Infectious causes===
  +
* Anterior uveitis (10% infectious)
 
βˆ’
** [[Herpes simplex virus]] (by far the most common infectious cause)
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*Anterior uveitis (10% infectious)
  +
**[[Herpes simplex virus]] (by far the most common infectious cause)
** [[Varicella-zoster virus]]
 
βˆ’
** [[Syphilis]]
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**[[Varicella-zoster virus]]
βˆ’
** [[Tuberculosis]]
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**[[Syphilis]]
βˆ’
** [[Lyme disease]]
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**[[Tuberculosis]]
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** [[Leprosy]]
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**[[Lyme disease]]
  +
**[[Leprosy]]
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* Intermediate uveitis (rarely infectious)
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*Intermediate uveitis (rarely infectious)
βˆ’
** [[Lyme disease]]
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**[[Lyme disease]]
βˆ’
* Posterior uveitis (50% infectious)
 
 
*Posterior uveitis (50% infectious)
βˆ’
** [[Toxoplasmosis]]
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**[[Toxoplasmosis]]
βˆ’
** [[Acute retinal necrosis]] from [[HSV]], [[VZV]], and [[CMV]]
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**[[Acute retinal necrosis]] from [[HSV]], [[VZV]], and [[CMV]]
βˆ’
** [[CMV]] retinitis, in immunocompromised patients
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**[[CMV]] retinitis, in immunocompromised patients
βˆ’
** [[Toxocara]]
 
βˆ’
** [[Syphilis]]
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**[[Toxocara]]
βˆ’
** [[Cat-scratch disease]]
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**[[Syphilis]]
  +
**[[Cat-scratch disease]]
βˆ’
** [[Candida]] endophthalmitis
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**[[Candida]] endophthalmitis
βˆ’
** [[West Nile virus]], causing a multifocal chorioretinitis
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**[[West Nile virus]], causing a multifocal chorioretinitis
βˆ’
* Panuveitis
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*Panuveitis
βˆ’
** [[Syphilis]]
 
βˆ’
** [[Tuberculosis]]
+
**[[Syphilis]]
  +
**[[Tuberculosis]]
βˆ’
** [[Candida]] endophthalmitis
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**[[Candida]] endophthalmitis
βˆ’
** [[Leptospirosis]], without retinal or choroidal lesions
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**[[Leptospirosis]], without retinal or choroidal lesions
βˆ’
* Other
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*Other
βˆ’
** [[Brucella]], causing a chronic relapsing uveitis that is typically posterior but can be anterior or panuveitis[[CiteRef::rolando2008oc]]
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**[[Brucella]], causing a chronic relapsing uveitis that is typically posterior but can be anterior or panuveitis[[CiteRef::rolando2008oc]]
βˆ’
** [[Chikungunya]]
 
βˆ’
** [[Ebola virus]]
+
**[[Chikungunya]]
βˆ’
** [[Zika virus]]
+
**[[Ebola virus]]
 
**[[Zika virus]]
  +
  +
== Clinical Manifestations ==
  +
  +
* Anterior: painful red eye and vision loss
  +
* Intermediate: vision loss with floaters, usually painless (and rarely infectious)
  +
* Posterior: painless vision loss
   
 
[[Category:Ophthalmology]]
 
[[Category:Ophthalmology]]
  +
[[Category:Infectious diseases]]
  +
[[Category:Eye infections]]

Latest revision as of 10:38, 12 August 2020

Background

  • Inflammation of the uvea, which comprises the iris, ciliary body, and choroid, or of the retina
    • Anterior: iritis, iridocyclitis
    • Intermediate: pars planitis
    • Posterior: choroiditis, retinitis, chorioretinitis
    • Panuveitis

Differential Diagnosis

Infectious causes

Clinical Manifestations

  • Anterior: painful red eye and vision loss
  • Intermediate: vision loss with floaters, usually painless (and rarely infectious)
  • Posterior: painless vision loss

References

  1. ^  Isaias Rolando, Liset Olarte, Gustavo Vilchez, Marina Lluncor, Larissa Otero, Mark Paris, Carlos Carrillo, Eduardo Gotuzzo. Ocular Manifestations Associated with Brucellosis: A 26‐Year Experience in Peru. Clinical Infectious Diseases. 2008;46(9):1338-1345. doi:10.1086/529442.