Kawasaki disease: Difference between revisions

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== Diagnostic Criteria ==
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==Diagnostic Criteria==
   
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*"Warm CREAM" mnemonic: fever plus conjunctivitis, rash, extremity involvement, adenopathy, and mucosal involvement
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* "Warm CREAM"
 
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* Fever persisting at least 5 d - Presence of at least 4 principal features:
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*Fever persisting at least 5 d - Presence of at least 4 principal features:
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** Changes in extremities
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**Changes in extremities
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*** Acute: Erythema of palms, soles; edema of hands, feet
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***Acute: Erythema of palms, soles; edema of hands, feet
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*** Subacute: Periungual peeling of fingers, toes in weeks 2 and 3
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***Subacute: Periungual peeling of fingers, toes in weeks 2 and 3
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** Polymorphous exanthem
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**Polymorphous exanthem
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** Bilateral bulbar conjunctival injection without exudate
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**Bilateral bulbar conjunctival injection without exudate
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** Changes in lips and oral cavity: Erythema, lips cracking, strawberry tongue, diffuse injection of oral and pharyngeal mucosae
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**Changes in lips and oral cavity: Erythema, lips cracking, strawberry tongue, diffuse injection of oral and pharyngeal mucosae
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** Cervical lymphadenopathy (>1.5-cm diameter), usually unilateral
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**Cervical lymphadenopathy (>1.5-cm diameter), usually unilateral
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* Exclusion of other diseases with similar findings‡
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*Exclusion of other diseases with similar findings‡
   
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=== Incomplete Kawasaki disease ===
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===Incomplete Kawasaki disease===
   
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* Do not meet the full criteria above
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*Do not meet the full criteria above
   
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== Differential Diagnosis ==
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==Differential Diagnosis==
   
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* Viral infections: measles, adenovirus, enterovirus, Epstein-Barr virus (EBV)
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*Viral infections: [[measles]], [[adenovirus]], [[enterovirus]], [[Epstein-Barr virus]]
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* Scarlet fever
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*[[Scarlet fever]]
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* Staphylococcal scalded skin syndrome
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*[[Staphylococcal scalded skin syndrome]]
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* Toxic shock syndrome
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*[[Toxic shock syndrome]]
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* Bacterial cervical lymphadenitis
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*Bacterial cervical lymphadenitis
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* Drug hypersensitivity reactions
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*Drug hypersensitivity reactions
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* Stevens-Johnson syndrome
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*[[Stevens-Johnson syndrome]]
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* Juvenile rheumatoid arthritis
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*[[Juvenile rheumatoid arthritis]]
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* Rocky Mountain spotted fever
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*[[Rocky Mountain spotted fever]]
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* Leptospirosis
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*[[Leptospirosis]]
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* Mercury hypersensitivity reaction (acrodynia)
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*Mercury hypersensitivity reaction (acrodynia)
   
 
[[Category:Pediatrics]]
 
[[Category:Pediatrics]]

Revision as of 11:37, 30 July 2020

Diagnostic Criteria

  • "Warm CREAM" mnemonic: fever plus conjunctivitis, rash, extremity involvement, adenopathy, and mucosal involvement
  • Fever persisting at least 5 d - Presence of at least 4 principal features:
    • Changes in extremities
      • Acute: Erythema of palms, soles; edema of hands, feet
      • Subacute: Periungual peeling of fingers, toes in weeks 2 and 3
    • Polymorphous exanthem
    • Bilateral bulbar conjunctival injection without exudate
    • Changes in lips and oral cavity: Erythema, lips cracking, strawberry tongue, diffuse injection of oral and pharyngeal mucosae
    • Cervical lymphadenopathy (>1.5-cm diameter), usually unilateral
  • Exclusion of other diseases with similar findings‡

Incomplete Kawasaki disease

  • Do not meet the full criteria above

Differential Diagnosis