Kawasaki disease: Difference between revisions
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+ | ==Diagnostic Criteria== |
+ | *"Warm CREAM" mnemonic: fever plus conjunctivitis, rash, extremity involvement, adenopathy, and mucosal involvement |
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− | * "Warm CREAM" |
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− | * |
+ | *Fever persisting at least 5 d - Presence of at least 4 principal features: |
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+ | **Changes in extremities |
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+ | ***Acute: Erythema of palms, soles; edema of hands, feet |
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+ | ***Subacute: Periungual peeling of fingers, toes in weeks 2 and 3 |
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+ | **Polymorphous exanthem |
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+ | **Bilateral bulbar conjunctival injection without exudate |
− | ** |
+ | **Changes in lips and oral cavity: Erythema, lips cracking, strawberry tongue, diffuse injection of oral and pharyngeal mucosae |
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+ | **Cervical lymphadenopathy (>1.5-cm diameter), usually unilateral |
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+ | *Exclusion of other diseases with similar findings‡ |
− | === |
+ | ===Incomplete Kawasaki disease=== |
− | * |
+ | *Do not meet the full criteria above |
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+ | ==Differential Diagnosis== |
− | * |
+ | *Viral infections: [[measles]], [[adenovirus]], [[enterovirus]], [[Epstein-Barr virus]] |
− | * |
+ | *[[Scarlet fever]] |
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+ | *[[Staphylococcal scalded skin syndrome]] |
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+ | *[[Toxic shock syndrome]] |
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+ | *Bacterial cervical lymphadenitis |
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+ | *Drug hypersensitivity reactions |
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+ | *[[Stevens-Johnson syndrome]] |
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+ | *[[Juvenile rheumatoid arthritis]] |
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+ | *[[Rocky Mountain spotted fever]] |
− | * |
+ | *[[Leptospirosis]] |
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+ | *Mercury hypersensitivity reaction (acrodynia) |
[[Category:Pediatrics]] |
[[Category:Pediatrics]] |
Revision as of 11:37, 30 July 2020
Diagnostic Criteria
- "Warm CREAM" mnemonic: fever plus conjunctivitis, rash, extremity involvement, adenopathy, and mucosal involvement
- Fever persisting at least 5 d - Presence of at least 4 principal features:
- Changes in extremities
- Acute: Erythema of palms, soles; edema of hands, feet
- Subacute: Periungual peeling of fingers, toes in weeks 2 and 3
- Polymorphous exanthem
- Bilateral bulbar conjunctival injection without exudate
- Changes in lips and oral cavity: Erythema, lips cracking, strawberry tongue, diffuse injection of oral and pharyngeal mucosae
- Cervical lymphadenopathy (>1.5-cm diameter), usually unilateral
- Changes in extremities
- Exclusion of other diseases with similar findings‡
Incomplete Kawasaki disease
- Do not meet the full criteria above
Differential Diagnosis
- Viral infections: measles, adenovirus, enterovirus, Epstein-Barr virus
- Scarlet fever
- Staphylococcal scalded skin syndrome
- Toxic shock syndrome
- Bacterial cervical lymphadenitis
- Drug hypersensitivity reactions
- Stevens-Johnson syndrome
- Juvenile rheumatoid arthritis
- Rocky Mountain spotted fever
- Leptospirosis
- Mercury hypersensitivity reaction (acrodynia)