Piperacillin-tazobactam: Difference between revisions

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== Background ==
+
==Background==
   
=== Clinical Breakpoints ===
+
===Clinical Breakpoints===
 
{| class="wikitable"
 
{| class="wikitable"
 
! rowspan="2" |Species
 
! rowspan="2" |Species
 
! rowspan="2" |ECV (μg/mL)
 
! rowspan="2" |ECV (μg/mL)
! colspan="4" |Breakpoints (μg/mL)
+
! colspan="3" |Breakpoints (μg/mL)
! colspan="4" |Breakpoints (mm)
+
! colspan="3" |Breakpoints (mm)
 
|-
 
|-
 
!S
 
!S
 
!I
 
!I
!SDD
 
 
!R
 
!R
 
!S
 
!S
 
!I
 
!I
!SDD
 
 
!R
 
!R
 
|-
 
|-
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|≤16/4
 
|≤16/4
 
|32/4-64/4
 
|32/4-64/4
|—
 
 
|≥128/4
 
|≥128/4
 
|≥21
 
|≥21
 
|18-20
 
|18-20
|—
 
 
|≤17
 
|≤17
 
|-
 
|-
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|≤16/4
 
|≤16/4
 
|32/4-64/4
 
|32/4-64/4
|—
 
 
|≥128/4
 
|≥128/4
 
|≥21
 
|≥21
 
|15-20
 
|15-20
|—
 
 
|≤14
 
|≤14
 
|-
 
|-
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|≤16/4
 
|≤16/4
 
|32/4-64/4
 
|32/4-64/4
|—
 
 
|≥128/4
 
|≥128/4
 
|≥21
 
|≥21
 
|18-20
 
|18-20
|—
 
 
|≤17
 
|≤17
 
|-
 
|-
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|≤16/4
 
|≤16/4
 
|32/4-64/4
 
|32/4-64/4
|—
 
 
|≥128/4
 
|≥128/4
|
 
 
|
 
|
 
|
 
|
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|≤16/4
 
|≤16/4
 
|32/4-64/4
 
|32/4-64/4
|—
 
 
|≥128/4
 
|≥128/4
|
 
 
|
 
|
 
|
 
|
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|
 
|
 
|≤1/4
 
|≤1/4
|—
 
 
|—
 
|—
 
|≥2/4
 
|≥2/4
 
|≥21
 
|≥21
|—
 
 
|—
 
|—
 
|—
 
|—
 
|-
 
|-
 
|Gram-positive bacteria
 
|Gram-positive bacteria
| colspan="9" |susceptibility predicted by [[penicillin]]
+
| colspan="7" |susceptibility predicted by [[penicillin]]
 
|}
 
|}
 
[[Category:Β-lactams]]
 
[[Category:Β-lactams]]

Revision as of 11:25, 13 September 2020

Background

Clinical Breakpoints

Species ECV (μg/mL) Breakpoints (μg/mL) Breakpoints (mm)
S I R S I R
Enterobacterales ≤16/4 32/4-64/4 ≥128/4 ≥21 18-20 ≤17
Pseudomonas aeruginosa ≤16/4 32/4-64/4 ≥128/4 ≥21 15-20 ≤14
Acinetobacter species ≤16/4 32/4-64/4 ≥128/4 ≥21 18-20 ≤17
Other non-Enterobacterales ≤16/4 32/4-64/4 ≥128/4
Anaerobes ≤16/4 32/4-64/4 ≥128/4
Haemophilus influenzae and Haemophilus parainfluenzae ≤1/4 ≥2/4 ≥21
Gram-positive bacteria susceptibility predicted by penicillin