| Ethnicity | Age at Onset | Duration | Lymphadenopathy | Abdo Pain | MSK | Chest Pain | Rash | Other | Treatment | |
|---|---|---|---|---|---|---|---|---|---|---|
| FMF | Armenian, Arab, Jewish, Turkish | <20 years | 1-4 days | rare | very common sterile peritonitis | monoarthritis of knee, ankle, wrist | pleuritis, often unilateral | rare erysipelas-like on legs | pericarditis, scrotal attacks, splenomegaly | colchicine |
| HIDS | Dutch, French | childhood | 3-7 days | cervical | very common | arthralgias, rare arthritis | unusual | very common, maculopapular | hepatosplenomegaly, aphthous ulcers | etanercept, IL-1 inhibitors |
| NAPS12 | Guadeloupe, Italy | neonatal | 2-10 days | yes | yes | arthralgias, myalgias | yes | urticaria/erythema | cold sensitivity, headache | — |
| TRAPS | mostly northern European, but all ethnic groups | variable | more than 5 days, up to weeks to months | common | common | arthralgias, myalgias | yes | common erysipelas-like including arms | periorbital edema, headache | IL-1 inhibitors, TNF-α inhibitors, anti-IL6R mAb |
| CAPS | all ethnic groups | childhood/neonatal | variable, depending on subtype | very rare | rarerare | arthralgias, arthritis, bony overgrowth (depending on subtype) | no | urticaria, erythema | cold sensitivity, deafness, aseptic meningitis, papilledema, dysmorphism (depending on subtype) | IL-1 inhibitors |
| PFAPA | all ethnic groups | <5 years | 3 to 6 days | cervical | common | arthralgias | rare | common | aphthous stomatitis, pharyngitis, headache | corticosteroids, cimetidine, tonsillectomy |
